Generic Name and Formulations:
Felodipine 2.5mg, 5mg, 10mg; ext rel tabs.
Various generic manufacturers
Indications for Felodipine:
Take without food or with a light meal. Do not crush or chew. Initially 5mg once daily. Range 2.5–10mg once daily. Adjust at 2 week intervals; max 10mg daily. Elderly or hepatic dysfunction: initially 2.5mg once daily.
Heart failure. Hepatic impairment. Maintain good dental hygiene. Elderly. Pregnancy (Cat.C). Nursing mothers: not recommended.
May increase metoprolol, tacrolimus levels. Potentiated by cimetidine. Increased bioavailability with grapefruit juice. Levels decreased with long-term anticonvulsants (eg, carbamazepine, phenytoin, phenobarbital), consider alternate antihypertensive therapy.
Calcium channel blocker (CCB) (dihydropyridine).
Peripheral edema, headache, flushing, dizziness, respiratory symptoms, weakness, cough, GI upset, gynecomastia; hypotension, tachycardia, syncope, MI, angina, gingival hyperplasia (rare).
Formerly known under the brand name Plendil.
Endocrinology Advisor Articles
- Effect of HbA1c and Perioperative Glucose on Postoperative Mortality
- GLP-1 Agonists Superior to DPP-4 Inhibitors for Reducing HbA1c, Weight in T2D
- Effect of Growth Hormone Treatment on BMD in Adults With Prader-Willi Syndrome
- Case for Continuous Glucose Monitoring in Youth-Onset Type 2 Diabetes
- Telemedicine Expands Access to Rural, Low-Income, Isolated Communities
- American College of Physicians Releases 4 Guidelines for HbA1c Targets in T2D
- Dyslipidemia Drug Indications
- No Difference in Weight Loss Outcomes With Low-Fat vs Low-Carbohydrate Diet
- Damaging Effects of Gastric Bypass Surgery on Bone Mass and Microarchitecture
- Pioglitazone May Reduce Cardiovascular, Noncardiovascular Mortality in T2D
- Once-Daily Oral Contraceptive for Men Shows Promise
- MiniMed 670G System Improves Glycemic Outcomes in Children With T1D
- Semaglutide May Be Useful for Treating Obesity in People Without Diabetes
- Low Sperm Count Linked to Poor Metabolic, Cardiovascular, Bone Health
- Estrogen Improves Eating Behavior, Psychopathology in Oligo-Amenorrheic Athletes