General Endocrinology Archive

Trends in Metabolic, Bariatric Surgery for Pediatric Patients

Trends in Metabolic, Bariatric Surgery for Pediatric Patients

From 2005 through 2014, an estimated 14,178 metabolic and bariatric surgery (MBS) procedures were performed among pediatric patients aged 20 years and younger with severe obesity.

Pediatric Obesity Linked to Slipped Capital Femoral Epiphysis

Pediatric Obesity Linked to Slipped Capital Femoral Epiphysis

High childhood body mass index is strongly correlated with slipped capital femoral epiphysis.

Is BPA Safe? Endocrine Society Addresses FDA Position on Commercial BPA Use

Is BPA Safe? Endocrine Society Addresses FDA Position on Commercial BPA Use

The Endocrine Society has expressed concern regarding the FDA's position on use of BPA in commercial products.

Supporting the Transition From Pediatric to Adult Health Care

Supporting the Transition From Pediatric to Adult Health Care

Guidelines have been updated to support the health care transition from adolescence to adulthood.

Early Manifestations, Sex Differences May Aid in Acromegaly Diagnosis

Early Manifestations, Sex Differences May Aid in Acromegaly Diagnosis

Researchers described signs and symptoms in the years prior to acromegaly diagnosis and reported on differences between men and women in their clinical manifestations.

Predictive Variables for Permanent vs Transient Congenital Hypothyroidism

Predictive Variables for Permanent vs Transient Congenital Hypothyroidism

Thyroid stimulating hormone levels at diagnosis and the L-thyroxine dose through treatment may distinguish between permanent and transient congenital hypothyroidism.

Adverse Events Associated With Diazoxide Treatment for Congenital Hyperinsulinism

Adverse Events Associated With Diazoxide Treatment for Congenital Hyperinsulinism

Diazoxide treatment in children with congenital hyperinsulinism is associated most commonly with neutropenia, but also carries a risk for pulmonary hypertension.

Breastfeeding Inversely Associated With Weight Gain Velocity and BMI

Breastfeeding Inversely Associated With Weight Gain Velocity and BMI

Breastfeeding is inversely associated with body mass index z scores measured at 12 months, and the association is attenuated with formula supplementation by six months.

Safety and Mortality Outcomes Following Pediatric Growth Hormone Therapy

Safety and Mortality Outcomes Following Pediatric Growth Hormone Therapy

Primary cancer rates and mortality risk were no higher for pediatric patients treated with growth hormone therapy.

Relacorilant Gets Orphan Drug Designation for Pancreatic Cancer

Relacorilant Gets Orphan Drug Designation for Pancreatic Cancer

The Company is investigating the treatment as a combination with nab-paclitaxel (Abraxane; Celgene) for pancreatic cancers and other solid tumors.

Medicaid Expansion Programs Improve Women's Access to Reproductive Services

Medicaid Expansion Programs Improve Women's Access to Reproductive Services

One-third of the women enrolled in Michigan's Medicaid expansion program reported improved access to birth control and family planning services.

Newer Hormonal Contraception May Reduce Ovarian Cancer Risk

Newer Hormonal Contraception May Reduce Ovarian Cancer Risk

There is a reduction in ovarian cancer risk associated with use of contemporary combined hormonal contraceptives.

Education Can Increase Emotional Intelligence in Residents

Education Can Increase Emotional Intelligence in Residents

Following an educational intervention, residents from pediatrics and med-ped residency programs have an increase in total emotional intelligence.

Risk for Hypercalciuria With Recommended Dose of Vitamin D Supplement

Risk for Hypercalciuria With Recommended Dose of Vitamin D Supplement

The upper level of vitamin D recommended by the Endocrine Society can result in frequent hypercalciuria.

Endocrine Society Updates Congenital Adrenal Hyperplasia Clinical Practice Guidelines

Endocrine Society Updates Congenital Adrenal Hyperplasia Clinical Practice Guidelines

The guideline highlights shared decision making among patients, their families, and physicians for the management of congenital adrenal hyperplasia.

