General Endocrinology

Metabolically Healthy Obese Children, Adolescents at Higher Risk for CVD

Metabolically Healthy Obese Children, Adolescents at Higher Risk for CVD

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Children and adolescents with metabolically healthy obesity had higher carotid intima-media thickness compared with metabolically healthy individuals who were a normal weight.

Irisin Levels May Be Metabolic Biomarker for GH Replacement Therapy

Irisin Levels May Be Metabolic Biomarker for GH Replacement Therapy

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Growth hormone replacement can raise irisin levels in children with growth hormone deficiency.

ADA Issues Position Statement on Comprehensive Care for Pediatric T2D

ADA Issues Position Statement on Comprehensive Care for Pediatric T2D

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The American Diabetes Association issued a position statement outlining the recognition, management, and prevention of T2D in the pediatric population.

Normal Height Velocity Maintained With Reduced Growth Hormone Dose

Normal Height Velocity Maintained With Reduced Growth Hormone Dose

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Normal height velocity can be maintained in prepubertal children during the catch-up growth period by reducing growth hormone dosage by 50%.

An Intermediary Role for Insulin Resistance in the Adipose-Bone Mass Relationship in Adolescents

An Intermediary Role for Insulin Resistance in the Adipose-Bone Mass Relationship in Adolescents

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Insulin resistance may play an intermediary role in the relationship between adiposity and lumbar spine bone mass in adolescents.

Triponderal Mass Index Not Superior to BMI in Estimating Obesity Outcomes

Triponderal Mass Index Not Superior to BMI in Estimating Obesity Outcomes

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Triponderal mass index alone and in combination with body mass index (BMI) or subscapular skinfold thickness was not superior to BMI alone for estimating obesity-related outcomes in adulthood.

Acromegaly Outlook Improves With Better Diagnostics and Treatment

Acromegaly Outlook Improves With Better Diagnostics and Treatment

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With greater awareness, better therapeutics, and more precise imaging and biochemical assays, patients with acromegaly can be diagnosed and treated earlier and are oftentimes cured.

Trends in Metabolic, Bariatric Surgery for Pediatric Patients

Trends in Metabolic, Bariatric Surgery for Pediatric Patients

From 2005 through 2014, an estimated 14,178 metabolic and bariatric surgery (MBS) procedures were performed among pediatric patients aged 20 years and younger with severe obesity.

Pediatric Obesity Linked to Slipped Capital Femoral Epiphysis

Pediatric Obesity Linked to Slipped Capital Femoral Epiphysis

High childhood body mass index is strongly correlated with slipped capital femoral epiphysis.

Is BPA Safe? Endocrine Society Addresses FDA Position on Commercial BPA Use

Is BPA Safe? Endocrine Society Addresses FDA Position on Commercial BPA Use

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The Endocrine Society has expressed concern regarding the FDA's position on use of BPA in commercial products.

Supporting the Transition From Pediatric to Adult Health Care

Supporting the Transition From Pediatric to Adult Health Care

Guidelines have been updated to support the health care transition from adolescence to adulthood.

Predictive Variables for Permanent vs Transient Congenital Hypothyroidism

Predictive Variables for Permanent vs Transient Congenital Hypothyroidism

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Thyroid stimulating hormone levels at diagnosis and the L-thyroxine dose through treatment may distinguish between permanent and transient congenital hypothyroidism.

Early Manifestations, Sex Differences May Aid in Acromegaly Diagnosis

Early Manifestations, Sex Differences May Aid in Acromegaly Diagnosis

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Researchers described signs and symptoms in the years prior to acromegaly diagnosis and reported on differences between men and women in their clinical manifestations.

Adverse Events Associated With Diazoxide Treatment for Congenital Hyperinsulinism

Adverse Events Associated With Diazoxide Treatment for Congenital Hyperinsulinism

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Diazoxide treatment in children with congenital hyperinsulinism is associated most commonly with neutropenia, but also carries a risk for pulmonary hypertension.

Breastfeeding Inversely Associated With Weight Gain Velocity and BMI

Breastfeeding Inversely Associated With Weight Gain Velocity and BMI

Breastfeeding is inversely associated with body mass index z scores measured at 12 months, and the association is attenuated with formula supplementation by six months.

