Adrenal

Latest News

Screening for Adrenal Insufficiency in Children With Eosinophilic Esophagitis

By

Endocrinology Advisor Contributing Writer

Gastroenterologists who are members of an EoE consortia are much more likely to routinely screen for adrenal insufficiency in children with eosinophilic esophagitis who are being treated with topical corticosteroids.

No Clear Distinguishing Factors for Primary Aldosteronism Plus Subclinical Cushing Syndrome

By

Hannah Dellabella

No reference criteria can definitively distinguish patients with primary aldosteronism and subclinical Cushing syndrome from those with these conditions alone.

Pheochromocytoma, Paraganglioma May Contribute to Secondary Osteoporosis

By

Amit Akirov, MD

Pheochromocytomas and paragangliomas may be an important cause of secondary osteoporosis.

Link Between Inhaled Corticosteroids in Pediatric Asthma and Hypocortisolism

By

Virginia A. Schad, PharmD, RPh

A significantly lower hair cortisol concentration was observed in patients with asthma compared with healthy controls, suggesting that this measurement may be used to detect individuals at risk for hypocortisolism.

Levoketoconazole Effectively Treats Endogenous Cushing Syndrome in Phase 3 Trial

By

Amit Akirov, MD

According to results of the phase 3 SONICS trial, levoketoconazole is a safe and effective treatment option for patients with Cushing syndrome.

Sex Affects Clinical Presentation of ACTH-Dependent Cushing Syndrome

By

Morgan E. Meissner

Researchers examined sex differences in clinical presentation and patient outcomes in ACTH-dependent Cushing syndrome.

Increase in HDL-C, Adiponectin Levels With Glucocorticoid Replacement Therapy

By

Amit Akirov, MD

Glucocorticoid replacement therapy is associated with an increase in serum levels of adiponectin and high-density lipoprotein cholesterol.

Additional Cortisol Testing During Low-Dose ACTH Stimulation Test Can Reduce False Positives

By

Hannah Dellabella

Measuring cortisol levels at 15 and 60 minutes in addition to the standard 30 minutes can reduce false positives in standard low-dose ACTH stimulation testing with cosyntropin.

Recovery of HPA Axis Can Occur Late After Transsphenoidal Adenomectomy

By

Amit Akirov, MD

Clinicians should periodically assess patients after transsphenoidal adenomectomy given that recovery of the hypothalamus-pituitary-adrenal axis can occur as late as 12 months postsurgery.

Signs and Symptoms of Adrenal Medullary Hyperplasia vs Pheochromocytoma

By

Hannah Dellabella

Patients with AMH without pheochromocytoma had milder symptoms compared with patients with pheochromocytoma only.

Adrenal Incidentalomas Rarely Grow, Change Hormone Function

Nonfunctioning adrenal tumors (NFATs) or adenomas causing mild autonomous cortisol excess (MACE) rarely show clinically relevant changes in size or hormone function.