Cushing Syndrome

Latest News

Special Considerations for Patients With Cushing Syndrome and COVID-19

By

Amit Akirov, MD

Patients with Cushing syndrome are at an increased risk for infections, including severe COVID-19, due to immunodeficiency and other comorbidities.

Osilodrostat Now Available for Treatment of Patients With Cushing Disease

By

Brian Park, PharmD

Isturisa is exclusively available through the R.A.R.E.™ Patient Support Program and distributed via AnovoRx specialty pharmacy.

Novel Therapy for Cushing Disease Receives FDA Approval

By

Diana Ernst, RPh

The Food and Drug Administration (FDA) has approved Isturisa® (osilodrostat; Recordati) for the treatment of adults with Cushing disease for whom pituitary surgery is not an option or has not been curative.

No Clear Distinguishing Factors for Primary Aldosteronism Plus Subclinical Cushing Syndrome

By

Hannah Dellabella

No reference criteria can definitively distinguish patients with primary aldosteronism and subclinical Cushing syndrome from those with these conditions alone.

Levoketoconazole Effectively Treats Endogenous Cushing Syndrome in Phase 3 Trial

By

Amit Akirov, MD

According to results of the phase 3 SONICS trial, levoketoconazole is a safe and effective treatment option for patients with Cushing syndrome.

Sex Affects Clinical Presentation of ACTH-Dependent Cushing Syndrome

By

Morgan E. Meissner

Researchers examined sex differences in clinical presentation and patient outcomes in ACTH-dependent Cushing syndrome.

Signs and Symptoms of Adrenal Medullary Hyperplasia vs Pheochromocytoma

By

Hannah Dellabella

Patients with AMH without pheochromocytoma had milder symptoms compared with patients with pheochromocytoma only.

Mifepristone an Effective Alternative to Surgery for Patients With Bilateral Macronodular Adrenal Hyperplasia

By

Tyler Rice

Mifepristone may be an effective alternative to adrenalectomy in patients with hypercortisolism caused by primary bilateral macronodular adrenal hyperplasia.

Transsphenoidal Surgery Recommended for Cushing Disease With Inconclusive or Normal MRI

By

Amit Akirov, MD

In the absence of clear evidence of a pituitary adenoma on imaging, there is some controversy regarding the best treatment for Cushing disease.

High Prevalence of Diabetes in Patients With Primary Aldosteronism

By

Endocrinology Advisor Contributing Writer

Prevalence of diabetes is higher in patients with primary aldosteronism and was found to be related to suspected subclinical hypercortisolism.

New Data for Potential Cushing Syndrome Treatment Levoketoconazole Announced

By

Da Hee Han, PharmD

Researchers reported that mean urinary-free cortisol (mUFC) normalization with Recorlev was similar in patients with and without diabetes.