Linking Gestational Diabetes to Maternal Glucose Metabolism, Childhood Adiposity

Linking Gestational Diabetes to Maternal Glucose Metabolism, Childhood Adiposity

To understand the associations between exposure to gestational diabetes and the risk for maternal glucose metabolism and childhood adiposity, researchers followed a cohort of mothers and children for a median of 11.4 years.

Providers of Pediatric Care Have Role in Supporting Transgender Youth

Providers of Pediatric Care Have Role in Supporting Transgender Youth

The AAP recommends that youth who identify as TGD have access to comprehensive, gender affirming, and developmentally appropriate health care.

Adipokines Associated With Clinical Course Alteration in Pediatric Patients With T1D

Adipokines Associated With Clinical Course Alteration in Pediatric Patients With T1D

Altered serum levels of nicotinamide phosphoribosyltransferase, omentin-1, and caspase-cleaved cytokeratin 18 fragment M30 in children with type 1 diabetes may signify metabolic differences that do not stabilize with insulin treatment.

Ivacaftor Improves Insulin Secretion in Children With Cystic Fibrosis

Ivacaftor Improves Insulin Secretion in Children With Cystic Fibrosis

First-phase and glucose-potentiation of arginine-induced insulin secretion as assessed by acute C-peptide responses improved after the initiation of ivacaftor in children with cystic fibrosis.

Clonidine Testing Is Safe and Reliable for Diagnosing Growth Hormone Deficiency

Clonidine Testing Is Safe and Reliable for Diagnosing Growth Hormone Deficiency

Investigators examined the reliability of the clonidine test in children with short stature who had been evaluated for suspected growth hormone deficiency.

Executive Function Predicts T1D Management Into Emerging Adulthood

Executive Function Predicts T1D Management Into Emerging Adulthood

Individuals with higher executive function performance at baseline experienced slower increases in HbA1c.

Child Participation in Medicaid, CHIP Up From 2013 to 2016

Child Participation in Medicaid, CHIP Up From 2013 to 2016

From 2013 to 2016 there was an increase in children's participation in Medicaid and the Children's Health Insurance Program.

Recent Increase in Contraception Use Noted Among US Teenagers

Recent Increase in Contraception Use Noted Among US Teenagers

Increases in use of one or more contraceptive methods, dual-method use, long-acting reversibles.

Higher Risk for Meningioma Linked to GH Treatment, Radiotherapy During Childhood

Higher Risk for Meningioma Linked to GH Treatment, Radiotherapy During Childhood

The risk for meningioma was not significantly higher in patients who did not receive radiotherapy.

Medicaid Expansion Increases Access to Family Planning Services

Medicaid Expansion Increases Access to Family Planning Services

1 in 3 women of reproductive age report better ability to access birth control, family planning services.

Effect of Birth Weight and Rapid Weight Gain During Infancy on Insulin Sensitivity

Effect of Birth Weight and Rapid Weight Gain During Infancy on Insulin Sensitivity

Investigators sought to determine the effect of birth weight, weight gain from 0 to 2 years, and adiposity on insulin resistance and sensitivity in early adolescence.

Polycystic Ovary Syndrome May Be Associated With Autism in Offspring

Polycystic Ovary Syndrome May Be Associated With Autism in Offspring

The prenatal sex steroid theory hypothesizes that women with PCOS would have heightened autistic traits and an increased rate of autism among their children.

Grote Clinical Decision Rule May Be Best for Monitoring Growth in Children

Grote Clinical Decision Rule May Be Best for Monitoring Growth in Children

Investigators sought to improve growth-monitoring programs by examining existing algorithms and examined the effect of using WHO vs national growth charts on algorithm performance.

Pancreatic Cancer and New-Onset Diabetes

Pancreatic Cancer and New-Onset Diabetes

New-onset adult diabetes mellitus appears to be both a risk factor for and a sequelae of pancreatic cancer.

