Higher Aldosterone Linked to Increased Parathyroid Hormone Levels

Higher Aldosterone Linked to Increased Parathyroid Hormone Levels
Higher Aldosterone Linked to Increased Parathyroid Hormone Levels
Higher aldosterone levels are linked to increased parathyroid hormone levels, RAAS inhibitors are associated with lower parathyroid hormone concentrations.

CONTEXT: An expanding body of evidence supports a bidirectional and positive physiologic relationship between aldosterone and PTH. Large population-based studies confirming this relationship and its potential as a treatment target are needed.

OBJECTIVE: We hypothesized that higher aldosterone levels would associate with higher PTH, and that the use of renin-angiotensin-aldosterone system (RAAS) inhibitors would predict lower PTH in a large, multi-ethnic, community-based cohort.

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