Indications for Griseofulvin:
Ringworm infections of the skin, hair, and nails.
500mg daily; max 1g daily.
30–50lbs: 125–250mg daily. Over 50lbs: 250–500mg daily.
Porphyria. Hepatocellular failure. Pregnancy.
Continue therapy until infection is eradicated. Periodic monitoring of renal, hepatic, and hematopoietic functions. Discontinue if granulocytopenia occurs. Penicillin sensitivity. Avoid exposure to sunlight or UV light. Nursing mothers.
Antagonizes oral contraceptives, oral anticoagulants. Antagonized by barbiturates.
Oral thrush, GI distress, dizziness, confusion, peripheral neuritis, photosensitivity, granulocytopenia, leukopenia, proteinuria, lupus-like syndrome.