• Asthma/COPD

Asthma/COPD:

Indications for COMBIVENT RESPIMAT:

COPD when a second aerosol bronchodilator is needed.

Adult:

1 inh 4 times daily; max 6 inh/day.

Children:

Not established.

Contraindications:

Atropine allergy.

Warnings/Precautions:

Avoid excessive use. Discontinue if paradoxical bronchospasm occurs. Cardiovascular disorders. Arrhythmias. Hypertension. Diabetes. Hyperthyroidism. Seizure disorders. Sensitivity to sympthomimetic amines. Narrow angle glaucoma. GI or GU obstruction. Hepatic or renal disease. Pregnancy (Cat. C). Labor & delivery. Nursing mothers: not recommended.

Pharmacologic Class:

Anticholinergic + beta-2 agonist.

Interactions:

Extreme caution within 2 weeks of MAOIs or tricyclic antidepressants (increased cardiovascular effects). Caution with other anticholinergics, sympathomimetics, drugs that lower serum potassium. Antagonized by beta-blockers.

Adverse Reactions:

Upper respiratory infection, nasopharyngitis, cough, bronchitis, headache, dyspnea; paradoxical bronchospasm, urinary retention, hypokalemia, hypersensitivity reactions, ocular effects.

Elimination:

Ipratropium bromide: renal.

Generic Availability:

NO

How Supplied:

Inhaler—4g (120 inh)