(HealthDay News) — Patients who shared a financial incentive with their doctor to lower their levels of LDL cholesterol achieved a statistically significant reduction after a year of treatment, according to findings published in the Journal of the American Medical Association

The study involved 340 primary care physicians at 3 northeastern U.S. medical clinics, and 1503 of their patients. All of the study volunteers were provided with an electronic pill bottle to track whether they took their statins on schedule. 

Each physician/patient team was placed into 1 of 4 groups. In the first group, doctors were offered up to $1024 for each patient whose cholesterol met a target goal. The second group offered the same cash reward just to patients who took their medication on time. The third group offered shared incentives. The fourth group served as a control group.

Only patients in the shared physician-patient incentives group achieved reductions in LDL cholesterol levels that were statistically different from those in the control group, the researchers found. However, the difference was just 8.5 mg/dL, which amounts to only a 4% reduction in cardiovascular events such as strokes or heart attacks, Pam Morris, MD, told HealthDay

Dr Morris is an assistant professor and director of preventive cardiology at the Medical University of South Carolina and chair of the Prevention of Cardiovascular Disease Committee for the American College of Cardiology.

“It was a very modest effect,” Dr Morris said. “It raises questions about the cost-effectiveness of this model.” 

Morris also noted that most patients failed to take their medication even when offered cash bonuses. Average adherence rates were 39% in the shared-incentive group, and 34% in the patient-incentive group.


  1. Asch DA, Troxel AB, Stewart WF, et al. Effect of Financial Incentives to Physicians, Patients, or Both on Lipid Levels: A Randomized Clinical Trial. JAMA. 2015;314(18):1926-1935.