Androgen and Reproductive Disorders

Latest News

Novel GnRH Antagonist Reduces Heavy Menstrual Bleeding in Uterine Fibroids Study

By

Steve Duffy

Linzagolix is a novel, oral gonadotropin-releasing hormone (GnRH) receptor antagonist, the trial assessed the treatment in 535 women.

Premature Menopause Associated With Increased Long-Term Cardiovascular Risk

By

Amit Akirov, MD

Premature menopause, defined as either surgical or natural menopause before 40 years of age, is associated with an increased risk for cardiovascular disease.

Testosterone Replacement May Improve Body Composition in Male Cancer Survivors

By

Amit Akirov, MD

Testosterone replacement therapy may improve body composition in young male cancer survivors with borderline-low testosterone levels.

Cannabis May Be Effective for Endometriosis-Related Symptoms and Pain

By

Laurell Haapanen

In an online survey, women reported that cannabis was effective in reducing pain and other symptoms related to endometriosis.

Lower Education, Hepatitis C Co-Infection Linked to Earlier Menopause in HIV

By

Hannah Dellabella

In women with HIV, lower education and hepatitis C co-infection are independently associated with the onset of menopause before age 45 years.

Short-Term Testosterone Therapy Associated With VTE Risk in Men

For men with and without hypogonadism, testosterone therapy is associated with an increased short-term risk for venous thromboembolism.

Elagolix Suppresses But Does Not Consistently Inhibit Ovulation

By

Amit Akirov, MD

In healthy women with normal ovulatory function, treatment with elagolix suppressed ovulation in a dose-dependent manner and reduced endometrial thickness at doses used to treat endometriosis pain.

Anti-Müllerian Hormone a Potential Biomarker for Menstrual Disturbance in PCOS

By

Morgan E. Meissner

Findings show that anti-Müllerian hormone (AMH) is a strong predictor for menstrual disturbance due to PCOS and that the risk for menstrual disturbance was increased with the degree of elevation of AMH.

Prostate Cancer Risk Higher in Men Receiving Fertility Treatment

Men fathering children through assisted reproduction techniques rather than natural conception have an increased risk for prostate cancer, including early-onset disease.

Providing Contraception Prescriptions Online May Be a Viable Option

Telecontraception — the provision of contraception through a website or smartphone app — is feasible and seems safe for patients.

Hysterectomy Linked to Long-Term Risk for Depression, Anxiety

Hysterectomy, even with ovarian conservation, is associated with an increased long-term risk for de novo depression.