High Prevalence of Sleep Apnea in Patients With Acromegaly

High Prevalence of Sleep Apnea in Patients With Acromegaly

Sleep apnea is common in patients with acromegaly and is often diagnosed before the diagnosis of acromegaly.

Updated Consensus on Management of Acromegaly Includes New Recommendations

Updated Consensus on Management of Acromegaly Includes New Recommendations

Experts in the management of acromegaly provide new recommendations on the medical management of acromegaly since the last published update in 2014.

Pasireotide Improves IGF-1 in Patients Resistant to Somatostatin Analogs

Pasireotide Improves IGF-1 in Patients Resistant to Somatostatin Analogs

Monthly pasireotide injections may benefit patients with acromegaly who are resistant to first-generation somatostatin analogs.

Vitamin D Independently, Inversely Tied to Total, HDL, LDL Cholesterol in Children

Vitamin D Independently, Inversely Tied to Total, HDL, LDL Cholesterol in Children

Serum 25-hydroxyvitamin D [25(OH)D] is independently and inversely associated with total cholesterol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol in children.

Are Women With Polycystic Ovary Syndrome More Likely to Develop Psychiatric Disorder?

Are Women With Polycystic Ovary Syndrome More Likely to Develop Psychiatric Disorder?

Investigators observed an increased rate of obsessive compulsive disorder and somatization in women with polycystic ovary syndrome.

Counseling Needed for Pediatric Patients With Impaired Fertility

Counseling Needed for Pediatric Patients With Impaired Fertility

Counseling about impaired fertility and sexual function for at-risk pediatric populations in developmentally appropriate ways is essential.

ASMBS Pediatric Committee Updates Guidelines on Bariatric Surgery in Teens

ASMBS Pediatric Committee Updates Guidelines on Bariatric Surgery in Teens

The American Society for Metabolic and Bariatric Surgery Pediatric Committee has updated their 2012 evidence-based guidelines.

FDA Approves First Mobile App for Use in Preventing Pregnancy

FDA Approves First Mobile App for Use in Preventing Pregnancy

The algorithm was designed to account for sperm survival, variation in cycle length, ovulation day, temperature fluctuations and the length of the follicular and luteal phases of the menstrual cycle.

Cushing Syndrome Results in Poor Quality of Life Even After Remission

Cushing Syndrome Results in Poor Quality of Life Even After Remission

Although patients reach clinical and biochemical remission, patients exposed to hypercortisolism do not show functional remission.

Self-Administered Contraceptive Vaginal System Approved for Up to 1 Year of Use

Self-Administered Contraceptive Vaginal System Approved for Up to 1 Year of Use

The safety and efficacy of Annovera was evaluated in 3 open-label clinical trials involving healthy women (ages 18 to 40).

Appetite Awareness Training May Enhance Behavioral Strategies in Childhood Obesity

Appetite Awareness Training May Enhance Behavioral Strategies in Childhood Obesity

The lifestyle physical activity program included weight education, control, self-monitoring, behavioral change techniques, and maintenance of behavior change.

Two-Screen Program More Effective for Identifying Congenital Hypothyroidism

Two-Screen Program More Effective for Identifying Congenital Hypothyroidism

There are 14 states that perform a routine second screening in infants at approximately 2 weeks of age.

ADA Releases Updated Guidelines for Managing Pediatric Type 1 Diabetes

ADA Releases Updated Guidelines for Managing Pediatric Type 1 Diabetes

It is critical for us to remember that children are not little adults. Pediatric-onset diabetes is different from adult-onset diabetes due to its distinct epidemiology, pathophysiology, developmental considerations, and response to therapy.

Plasma Copeptin More Accurate for Diabetes Insipidus Diagnosis

Plasma Copeptin More Accurate for Diabetes Insipidus Diagnosis

In patients with hypotonic polyuria, the direct measurement of hypertonic saline-stimulated plasma copeptin has better diagnostic accuracy than the water-deprivation test.

Metyrapone Reduced Urinary-Free Cortisol Levels in Cushing Syndrome

Metyrapone Reduced Urinary-Free Cortisol Levels in Cushing Syndrome

The treatment goals for Cushing syndrome are to normalize cortisol levels, reverse clinical symptoms, and if possible to remove the secreting neoplasm.

