LUPRON DEPOT-PED 3 MONTH Rx

Pituitary disorders:

Indications for: LUPRON DEPOT-PED 3 MONTH

Central precocious puberty.

Adult Dosage:

Not applicable.

Children Dosage:

<1yr: not established. ≥1yrs: 11.25mg or 30mg as a single IM inj once every 3 months into the gluteal area, anterior thigh, or shoulder; rotate inj sites. If inadequate response, consider other alternative treatments.

LUPRON DEPOT-PED 3 MONTH Contraindications:

Pregnancy.

LUPRON DEPOT-PED 3 MONTH Warnings/Precautions:

Must be administered by a healthcare professional. Initial transient rise in gonadotropins and sex steroids may result in increased signs/symptoms of puberty. Monitor LH and sex steroid levels at 1–2 months after treatment initiation, with dose changes, and as clinically indicated; for Depot 3-Month: monitor at months 2–3, month 6 and as needed thereafter. Measure height and bone age velocity every 6–12 months. Monitor for pseudotumor cerebri or psychiatric symptoms. History of seizures/epilepsy, cerebrovascular disorders, CNS anomalies or tumors: risk of convulsions. Exclude pregnancy prior to initiation. Advise females of reproductive potential to use non-hormonal method of contraception during treatment. Nursing mothers.

See Also:

LUPRON DEPOT-PED 3 MONTH Classification:

GnRH analogue.

LUPRON DEPOT-PED 3 MONTH Interactions:

Caution with concomitant drugs that are associated with convulsions (eg, bupropion, SSRIs).

Adverse Reactions:

Transient exacerbation of symptoms, inj site reactions, pain, headache, emotional lability, acne/seborrhea, rash, vaginitis, vaginal discharge, syncope, GI upset, gynecomastia, weight increased, mood altered.

How Supplied:

Depot-PED kit—1 (prefilled dual-chamber syringe w. diluent, supplies); Depot-PED 3 Month kit—1 (prefilled dual-chamber syringe w. diluent, supplies)