Safety and Mortality Outcomes Following Pediatric Growth Hormone Therapy

Safety and Mortality Outcomes Following Pediatric Growth Hormone Therapy

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Primary cancer rates and mortality risk were no higher for pediatric patients treated with growth hormone therapy.

Relacorilant Gets Orphan Drug Designation for Pancreatic Cancer

Relacorilant Gets Orphan Drug Designation for Pancreatic Cancer

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The Company is investigating the treatment as a combination with nab-paclitaxel (Abraxane; Celgene) for pancreatic cancers and other solid tumors.

Newer Hormonal Contraception May Reduce Ovarian Cancer Risk

Newer Hormonal Contraception May Reduce Ovarian Cancer Risk

There is a reduction in ovarian cancer risk associated with use of contemporary combined hormonal contraceptives.

Medicaid Expansion Programs Improve Women's Access to Reproductive Services

Medicaid Expansion Programs Improve Women's Access to Reproductive Services

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One-third of the women enrolled in Michigan's Medicaid expansion program reported improved access to birth control and family planning services.

Education Can Increase Emotional Intelligence in Residents

Education Can Increase Emotional Intelligence in Residents

Following an educational intervention, residents from pediatrics and med-ped residency programs have an increase in total emotional intelligence.

Risk for Hypercalciuria With Recommended Dose of Vitamin D Supplement

Risk for Hypercalciuria With Recommended Dose of Vitamin D Supplement

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The upper level of vitamin D recommended by the Endocrine Society can result in frequent hypercalciuria.

Endocrine Society Updates Congenital Adrenal Hyperplasia Clinical Practice Guidelines

Endocrine Society Updates Congenital Adrenal Hyperplasia Clinical Practice Guidelines

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The guideline highlights shared decision making among patients, their families, and physicians for the management of congenital adrenal hyperplasia.

Linking Gestational Diabetes to Maternal Glucose Metabolism, Childhood Adiposity

Linking Gestational Diabetes to Maternal Glucose Metabolism, Childhood Adiposity

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To understand the associations between exposure to gestational diabetes and the risk for maternal glucose metabolism and childhood adiposity, researchers followed a cohort of mothers and children for a median of 11.4 years.

Providers of Pediatric Care Have Role in Supporting Transgender Youth

Providers of Pediatric Care Have Role in Supporting Transgender Youth

The AAP recommends that youth who identify as TGD have access to comprehensive, gender affirming, and developmentally appropriate health care.

Perinatal Exposure to Air Pollution Linked to Newborn Thyroid Function

Perinatal Exposure to Air Pollution Linked to Newborn Thyroid Function

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Total thyroxine in newborns was measured by heel-stick blood spot test.

Adipokines Associated With Clinical Course Alteration in Pediatric Patients With T1D

Adipokines Associated With Clinical Course Alteration in Pediatric Patients With T1D

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Altered serum levels of nicotinamide phosphoribosyltransferase, omentin-1, and caspase-cleaved cytokeratin 18 fragment M30 in children with type 1 diabetes may signify metabolic differences that do not stabilize with insulin treatment.

Ivacaftor Improves Insulin Secretion in Children With Cystic Fibrosis

Ivacaftor Improves Insulin Secretion in Children With Cystic Fibrosis

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First-phase and glucose-potentiation of arginine-induced insulin secretion as assessed by acute C-peptide responses improved after the initiation of ivacaftor in children with cystic fibrosis.

Executive Function Predicts T1D Management Into Emerging Adulthood

Executive Function Predicts T1D Management Into Emerging Adulthood

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Individuals with higher executive function performance at baseline experienced slower increases in HbA1c.

Child Participation in Medicaid, CHIP Up From 2013 to 2016

Child Participation in Medicaid, CHIP Up From 2013 to 2016

From 2013 to 2016 there was an increase in children's participation in Medicaid and the Children's Health Insurance Program.

Recent Increase in Contraception Use Noted Among US Teenagers

Recent Increase in Contraception Use Noted Among US Teenagers

Increases in use of one or more contraceptive methods, dual-method use, long-acting reversibles.

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