Indications for: GELSYN-3
Treatment of pain in osteoarthritis of the knee in patients who have failed nonpharmacologic therapy and simple analgesics (eg, acetaminophen).
Remove synovial fluid or effusion before inj. Give as a single intra-articular inj. >21yrs: 2mL in one knee only at weekly intervals for 3 weeks.
≤21yrs: not established.
Knee joint infections. Skin diseases or infections in area of the inj site.
Do not inject by intravascular route. Severe intra-articular effusion. Lymphatic or venous stasis in leg. Advise patients to avoid strenuous or prolonged weight-bearing activities for approx. 48hrs following inj. Pregnancy, nursing mothers: not established.
Avoid use of disinfectants containing quaternary ammonium salts; hyaluronan can precipitate in their presence. Concomitant other intra-articular inj: not studied.
Inj site pain, arthralgia, joint effusion/warmth/stiffness/swelling, arthritis, gait disturbance, arthropathy.
Generic Drug Availability:
Single-use pre-filled syringe—1 (w. needle)