(HealthDay News) — For couples with early pregnancy loss, there is no indication of improved live birth rates with delayed next attempt at pregnancy, according to a study published in Obstetrics & Gynecology.

Karen C. Schliep, PhD, from the Eunice Kennedy Shriver National Institute of Child Health and Human Development in Bethesda, Maryland, and colleagues compared time to pregnancy and live birth among couples with varying intervals of pregnancy loss date to subsequent trying to conceive date. 

Data were included for 1083 women aged 18 to 40 years with 1 to 2 prior early losses and whose last pregnancy outcome was a nonectopic or nonmolar loss. Participants were followed for up to 6 menstrual cycles.

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The researchers found that, compared with couples with a greater than 3-month interval, couples with a 0- to 3-month interval were more likely to achieve live birth (53.2% vs 36.1%), with a significantly shorter time to pregnancy leading to live birth (median, 5 cycles; adjusted fecundability odds ratio, 1.71). 

The estimates were not appreciably altered after adjustment for low-dose aspirin treatment.

“Our study supports the hypothesis that there is no physiologic evidence for delaying pregnancy attempt after an early loss,” the researchers wrote.


  1. Schliep KC, Mitchell EM, Mumford SL, et al. Trying to Conceive After an Early Pregnancy Loss: An Assessment on How Long Couples Should Wait. Obstet Gynecol. 2016;doi:10.1097/AOG.0000000000001159.