Adrenal

Latest News

Study Examines Natural History of Autoimmune Addison Disease

By

Amit Akirov, MD

In patients with autoimmune Addison disease, there is a rapid decline in steroidogenic capacity once replacement glucocorticoid medication is started.

Glucocorticoid Use, Endocrine Conditions Increase Risk in COVID-19 Infection

By

Nicole Clemons

Patients taking glucocorticoids are at a high risk if they are infected with SARS-CoV-2, according to an editorial article from the Endocrine Society.

What Causes Increased Mortality in Patients With Autoimmune Polyendocrinopathy-Candidiasis-Ectothermal Dystrophy?

By

Morgan E. Meissner

The increased mortality rate in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy is mostly related to endocrine and metabolic diseases, infections, and oral and esophageal malignancies.

Optimal Hydrocortisone Delivery Mode in Adrenal Crisis During Major Stress

By

Amit Akirov, MD

The most clinically appropriate mode of hydrocortisone administration during major stress in patients with adrenal insufficiency is continuous intravenous hydrocortisone.

Novel Therapy for Cushing Disease Receives FDA Approval

By

Diana Ernst, RPh

The Food and Drug Administration (FDA) has approved Isturisa® (osilodrostat; Recordati) for the treatment of adults with Cushing disease for whom pituitary surgery is not an option or has not been curative.

Screening for Adrenal Insufficiency in Children With Eosinophilic Esophagitis

By

Endocrinology Advisor Contributing Writer

Gastroenterologists who are members of an EoE consortia are much more likely to routinely screen for adrenal insufficiency in children with eosinophilic esophagitis who are being treated with topical corticosteroids.

No Clear Distinguishing Factors for Primary Aldosteronism Plus Subclinical Cushing Syndrome

By

Hannah Dellabella

No reference criteria can definitively distinguish patients with primary aldosteronism and subclinical Cushing syndrome from those with these conditions alone.

Pheochromocytoma, Paraganglioma May Contribute to Secondary Osteoporosis

By

Amit Akirov, MD

Pheochromocytomas and paragangliomas may be an important cause of secondary osteoporosis.

Link Between Inhaled Corticosteroids in Pediatric Asthma and Hypocortisolism

By

Virginia A. Schad, PharmD, RPh

A significantly lower hair cortisol concentration was observed in patients with asthma compared with healthy controls, suggesting that this measurement may be used to detect individuals at risk for hypocortisolism.

Levoketoconazole Effectively Treats Endogenous Cushing Syndrome in Phase 3 Trial

By

Amit Akirov, MD

According to results of the phase 3 SONICS trial, levoketoconazole is a safe and effective treatment option for patients with Cushing syndrome.

Sex Affects Clinical Presentation of ACTH-Dependent Cushing Syndrome

By

Morgan E. Meissner

Researchers examined sex differences in clinical presentation and patient outcomes in ACTH-dependent Cushing syndrome.