International PCOS Network Issues New Guidelines for Management and Diagnosis of PCOS

International PCOS Network Issues New Guidelines for Management and Diagnosis of PCOS

International evidence-based guidelines include 166 recommendations and practice points to improve health outcomes of women with PCOS.

The Association Between Skin Diseases and Metabolic Syndrome

The Association Between Skin Diseases and Metabolic Syndrome

Investigators examine the association between various skin conditions and metabolic syndrome.

Hepatitis B Infection May Increase the Risk for Pancreatic Cancer

Hepatitis B Infection May Increase the Risk for Pancreatic Cancer

Investigators assessed the association of hepatitis B infection and pancreatic cancer, along with predictors of pancreatic cancer and mortality.

Men With Migraines May Have Increased Serum Estradiol, Androgen Deficiency

Men With Migraines May Have Increased Serum Estradiol, Androgen Deficiency

Men with migraines were found to have increased levels of estradiol and to be more likely to have relative androgen deficiency compared with men without migraines.

Young Cancer Survivors Have High Risk of Endocrine Diseases

Young Cancer Survivors Have High Risk of Endocrine Diseases

Adolescent and young adult cancer survivors have a 73 percent higher risk of endocrine diseases.

Preconception Vitamin D Concentrations and Pregnancy Outcomes

Preconception Vitamin D Concentrations and Pregnancy Outcomes

The association between preconception Vitamin D levels and pregnancy outcomes in women with previous pregnancy losses was examined.

Prevalence and Predictors of Renal Calcification in Primary Hyperparathyroidism

Prevalence and Predictors of Renal Calcification in Primary Hyperparathyroidism

Investigators aimed to assess biochemical predictors of renal calcifications in patients with primary hyperparathyroidism.

Accuracy of Diagnostic Tests for GH Deficiency in Childhood Cancer Survivors

Accuracy of Diagnostic Tests for GH Deficiency in Childhood Cancer Survivors

The utility of IGF-I and IGFBP-3 for growth hormone testing in childhood cancer survivors was examined.

Increased Risk for Early Gonadarche Associated With Oxandrolone Treatment

Increased Risk for Early Gonadarche Associated With Oxandrolone Treatment

Investigators examine the onset of puberty and testicular function in prepubertal boys treated with oxandrolone.

Cross-Sex Hormone Therapy May Raise Vascular Event Risk in Transgender Persons

Cross-Sex Hormone Therapy May Raise Vascular Event Risk in Transgender Persons

The current study sought to compare the incidence of acute cardiovascular events among transgender persons.

Effects of Menopause on Prolactinoma Treatment Outcomes Post-Dopamine Agonist Withdrawal

Effects of Menopause on Prolactinoma Treatment Outcomes Post-Dopamine Agonist Withdrawal

Serum prolactin level 6 to 12 months after dopamine agonist withdrawal may be a useful predictor for clinical outcomes in patients with prolactinoma.

Conservative Monitoring Strategy for Non-Functioning Pituitary Adenomas Evaluated

Conservative Monitoring Strategy for Non-Functioning Pituitary Adenomas Evaluated

Investigators examined whether primary conservative monitoring is a safe strategy in patients with non-functioning pituitary adenomas.

Adjunctive Aripiprazole Lowers Prolactin Levels in Women With Psychosis

Adjunctive Aripiprazole Lowers Prolactin Levels in Women With Psychosis

These data suggest that aripiprazole can be safely used in premenopausal women to treat elevated prolactin levels and prolactin-related adverse effects.

Relationship Between Estradiol Level and Mortality in Elderly Men

Relationship Between Estradiol Level and Mortality in Elderly Men

Data from a prospective cohort study were used to determine the effect of estradiol levels on all-cause and cause-specific mortality in men aged ≥65 years.

