Drug Name:
GLUCAGON Rx

Generic Name and Formulations:
Glucagon (recombinant) 1mg/mL; pwd for IM, IV, or SC inj after reconstitution.
Company:
Lilly, Eli and Company
Therapeutic Use:
Indications for GLUCAGON:
Acute hypoglycemia.
Adults and Children:
<20kg: 0.5mg or 20–30mcg/kg. ≥20kg: 1mg. If patient does not respond in 15 mins, may give 1–2 more doses.
Contraindications:
Pheochromocytoma.
Warnings/Precautions:
If ineffective, IV dextrose must be given. When patient responds, supplemental carbohydrate should be given (esp. children). Type 1 diabetics may be less responsive. History of insulinoma or pheochromocytoma. Insufficient glycogen stores (eg, starvation, adrenal insufficiency, chronic hypoglycemia). Monitor serum potassium. Pregnancy (Cat.B). Nursing mothers.
Pharmacological Class:
Antihypoglycemic.
Adverse Reactions:
GI upset, hypersensitivity reactions (urticaria, respiratory distress, hypotension).
How Supplied:
Emergency kit (1mg)—1 (w. diluent)
Indications for GLUCAGON:
Diagnostic aid in the radiologic examination of the stomach, duodenum, small bowel, and colon when diminished intestinal motility would be advantageous.
Adult:
See full labeling. Give by IV or IM inj prior to procedure. Usual range 0.25-2mg once. Stomach: 0.5mg IV or 2mg IM once. Colon: Give 10mins prior to procedure; 2mg IM once.
Children:
Not established.
Contraindications:
Pheochromocytoma.
Warnings/Precautions:
History of insulinoma or pheochromocytoma. Monitor serum potassium. Pregnancy (Cat.B). Nursing mothers.
Pharmacological Class:
Antihypoglycemic.
Adverse Reactions:
GI upset, hypersensitivity reactions (urticaria, respiratory distress, hypotension).
How Supplied:
Emergency kit (1mg)—1 (w. diluent)
Endocrinology Advisor Articles
- Soluble Klotho Levels Predictive of Kidney Failure in Type 2 Diabetes
- Clinicians May Be Overtreating Older Patients With Diabetes
- Comorbid and Pharmacologic Factors Increase Risk for Gastrointestinal Disorders in Diabetes
- Obesity Risk in Infants Born to Women With Diabetes
- Increased Risk for Mortality in People With Diabetes, CHD Taking Beta-Blockers
- Diabetes May Decrease Ability to Feel Acid Regurgitation
- Autism Does Not Affect Metabolic Control in Type 1 Diabetes
- Hormonal Contraceptives May Adversely Affect Psychological Health in Adolescent Girls
- Obesity Can Negatively Effect Liver in Children as Young as 8
- Recommendations Developed on Gender Equity in Medicine