Adrenal

Latest News

Osilodrostat Associated With Sustained Reduction of UFC in Cushing’s Disease

By

Jessica Nye, PhD

Osilodrostat treatment was found to be associated with a rapid and sustained reduction in mean concentration of urinary free cortisol and improved clinical symptoms in patients with Cushing’s disease.

Special Considerations for Patients With Cushing Syndrome and COVID-19

By

Amit Akirov, MD

Patients with Cushing syndrome are at an increased risk for infections, including severe COVID-19, due to immunodeficiency and other comorbidities.

Measuring Bone Characteristics and Derangement in Patients With Adrenal Incidentaloma

By

Amit Akirov, MD

High-resolution peripheral quantitative computed tomography can be used to assess bone abnormalities in patients with adrenal incidentaloma.

Benefits of Modified-Release Hydrocortisone for Congenital Adrenal Hyperplasia

By

Amit Akirov, MD

In patients with classical congenital adrenal hyperplasia, the use of modified-release hydrocortisone may improve biochemical control.

High Prevalence of Primary Aldosteronism Observed

Primary aldosteronism is prevalent and increases in parallel with hypertension severity.

Osilodrostat Now Available for Treatment of Patients With Cushing Disease

By

Brian Park, PharmD

Isturisa is exclusively available through the R.A.R.E.™ Patient Support Program and distributed via AnovoRx specialty pharmacy.

Study Examines Natural History of Autoimmune Addison Disease

By

Amit Akirov, MD

In patients with autoimmune Addison disease, there is a rapid decline in steroidogenic capacity once replacement glucocorticoid medication is started.

Glucocorticoid Use, Endocrine Conditions Increase Risk in COVID-19 Infection

By

Nicole Clemons

Patients taking glucocorticoids are at a high risk if they are infected with SARS-CoV-2, according to an editorial article from the Endocrine Society.

What Causes Increased Mortality in Patients With Autoimmune Polyendocrinopathy-Candidiasis-Ectothermal Dystrophy?

By

Morgan E. Meissner

The increased mortality rate in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy is mostly related to endocrine and metabolic diseases, infections, and oral and esophageal malignancies.

Optimal Hydrocortisone Delivery Mode in Adrenal Crisis During Major Stress

By

Amit Akirov, MD

The most clinically appropriate mode of hydrocortisone administration during major stress in patients with adrenal insufficiency is continuous intravenous hydrocortisone.

Novel Therapy for Cushing Disease Receives FDA Approval

By

Diana Ernst, RPh

The Food and Drug Administration (FDA) has approved Isturisa® (osilodrostat; Recordati) for the treatment of adults with Cushing disease for whom pituitary surgery is not an option or has not been curative.