Indications for VICTOZA:

As adjunct to diet and exercise, to improve glycemic control in adults with type 2 diabetes mellitus (T2DM). To reduce the risk of major adverse CV events (eg, CV death, non-fatal MI/stroke) in adults with T2DM and established CV disease.

Limitations of Use:

Not a substitute for insulin. Not for treating type 1 diabetes or diabetic ketoacidosis. Not studied in combination with prandial insulin.


Give by SC inj in abdomen, thigh, or upper arm once daily. Initially 0.6mg/day for 1 week, then 1.2mg/day; may increase to 1.8mg/day. If >3 days elapsed since last dose, reinitiate at 0.6mg/day, then titrate.


<18yrs: not recommended.


History (personal or family) of medullary thyroid carcinoma. Multiple endocrine neoplasia syndrome type 2.

Boxed Warning:

Risk of thyroid C-cell tumors.


Risk of thyroid C-cell tumors; inform patients of potential risk and symptoms. Discontinue if pancreatitis is suspected; do not restart if confirmed. History of pancreatitis: limited data. Evaluate if cholelithiasis is suspected. Do not reuse or share pens or needles between patients. History of anaphylaxis or angioedema with other GLP-1 receptor agonist. Discontinue if hypersensitivity reactions occur. Renal impairment: caution with initiating or escalating doses. Hepatic impairment: use with caution (limited data). Dehydration. Gastroparesis: not studied. Pregnancy. Nursing mothers.

Pharmacologic Class:

Glucagon-like peptide-1 (GLP-1) receptor agonist.


Concomitant insulin; administer as separate injections not adjacent to each other. Hypoglycemia with sulfonylureas or insulin (consider reducing their doses). May affect absorption of concomitant oral drugs (delayed gastric emptying); caution.

Adverse Reactions:

Nausea, diarrhea, headache, vomiting, decreased appetite, dyspepsia, constipation, immunogenicity reactions (eg, urticaria); rare: pancreatitis, papillary thyroid carcinoma, hypersensitivity reactions.

Generic Availability:


How Supplied:

Multi-dose, pre-filled pens (3mL)—2, 3

Pricing for VICTOZA

3 pens of 18mg/3ml carton (Qty: 1)
Appx. price $921