This article is part of Endocrinology Advisor’s coverage of the 2017 American Society for Bone and Mineral Research (ASBMR) Annual Meeting taking place in Denver, CO. Check back regularly for more news on the latest clinical research in bone health from ASBMR 2017.

Time spent participating in light physical activity can determine the variance in femoral neck bone mineral density (BMD) in people with class III obesity, according to research presented at the 2017 American Society for Bone and Mineral Research (ASBMR) Annual Meeting, held September 8-11, 2017 in Denver, Colorado.

Researchers from the University of Porto in Portugal assessed 16 patients with class III obesity (age, 48.7±9.9 years; BMI, 47.6±1.8 kg/m2) to examine the relationship between sedentary behavior, physical activity, and BMD.

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To measure hip BMD, study participants underwent dual-energy X-ray absorptiometry (DXA) scans; physical activity and sedentary behavior were measured via accelerometer, worn for 1 week during waking hours.

During the study period, participants spent more than 694.1±79.3 minutes per day in a sedentary state and light, moderate, and vigorous physical activity for 118.7±50.3, 19.7±10.2, and 7.0±7.2 minutes per day, respectively.

No significant associations were found between sedentary time and moderate or vigorous physical activity and femoral neck BMD, and no association was found between sedentary time and physical activity for total hip BMD. Adjustments for sex, age, and BMI indicated that femoral neck BMD variability was associated with light physical activity (P =.545 for sex, .971 for age, and .750 for BMI).

“In [patients with severe obesity], femoral neck BMD variance is mostly explained by time spent in [light physical activity] and not by activities of higher intensity,” the researchers concluded.


Diniz-Sousa F, Boppre G, Machado L, et al. Influence of sedentary behavior and voluntary physical activity in bone mineral density in patients with class III obesity. Presented at: 2017 American Society for Bone and Mineral Research Annual Meeting; September 8-11, 2017; Denver, CO. Abstract SU0004.