Placebo Effect of Various Female Sexual Dysfunction Drug Txs Assessed

Placebo Effect of Various Female Sexual Dysfunction Drug Txs Assessed

For this study, the authors aimed to quantify this effect by conducting a systematic review of various databases to identify studies that included a placebo arm and used Female Sexual Function Index as a clinical outcome.

ISPAD Issues Consensus Statement on Diabetic Ketoacidosis and Hyperglycemia

ISPAD Issues Consensus Statement on Diabetic Ketoacidosis and Hyperglycemia

ISPAD recommends adjustments for fluid management regarding rehydration rates in children and adolescents with diabetes ketoacidosis.

Revised Pooled Cohort Equations for CVD Risk Improve Accuracy of Estimates

Revised Pooled Cohort Equations for CVD Risk Improve Accuracy of Estimates

Investigators revised pooled cohort equations to improve clinical accuracy to predict risk for cardiovascular disease.

Many Drugs Made Available Via FDA Expanded Access Programs

Many Drugs Made Available Via FDA Expanded Access Programs

Half of meds ID'd in expanded access programs treat cancer; others for metabolic, endocrine diseases

Screening for Comorbid Conditions Not Adequate in Acromegaly

Screening for Comorbid Conditions Not Adequate in Acromegaly

Investigators examined the frequency of comorbidity screening and the frequency of comorbidities in patients with acromegaly.

Unplanned Pregnancies Prevalent Among HIV-Positive Women

Unplanned Pregnancies Prevalent Among HIV-Positive Women

Researchers examined unplanned pregnancies and contraceptive use among HIV-positive women in a cross-sectional study.

MiniMed 670G System Approved for Use in Younger Patients With T1D

MiniMed 670G System Approved for Use in Younger Patients With T1D

The MiniMed 670G system measures glucose levels every 5 minutes and automatically adjusts insulin delivery to avoid highs and lows.

Safety and Performance of Omnipod HCL for Children With Type 1 Diabetes

Safety and Performance of Omnipod HCL for Children With Type 1 Diabetes

In children with type 1 diabetes, the Omnipod hybrid closed-loop personal model system was safe and performed well.

Metabolic Health Predicative of Cognitive Development in Children

Metabolic Health Predicative of Cognitive Development in Children

Researchers assessed whether current metabolic parameters are inversely associated with cognitive functioning.

Effect of Infant Feeding Practices and Gut Microbiota on Overweight in First Year

Effect of Infant Feeding Practices and Gut Microbiota on Overweight in First Year

Researchers assessed the effect of formula supplementation vs breastfeeding on the gut microbiome and risk of infant overweight.

Reduced Mortality for Women Undergoing Assisted Reproduction Likely Due to "Healthy Patient Effect"

Reduced Mortality for Women Undergoing Assisted Reproduction Likely Due to "Healthy Patient Effect"

Researchers sought to determine whether the reduced mortality seen in women receiving reproductive assistance occurred as a result of improved general health in this population.

Timing of Serum Parathyroid Hormone Levels May Predict Postoperative Hypocalcemia

Timing of Serum Parathyroid Hormone Levels May Predict Postoperative Hypocalcemia

Serum intact parathyroid hormone levels may be an early marker to predict postthyroidectomy hypocalcemia.

Injectable Progestin-Only Contraceptives May Increase Risk for VTE

Injectable Progestin-Only Contraceptives May Increase Risk for VTE

Investigators examined the effect of progestin-only contraceptive on cardiometabolic outcomes, including stroke, MI, hypertension, diabetes, and VTE.

Hypoparathyroidism Treatment Granted Orphan Drug Designation

Hypoparathyroidism Treatment Granted Orphan Drug Designation

TransCon PTH is a long-acting prodrug of parathyroid hormone designed to restore PTH to physiologic levels, normalizing blood and urinary calcium levels, serum phosphate levels and bone turnover.

Worse Survival for BRCA Germline Mutation Carriers in Pancreatic CA

Worse Survival for BRCA Germline Mutation Carriers in Pancreatic CA

BRCA1/BRCA2 germline mutation carriers with pancreatic ductal adenocarcinoma have worse survival after resection.

