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Subclinical hypothyroidism is reportedly associated with an increased risk of adverse events in patients undergoing coronary angioplasty.
Central hypothyroidism occurs as a result of a poorly functioning thyroid stimulating hormone (TSH) that only reaches low to normal levels. In this featured study, researchers examine whether levothyroxine treatment can raise TSH levels and resolve metabolic issues.
SGLT2i use was linked to reduced mortality and morbidity in a real-world cohort of patients with heart failure and diabetes.
Study authors evaluated whether using an observational study that includes Medicare claims data could detect the proarrhythmic risk of medications known to prolong the QT interval.
Hypertensive disorders of pregnancy are associated with modestly increased risks for autism spectrum disorders and possibly ADHD in offspring.
As COVID-19 cases begin to rise again across America, President Joe Biden on Monday called on governors to bring back state mask mandates.
Existing smokers or users of electronic nicotine delivery systems (ENDS) report increased use during the initial COVID-19 lockdown.
Messenger RNA COVID-19 vaccines are effective for preventing SARS-CoV-2 infection, with 90% effectiveness for full immunization.
Observational studies using Mendelian randomization have demonstrated a causal relationship between normal range thyroid stimulating hormone (TSH) levels and blood lipids. In this featured study, researchers attempt to show a causal relationship between thyroid function and lipids.
Pediatric patients with hypothyroidism can have either positive or negative anti-thyroid antibodies, yet still exhibit signs and symptoms of hypothyroidism. In this featured study, researchers address the difference in disease status based on positive or negative test results for anti-thyroid antibodies.
The researchers sought to estimate the age-specific incidence and prevalence of dementia diagnoses among older adults with schizophrenia in the United States compared to those without serious mental illness.
Authors of the review discuss primary considerations and areas for future research regarding bisphosphonate drug holiday duration in patients with osteoporosis.
In otherwise healthy individuals, periodontitis is associated with higher systolic blood pressure.
COVID-19 lockdowns are associated with an increase in self-reported eating disorder symptoms.
Self-reported data via text messaging revealed that patients did not use about 60 percent of prescribed opioid tablets following common orthopedic or urologic procedures.
For patients with cancer, obesity is associated with worse overall and cancer-specific mortality.
In March, the Centers for Disease Control and Prevention launched phase 1c of its COVID-19 vaccine roll-out plan. Diabetes patients and patients with other underlying medical conditions are included on the list. Learn more in this article.
Excessive urination at night, or nocturia, is not uncommon in postmenopausal women. There are a number of treatment options available but with varying degrees of success.
Patients with hypothyroidism or hyperthyroidism were thought to possibly have an increased risk of developing a severe course of COVID-19 because SARS-CoV-2 uses angiotensin converting enzyme 2 (ACE2) as as an entry point for a host cell infection.
Researchers analyzed data from patients with a recent diagnosis of IE hospitalized to see whether PCT, proADM, and copeptin have prognostic value in IE compared with CRP, a known biomarker for IE.
Researchers examined the association between serum potassium concentration and outcomes in patients with heart failure with preserved ejection fraction.
Ultra-processed foods are associated with an increased risk for cardiovascular disease (CVD) incidence and mortality.
Large proportions of children with high levels of adverse childhood experiences, high distress symptoms, or both are not receiving clinical services.
The risk for having positive COVID-19 test results is 2.64-fold greater for Black individuals with a vitamin D level of 30 to 39.9 ng/mL versus a level of ≥40 ng/mL.
Current smoking is associated with an increased risk for coronary heart disease (CHD) in a cohort of African-Americans.
Patients with type 2 diabetes have an increased risk of lower-extremity amputations. In this featured study, researchers describe having developed a risk score to predict gangrene, revascularization, and amputation in patients with type 2 diabetes.
The differences in biochemical parameters of diabetic ketoacidosis in patients with end-stage kidney disease is not known, so in this featured study, researchers assess the relationship between these parameters finding significant metabolic differences.
Patients with mild heart failure whose disease stabilizes with cardiac resynchronization therapy (CRT) experience a longer survival that is similar to that observed in patients whose HF improves with CRT.
The approval was based on data from the phase 3 ODYSSEY HoFH trial, which evaluated Praluent in 69 adults with HoFH who were on other LDL-C-lowering therapies.
In new joint guidelines issued by bone health experts, recommendations are presented for managing osteoporosis therapy in the context of COVID-19 vaccination.
Black race and Hispanic ethnicity are associated with increased odds of COVID-19 positivity, although the association is substantially mediated by socioeconomic factors.
Nearly one in five high school students report relatively easy access to a handgun.
Women are are no more likely to use contraception after a diabetes diagnosis.
Patients with resistant hypertension and hypokalemia are likely to have primary aldosteronism, which may be at the root of their condition. Screening rates patients for primary aldosteronism doesn’t appear to be common practice.
