Many observational studies in medical literature support the overall benefits of vitamin D supplementation. However, whether this is actually true is the subject of a renewed debate, particularly in muscle health.
Alendronate (Alen), a bisphosphonate used to treat and prevent osteoporosis, was coupled with nanodiamonds (NDs) as part of an experiment to discover if the combination could be used as a potential osteoporosis therapy and provide greater bone-targeted drug delivery than oral osteoporosis medications.
In a poster presented at ASBMR 2021, researchers compared fracture rates and treatment adherence in women with osteoporosis who received risedronate gastro-resistant vs oral immediate-release bisphosphonates.
Primary or age-related sarcopenia is recognized as an independent disease, and advanced glycation end products (AGEs) have been associated in the pathogenesis of primary sarcopenia and other diseases related to aging. Researchers are looking for novel, less invasive ways to predict its severity and course.