Factors Associated With Decision Regret After Elective Oocyte Cryopreservation

Factors Associated With Decision Regret After Elective Oocyte Cryopreservation

Researchers identified factors associated with regret following elective oocyte cryopreservation among 201 women undergoing fertility preservation between 2012 and 2016.

LDL-C Reduction Examined With Different Evolocumab Dosing Regimens

LDL-C Reduction Examined With Different Evolocumab Dosing Regimens

For this study, researchers investigated the pharmacodynamics of evolocumab in two Phase 2 placebo-controlled studies (MENDEL and LAPLACE-TIMI 57) in order to determine which dosing regimens provided the most consistent LDL-C reduction.

Imvexxy Approved for Moderate to Severe Dyspareunia Due to Menopause

Imvexxy Approved for Moderate to Severe Dyspareunia Due to Menopause

The FDA approval was supported by findings from a Phase 3, randomized, double-blind, placebo-controlled study that evaluated Imvexxy (4mcg and 10mcg) vs placebo from baseline to week 12.

Long-Term Efficacy, Safety of Metreleptin for Generalized Lipodystrophy

Long-Term Efficacy, Safety of Metreleptin for Generalized Lipodystrophy

Investigators examined the safety and efficacy of metreleptin in patients with congenital or acquired generalized lipodystrophy.

Burosumab May Benefit Children With X-Linked Hypophosphatemia

Burosumab May Benefit Children With X-Linked Hypophosphatemia

Subcutaneous burosumab decreases mean Thacher rickets severity total score from dosing every two weeks or every four weeks.

Low Glycemic Index/Glycemic Load Decreases IGF-1 Levels in Adults With Acne

Low Glycemic Index/Glycemic Load Decreases IGF-1 Levels in Adults With Acne

Medical nutrition therapy may be a practical treatment option for patients with acne, based on the diet-induced endocrine effects on acne-promoting pathways described in this study.

Increased Risk for Type 2 Diabetes in Adolescents, Young Adults With ADHD

Increased Risk for Type 2 Diabetes in Adolescents, Young Adults With ADHD

These findings can inform clinical practice in that type 2 diabetes should be considered in ADHD even in the absence of other known risk factors.

Asthma Risk Increased for Premenopausal Women Using Oral Contraceptives

Asthma Risk Increased for Premenopausal Women Using Oral Contraceptives

Oral contraceptive use in women of reproductive age may increase the risk for lifetime asthma.

Childhood Overweight Increases Risk for Type 2 Diabetes in Adulthood

Childhood Overweight Increases Risk for Type 2 Diabetes in Adulthood

Investigators examined changes in weight from childhood to early adulthood and the risk for developing type 2 diabetes.

Glycemic Control Variations for Children, Adolescents With T1D in High-Income Countries

Glycemic Control Variations for Children, Adolescents With T1D in High-Income Countries

Investigators examined glycemic control variations in 8 high-income countries from multicenter registries in children with type 1 diabetes.

Certain Foods May Impact Timing of Menopause

Certain Foods May Impact Timing of Menopause

Researchers studied women aged 40 to 65 years participating in the UK Women's Cohort Study, who had experienced natural menopause and responded to a food frequency questionnaire.

Effect of Maternal Caffeine Intake on Childhood Growth

Effect of Maternal Caffeine Intake on Childhood Growth

Maternal caffeine intake >200 mg/day during pregnancy was associated with high weight gain velocity beginning from the first months of life and higher BMI throughout childhood.

Exceptional Glycemic Control With Very Low-Carbohydrate Diet

Exceptional Glycemic Control With Very Low-Carbohydrate Diet

For children and adults with type 1 diabetes, consuming a very low-carbohydrate diet is associated with exceptional glycemic control.

Hormonal Antiandrogen Therapy for Acne May Help Reduce Antibiotic Use

Hormonal Antiandrogen Therapy for Acne May Help Reduce Antibiotic Use

Recognizing the increased need for antibiotic stewardship, the researchers consider HAAT to be a useful alternative to systemic antibiotic therapy that is effective and well tolerated among women with inflammatory acne.