Thyroidectomy is reported to be a safe and effective treatment hyperthyroidism. In this featured nonrandomized clinical trial, physicians compare the incidence of morbidity after total thyroidectomy among patients with preoperative hyperthyroidism as compared to patients with preoperative euthyroidism.
The researchers evaluated the various impacts of the concurrent COVID-19 and opioid epidemics, taking into consideration the severely restricted access to chronic pain management.
A team of researchers investigated MRI findings in association with EEG features for patients with COVID-19 and sought to better define and understand the features of COVID-19-related encephalopathy.
Increasing primary care provider density could increase life expectancy in counties with fewer PCPs per population.
Sleep problems and a high level of burnout are associated with increased odds of COVID-19 among health care workers.
Health care workers may be increasingly receptive to the COVID-19 vaccine.
Most solid organ transplant recipients do not mount an appreciable antibody response after receiving a first dose of mRNA SARS-CoV-2 vaccination.
In this study, a research team led by Gregory G. Schwartz, MD, a cardiologist with the University of Colorado School of Medicine, Aurora, examines whether diabetes is related to the concentration of lipoprotein(a) in patients with recent acute coronary syndrome and if so, whether the inhibitor alirocumab can lessen the risk of acute coronary syndrome.
It is known that elevated free fatty acid levels in obesity cause insulin resistance and as a result increase blood glucose that drives hyperinsulinemia. But what are the mechanisms that drive hyperinsulinemia and insulin resistance in obese patients?
This European study evaluated the relationship between alcohol consumption, cardiac biomarkers, and incident atrial fibrillation across the spectrum of alcohol intake.
Researchers estimated cardiovascular risk by different strategies in patients with RA; analyzed the percentage of patients who would be candidates to receive statin therapy; and identified how many patients met the recommended lipid goals.
COVID-19 vaccination coverage is higher in low compared with high social vulnerability counties across the United States.
In a move that should make reopening schools an easier task, the CDC on Friday lowered its social distancing recommendation for most classrooms to 3 feet.
Cardiovascular risk factors (CVRFs) across the life course, and especially in early adulthood, are associated with greater late-life cognitive decline.
COVID-19 is associated with increased risks for preeclampsia, preterm birth, and other adverse pregnancy outcomes.
In this clinical practice review correspondence recently published in the Journal of Clinical Endocrine and Metabolism, physicians challenge some of the standard prescribing guidance for gender affirming hormone therapy.
Achieving glycemic control is important in preventing to prevent long-term type 1 diabetes complications. In this featured study, researchers investigate the use of hybrid closed-loop automated basal insulin delivery system.
ASBMR, AACE, Endocrine Society, ECTS, IOF, and NOF developed guidance on COVID-19 vaccination and osteoporosis management.
The objective of this quasi-experimental observational study was to measure the effect of states’ hospital worker influenza vaccination laws on pneumonia and influenza mortality.
Intensive lifestyle intervention may increase the risk for cardiovascular disease for type 2 diabetes patients with overweight or obesity and poor glucose control.
Type 2 diabetes mellitus is associated with an increased risk for Parkinson disease (PD), as well as more rapid PD progression.
The percentage of postmenopausal women experiencing nocturia two or more times per night was lower among those who selected systemic hormone treatment compared with no treatment.
Children not receiving in-person school instruction and their parents have worse mental, emotional, and physical health outcomes.
Endocrinology Advisor met with Scharles Konadu, MD, a member of the American Board of Internal Medicine Gastroenterology Specialty Board, to discuss how deeply racial inequity is woven into our health care system.
Imeglimin is the first in class tetrahydrotriazine‐containing oral glucose-lowering agent Imeglimin is first in a new class of oral antidiabetic agents. In this featured phase 3 trial from France, researchers describe outcomes 107 patients with type 2 diabetes.
Previous studies have shown that continuous subcutaneous insulin infusions can lead to improvements in clinical and quality of life benefits as compared to multiple daily injections of insulin. In this study, researchers led by Sanjeev Mehta, MD, MPH, of the Joslin Diabetes Center at Harvard University, test that concept in type 1 diabetes patients.
The researchers developed a mathematical model to analyze the fundamental reason for a potential hypothalamic-pituitary-adrenal opponent process for alcohol addiction.
Patient characteristics, such as dialysis use and diabetes status, appeared to be influential factors.
Only 38.1% of adults previously diagnosed and treated for hypertension from a large population-based analysis are controlled, with CVD, migraines, diabetes, and depression associated with increased odds of control.
Moderna has launched a study of its COVID-19 vaccine in children younger than 12 years, including babies as young as 6 months.
There is an absence of online information regarding the risks of SARS-CoV-2 nasopharyngeal swab testing for patients with a history of sinus and/or pituitary surgery.
Aspirin use for cardiovascular disease prevention may also reduce the likelihood of COVID-19 infection.
Bouts of intense exercise can lead to cardiorespiratory fitness and decreased risk for cardiovascular disease in patients with type 2 diabetes.
