Although the incidence of severe hypoglycemia has decreased while insulin pump use has increased, a causal relationship has not been established between insulin administration methods and risk of complications from diabetes.
Diabetic ketoacidosis led to fatal demise, preterm birth, and neonatal intensive care unit admissions.
Patients with type 2 diabetes who took sodium-glucose cotransporter 2 inhibitors were twice as likely to develop diabetic ketoacidosis than those who took dipeptidyl peptidase-4 inhibitors.
Implementation of clinical practice guidelines can reduce the length of hospitalizations among children experiencing diabetic ketoacidosis.
For patients with new-onset diabetic ketoacidosis and severe hyperglycemia, metformin and sitagliptin treatment after normoglycemia remission correlate with increased relapse-free survival and prolonged remission.
Young patients with very high HbA1c levels with recurrent diabetic ketoacidosis had a higher risk of mortality.
A program focused on behavior reduced costs and improved glycemic control in children with repeat hospitalizations for diabetic ketoacidosis.
Compared with standard protocol, patients achieved faster resolution of acidosis and hyperglycemia.
Diabetic ketoacidosis should be considered in patients with type 2 diabetes who present soon after bariatric surgery.
Expert panel recommends continued use of SGLT2 inhibitors, as risk for DKA is low.
Jennifer N. Clements, PharmD, BPCS, CDE, BCACP, reviews some details of the reports of ketocacidosis with the use of SGLT2 inhibitors.
Patients with type 2 diabetes who took canagliflozin have low incidence of serious adverse DKA events.
The FDA has issued a warning about the risk for ketoacidosis with the use of SGLT2 inhibitors, which are indicated for the treatment of type 2 diabetes.
The incidence of diabetic ketoacidosis in children in Colorado at the time of type 1 diabetes diagnosis increased by 55% from 1998 to 2012.
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