(HealthDay News) — Statin use is not associated with higher risk for gonado-sexual dysfunction in women, according to a study published in the Journal of Sexual Medicine.

Sayed K. Ali, MD, from the VA South Texas Health Care System in San Antonio, and colleagues compared the risk for gonado-sexual dysfunction in statin users and nonusers using data from female adult patients (mean age, 58 years) enrolled in the Tricare Prime/Plus San Antonio catchment area. 

Baseline characteristics were evaluated Oct. 1, 2003, to Sept. 30, 2005, while outcomes (menstrual disorders, menopausal disorders, infertility and ovarian/sexual dysfunction) were evaluated over a follow-up period from Oct. 1, 2005, to March 1, 2012.

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The researchers found that, based on analysis of the propensity score-matched 2,890 statin users and 2,890 nonusers, statin use was not significantly associated with menstrual disorders (OR=0.97; 95% CI, 0.81-1.16), menopausal disorders (OR=0.92; 95% CI, 0.83-1.02), infertility (OR=0.79; 95% CI, 0.36-1.73) or ovarian/sexual dysfunction (OR=1.18; 95% CI, 0.83-1.70).

“Statin use was not associated with higher risk of gonado-sexual dysfunction in women,” the researchers wrote.


  1. Ali SK et al. J Sex Med. 2014;doi:10.1111/jsm.12736.