Bone Metabolism

Latest News

Infrequent Dosing of Zoledronate May Prevent Bone Loss in Postmenopausal Women

By

Amit Akirov, MD

In postmenopausal women with osteoporosis, 2 doses of zoledronate 5 mg at an approximately 6-year interval prevented bone loss for almost 11 years.

Tramadol Use Linked to Increased Risk for Hip Fracture

By

Morgan E. Meissner

Tramadol use is associated with increased risk for hip fracture compared with other commonly prescribed pain medications.

Endocrine Society Updates Postmenopausal Osteoporosis Management Guidelines to Include Romosozumab

By

Rachael Beairsto

The Endocrine Society has issued an update to the organization’s 2019 clinical practice guideline on pharmacologic management of osteoporosis to include romosozumab.

Exercise Program Reduces Fear of Falling in Women With Osteoporosis, Vertebral Fractures

By

Endocrinology Advisor Contributing Writer

Women with osteoporosis and a history of vertebral fractures had improved balance and muscle strength and reduced fear of falling after participation in a supervised, multicomponent balance and resistance exercise program.

Red Cell Distribution Width Linked to Fracture Risk in Older Men With Anemia

By

Morgan E. Meissner

Red cell distribution width values are associated with risk for fracture in older men, particularly those with anemia.

Oral Bisphosphonates Do Not Increase Mortality Risk in Patients With Chronic Kidney Disease

By

Amit Akirov, MD

Oral bisphosphonate treatment was not associated with increased all-cause mortality risk in patients with moderate to severe chronic kidney disease.

Assessment of Bone Density in axSpA Benefits From Inclusion of Lateral DXA

By

Endocrinology Advisor Contributing Writer

In patients with axial spondyloarthritis, use of lateral DXA, as opposed to the conventional anteroposterior projection, significantly increased the prevalence of low BMD measurements.

Effects of Calcium Supplements on Bone Health Across the Menopausal Transition

By

Amit Akirov, MD

The use of calcium dietary supplements was found to be associated with slower decline in femoral neck and lumbar spine bone mineral density across the menopausal transition.

Women With Anorexia Nervosa at High Risk for Bone Fractures

By

Laurel Ranger

A study found that patients with anorexia nervosa have a particularly high risk for hip, vertebral, and upper arm fractures.

Delayed Denosumab Injections May Be Associated With Suboptimal Bone Mineral Density Response

By

Endocrinology Advisor Contributing Writer

Researchers examined the association between delays in injections of denosumab and bone mineral density change.

Vitamin D Supplementation Alone Does Not Increase Bone Structure, Strength

By

Morgan E. Meissner

In older adults, no significant changes in bone strength or structure were noted after 2 years of daily vitamin D supplementation.