Plasma levels of the orexigenic neuropeptide agouti-related protein (AgRP) are elevated in Cushing disease, and it may be a marker of hypothalamic AgRP.
Researchers investigated a link between higher levels of the stress hormone cortisol and deficient memory skills in people without dementia.
The guideline highlights shared decision making among patients, their families, and physicians for the management of congenital adrenal hyperplasia.
Investigators sought to determine the frequency of metabolic syndrome in patients with nonfunctioning adrenal incidentalomas.
Results from this single-arm, open-label study found that 30% of patients achieved normalization of mean urinary free cortisol (UFC) after 6 months of maintenance treatment with levoketoconazole, without a dose increase (P<.25).
Azedra should be used by or under the control of physicians who are qualified by specific training and experience in the safe use and handling of radiopharmaceuticals.
Administering glucocorticoid leads to entrainment of molecular clocks in human peripheral blood mononuclear cells by regulating BMAL-1 and PER2-3.
Researchers assessed disease presentation and clinical outcomes in an older population of individuals with Cushing disease.
Study assessed cardiovascular function, quality of life, and mental/physical health in overt and cured Cushing syndrome.
Mechanical pain perception and somatosensory function in secondary adrenal insufficiency were examined.
The analysis led to the identification of 4 potentially pathogenic missense variants in CABLES1.