Erythrocytosis is a side effect of testosterone therapy that can increase the risk of blood clots. In this featured study, Dutch researchers conducted a 20-year follow-up in adult trans men receiving testosterone therapy finding dangerously high hematocrit levels in some patients.
Data will be reported to the FDA by the pharmaceutical industry, health care providers, and consumers.
Researchers recommend evaluating these patients’ cornea, lens, anterior chamber volume, and anterior chamber depth.
Certain maternal dietary patterns in pregnancy are associated with differences in child body mass index trajectories from birth to adolescence.
Neither marine omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), nor vitamin D3 are associated with a reduction in the risk for incident atrial fibrillation.
Health wearable devices are effective intervention tools/strategies for reducing body weight and BMI in individuals with overweight/obesity and chronic comorbidities.
The COVID-19 pandemic has caused large disruptions to physical activity, sleep, time use, and mental health among young adults.
Risk of cancer is a major concern in the development of drugs for obesity and diabetes. In this fstudy, Brazilian researchers presenting at the annual meeting of the Endocrine Society in March, presented the results of a study that examined whether patients treated with GLP-1RAsad. a higher of breast neoplasms.
Sleep fragmentation and hypoestrogenism were shown to alter fasting nutrient utilization in this study, but not resting energy expenditure.
Hypothalamic obesity can be an acquired condition, either through a malfunctioning hypothalamus or as a result of treatment for a brain tumor.
Subclinical hypothyroidism is common patients over 70 years old, but how well older patients respond to treatment with levothyroxine (LT4) and liothyronine (LT3) is not well defined.
Proton pump inhibitors are FDA-approved for gastroesophageal reflux disease, gastric ulcers and other conditions, but not type 2 diabetes.
Universal screening for gestational diabetes is commonly accepted, but few experts agree on whether one-step or two-step screening is best.
In-hospital deaths associated with diabetic ketoacidosis have been declining in recent years, but a new analysis shows that trend was reversed in 2020 due to COVID-19.
The double-blind, placebo-controlled phase 3 study included 229 women who completed the LIBERTY long-term extension study.
As activity levels decreased during the COVID-19 pandemic, the focus of activity switched from organized sports to individualized sports such as biking and walking.
Seven in 10 US employees who started working at home during the pandemic say their companies should introduce mandatory COVID-19 vaccination before workers are called back to the office.
Among persons younger than 25 years old, racial and ethnic differences in COVID-19 incidence varied through 2020.
A patient-centered opioid discharge prescription guideline satisfies 93 percent of patients undergoing surgery.
Mortality rates of diabetes, hypertension, heart disease, and stroke are highest for Black adults living in rural areas.
Patients with type 1 and type 2 diabetes have a high risk of cardiovascular disease (CVD), but now, a new study shows that type 1 diabetes patients are more susceptible to both cardiovascular and renal disease.
Estrogens can promote breast cancer but pregnancy reduces the risk of breast cancer. In this study, researchers from the University of Massachusetts at Amherst explore whether environmental chemicals with estrogen receptor agonist properties can promote or reduce the protective effects of pregnancy on breast cancer.
This study looked at 2946 individuals without cardiovascular disease who were assessed to have intermediate ASCVD risk and underwent electrocardiography.
A team of researchers assessed mortality and neurologic outcomes in patients with lumbosacral radiculoplexus neuropathy.
Adults with higher body mass index, especially those with obesity, have an increased risk for severe outcomes in COVID-19.
A single course of teplizumab treatment delays progression to type 1 diabetes (T1D) and improves beta cell function in high-risk individuals.
Prehospitalization statin use is associated with lower inpatient mortality among patients hospitalized with COVID-19.
A one-step approach identifies more diagnoses of gestational diabetes, with no significant impact on perinatal or maternal complications.
In this featured study, researchers led by Natalie D. Shaw, MD, of the National Institutes for Environmental Health Sciences, investigate the effect of total body fat on reproductive hormone profiles and on the maturation of the estrogen-sensitive tissues (breast, uterus, urogenital epithelium, growth plates) from early/mid-puberty through menarche.his featured study, researchers led by Natalie D. Shaw, MD, of the National Institutes for Environmental Health Sciences,
Intensive behavior therapy with a low-calorie diet and regular physical activity doesn’t always lead to weight loss. In this featured clinical trial, physicians led by Thomas A. Wadden, PhD, of the University of Pennsylvania, examine the effect of once-weekly subcutaneous semaglutide as add-on therapy for weight loss.
The USPSTF recommends screening for prediabetes and type 2 diabetes in overweight or obese adults aged 35 to 70 years.
This week we have new study data on the real-world effectiveness of the Pfizer-BioNTech vaccine; The number of Americans who are completing both vaccine doses; A vaccine trial that has started in children; Approval in acute bacterial skin and skin structure infections; And results from the tocilizumab-remdesivir combo trial.
Preteens who have more screen time are more likely to develop binge-eating disorder one year later.