Effects of Maternal Gestational Diabetes on Neonatal Hypoglycemia: Diet vs Insulin Treatment

Effects of Maternal Gestational Diabetes on Neonatal Hypoglycemia: Diet vs Insulin Treatment

Routine screening for neonatal hypoglycemia after pregnancies complicated by gestational diabetes (GD) reveals high incidence of both mild and severe hypoglycemia for both diet-controlled and insulin-treated GD and across the full range of birth weight centiles.

Childhood Insulin Resistance Associated With Later Psychosis

Childhood Insulin Resistance Associated With Later Psychosis

The authors advised clinicians to carefully consider which antipsychotics they prescribe their patients with metabolic dysfunction, as some are known to be diabetogenic.

Mitochondrial, Muscle Ultrastructural Abnormalities Observed in Skeletal Muscle of Young Adults With T1D

Mitochondrial, Muscle Ultrastructural Abnormalities Observed in Skeletal Muscle of Young Adults With T1D

The study highlights mitochondrial and autophagic differences in the muscles of young adults with type 1 diabetes with moderate glycemic control who exceed recommended activity levels.

Risk for Iodine Deficiency and Hypothyroidism High in Children on Parenteral Nutrition

Risk for Iodine Deficiency and Hypothyroidism High in Children on Parenteral Nutrition

Study is the first to reveal a higher prevalence of iodine deficiency and hypothyroidism in children receiving chronic parenteral nutrition.

Risk for Fetal Loss Early in Pregnancy Not Greater With Noninsulin vs Insulin Therapy

Risk for Fetal Loss Early in Pregnancy Not Greater With Noninsulin vs Insulin Therapy

Compared to standard insulin treatment, noninsulin antidiabetic agents did not present an increased risk for fetal losses or major malformations when used in the first trimester of pregnancy.

Vitamin D Insufficiency Associated With Insulin Resistance Independent of Obesity in Children

Vitamin D Insufficiency Associated With Insulin Resistance Independent of Obesity in Children

Further clinical trials are needed to explore the potential beneficial effect of vitamin D supplementation, via fortified foods and/or dietary supplements, on insulin resistance, and possibly on weight management.

Factors Identified to Predict Fatty Liver in Obese Teens

Factors Identified to Predict Fatty Liver in Obese Teens

Ethnicity,race, markers of insulin resistance, and genetic factors might help identify obese youth at risk for developing fatty liver.

One-Hour Plasma Glucose Useful Predictor of Diabetic Retinopathy

One-Hour Plasma Glucose Useful Predictor of Diabetic Retinopathy

One-hour plasma glucose is a useful predictor of retinopathy risk, has a predictive value similar to that of 2-hour plasma glucose, and may be considered as an alternative glucose time point during an oral glucose tolerance test.

Young Adults With Type 1 Diabetes Show Muscle Metabolic Deficiencies

Young Adults With Type 1 Diabetes Show Muscle Metabolic Deficiencies

Physically active young adults with type 1 diabetes have alterations in mitochondrial ultrastructure and bioenergetics within skeletal muscle.

Autism Does Not Affect Metabolic Control in Type 1 Diabetes

Autism Does Not Affect Metabolic Control in Type 1 Diabetes

Awareness of ASD and its manifestations and comorbidities remain imperative in the treatment of T1D, as both conditions require long-term medical follow-up to continue improving diabetes care and metabolic control outcomes.

Hormonal Contraceptives May Adversely Affect Psychological Health in Adolescent Girls

Hormonal Contraceptives May Adversely Affect Psychological Health in Adolescent Girls

This finding suggests an adverse effect of hormonal contraception on psychological health in adolescent girls.

Obesity Can Negatively Effect Liver in Children as Young as 8

Obesity Can Negatively Effect Liver in Children as Young as 8

Researchers examined the relationship between early to mid-childhood adiposity measures and mid-childhood alanine aminotransferase levels.

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