(HealthDay News) — Fruit and vegetable intake is associated with hip fracture, with a higher rate of hip fracture for intake below five servings per day, according to a study published in the Journal of Bone and Mineral Research.
Liisa Byberg, PhD, from Uppsala University in Sweden, and colleagues examined the dose-response association between habitual fruit and vegetable intake and hip fracture in a cohort study involving 40,644 men and 34,947 women aged 45 to 83 years, free from cardiovascular disease and cancer.
Participants were followed for a mean of 14.2 years.
The researchers observed 3,644 hip fractures (62% in women) during 1,037,645 person-years.
Results revealed a strong nonlinear dose-response association (P<.001). Compared with those consuming more than five servings per day, men and women with zero consumption had an 88% higher rate of hip fracture (adjusted HR=1.88). With higher intake of fruit and vegetables, the rate was gradually lower (adjusted HR=1.35 for one vs. five servings per day).
The hazard ratio was no lower for more than five servings per day (adjusted HR for eight vs. five servings per day=0.96; 95% CI, 0.90-1.03). The results were similar when men and women were analyzed separately.
“There is a dose-response association between fruit and vegetable intake and hip fracture such that an intake below the recommended five servings/day confers higher rates of hip fracture,” the researchers wrote.