Adrenal

Latest News

Half of All Patients With Hypertension Should be Screened for Primary Aldosteronism

By

Amy Reyes

Patients with resistant hypertension and hypokalemia are likely to have primary aldosteronism, which may be at the root of their condition. Screening rates patients for primary aldosteronism doesn’t appear to be common practice.

Genetic Basis for PMAH Enables Earlier Diagnosis, Improves Management of Cushing Syndrome

By

Endocrinology Advisor Contributing Writer

Several research studies presented at ENDO 2021 have evaluated the molecular mechanisms underlying Cushing syndrome to facilitate earlier diagnosis and improve disease management.

Adrenal Insufficiency Associated With Increased CVD and Cerebrovascular Disease

By

Jessica Nye, PhD

Cardiovascular disease is the leading cause of death in patients with adrenal insufficiency. In this study, UK researchers weighed the presence of comorbidities against cardiovascular morbidity and mortality.

11-Hydroxytestosterone Stratifies Patients With Congenital Adrenal Hyperplasia

By

Jessica Nye, PhD

The goal of this study was to evaluate 11-oxyandrogens in discriminating good vs poor disease control in 21OHD in the setting of discrepant 17OHP and A4.

Primary Aldosteronism Testing Rare in Treatment-Resistant HTN

Patients with apparent treatment-resistant hypertension are rarely tested for primary aldosteronism.

Hydrocortisone in Granule Form Effectively Treats Childhood Adrenal Insufficiency

By

Brandon May

Hydrocortisone granules delivered accurate drug dosing to effectively treat pediatric adrenal insufficiency.

Osilodrostat Associated With Sustained Reduction of UFC in Cushing’s Disease

By

Jessica Nye, PhD

Osilodrostat treatment was found to be associated with a rapid and sustained reduction in mean concentration of urinary free cortisol and improved clinical symptoms in patients with Cushing’s disease.

Special Considerations for Patients With Cushing Syndrome and COVID-19

By

Amit Akirov, MD

Patients with Cushing syndrome are at an increased risk for infections, including severe COVID-19, due to immunodeficiency and other comorbidities.

Measuring Bone Characteristics and Derangement in Patients With Adrenal Incidentaloma

By

Amit Akirov, MD

High-resolution peripheral quantitative computed tomography can be used to assess bone abnormalities in patients with adrenal incidentaloma.

Benefits of Modified-Release Hydrocortisone for Congenital Adrenal Hyperplasia

By

Amit Akirov, MD

In patients with classical congenital adrenal hyperplasia, the use of modified-release hydrocortisone may improve biochemical control.

High Prevalence of Primary Aldosteronism Observed

Primary aldosteronism is prevalent and increases in parallel with hypertension severity.