Drug Name:
EVISTA Rx
Generic Name and Formulations:
Raloxifene HCl 60mg; tabs.
Company:
Lilly, Eli and Company
Therapeutic Use:
Indications for EVISTA:
Prevention and treatment of osteoporosis in postmenopausal women.
Adult:
60mg once daily.
Children:
Not recommended.
Contraindications:
Active or history of venous thromboembolic events. Nursing mothers. Pregnancy (Cat.X). Women who may become pregnant.
Warnings/Precautions:
Not for use in premenopausal women. Concomitant systemic estrogen therapy: not recommended. Discontinue 72 hours before, and during prolonged immobilization; resume when fully ambulatory. Coronary heart disease or risk of coronary event (increased risk of death due to stroke). Hepatic dysfunction. Moderate to severe renal impairment.
Pharmacological Class:
Selective estrogen receptor modulator (SERM).
Interactions:
May antagonize warfarin; monitor. Avoid concomitant cholestyramine, other anion exchange resins. Caution with other highly protein-bound drugs (eg, diazepam, diazoxide, lidocaine).
Adverse Reactions:
Hot flashes, leg cramps, peripheral edema, flu syndrome, arthralgia, sweating; rare: venous thromboembolic events.
How Supplied:
Tabs—30, 100, 2000
Indications for EVISTA:
Reduction in risk of invasive breast cancer in postmenopausal women: with osteoporosis and/or at high risk for invasive breast cancer.
Adult:
60mg once daily.
Children:
Not recommended.
Contraindications:
Active or history of venous thromboembolic events. Nursing mothers. Pregnancy (Cat.X). Women who may become pregnant.
Warnings/Precautions:
Not for use in premenopausal women. Concomitant systemic estrogen therapy: not recommended. Discontinue 72 hours before, and during prolonged immobilization; resume when fully ambulatory. Coronary heart disease or risk of coronary event (increased risk of death due to stroke). Hepatic dysfunction. Moderate to severe renal impairment.
Pharmacological Class:
Selective estrogen receptor modulator (SERM).
Interactions:
May antagonize warfarin; monitor. Avoid concomitant cholestyramine, other anion exchange resins. Caution with other highly protein-bound drugs (eg, diazepam, diazoxide, lidocaine).
Adverse Reactions:
Hot flashes, leg cramps, peripheral edema, flu syndrome, arthralgia, sweating; rare: venous thromboembolic events.
How Supplied:
Tabs—30, 100, 2000
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