Bacillus Calmette-Guerin vaccination impacted blood sugar levels in T1D by causing a systemic shift in glucose metabolism from oxidative phosphorylation to aerobic glycolysis.
Patients with diabetes have increased mortality due to suicide, alcohol-related causes, and accidents than those without diabetes.
Researchers analyzed how improvements in metabolic syndrome may impact the risk of developing type 2 diabetes and cardiovascular disease in patients with prediabetes.
The artificial intelligence-based deep learning algorithm shows robust performance in the detection of vision-threatening referable diabetic retinopathy.
A growing body of research highlights the important role of bone in glucose metabolism.
Medically supervised, therapeutic fasting regimens can help reverse type 2 diabetes (T2D) and minimize the need for pharmacological interventions.
WHO guidelines recommend selecting sulfonylureas as the single best second-line agent for Type 2 Diabetes Mellitus (T2DM) patients.
Quick Take: Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trialOctober 16, 2018
Glucagon-like peptide-1 (GLP-1) potentiates the release of insulin from pancreatic beta cells in a glucose-dependent manner.
Quick Take: Effect of lorcaserin on prevention and remission of type 2 diabetes in overweight and obese patients (CAMELLIA-TIMI 61): a randomized, placebo-controlled trialOctober 16, 2018
There is a strong relationship between body weight and the risk of developing diabetes.
There was an association between high maternal intake of gluten and an elevated risk for type 1 diabetes for the child.
Among U.S. women, a normally high circulating prolactin concentration is associated with a reduced risk for type 2 diabetes.
Improving evidence-based decision making capacity within local health departments can lead to increased offering of evidence-based interventions for diabetes management.
In many cases, insulin was exposed to temperatures outside the recommended range, especially when refrigerated.
Osteoarthritis was the most common form of arthritis in patients with diabetes but rheumatoid arthritis had the most pronounced association with diabetes.
Study results indicated that sitagliptin showed greater glycemic efficacy than dapagliflozin treatment.
For patients with type 2 diabetes and existing cardiovascular disease, albiglutide results in fewer cardiovascular events.
For this analysis, the authors used follow-up data from all 7020 patients included in the EMPA-REG OUTCOME trial to estimate the effect of empagliflozin on all-cause mortality vs placebo over the duration of a patient's lifetime.
For patients with type 2 diabetes and acute coronary syndrome, lixisenatide can slow or prevent damage to the kidneys.
In this new analysis, researchers looked at the long-term effects of the drug on diabetes prevention and remission in these patients.
Recommendations in the report highlight the importance of patient-centered decision making for glycemic management and improving diet and exercise for patients with T2D.
The EASE Phase 3 program included 2 double-blind, placebo-controlled trials investigating the efficacy and safety of empagliflozin as an adjunct to insulin therapy in adults with type 1 diabetes.
High average glycated hemoglobin levels during the first two years after type 1 diabetes onset predict higher risk for psychiatric diagnoses.
For patients with suboptimally controlled type 1 diabetes, day-and-night hybrid closed-loop insulin delivery improves glucose control compared with sensor-augmented pump therapy.
Primary cancer rates and mortality risk were no higher for pediatric patients treated with growth hormone therapy.
Standard pen needles have an outer cover and removable inner needle cover, while safety pen needles have an outer cover and a fixed inner needle shield that is not removed before an injection.
Combination therapies of basal insulin with either vildagliptin or lixisenatide are similarly effective at producing glycemic control improvements.
Clusters of type 2 diabetes loci and traits have been identified.
Many countries are falling short on targets to reduce mortality from non-communicable diseases.
Coadministration of 24 hours of fixed-ratio pramlintide and regular human insulin improves postprandial hyperglycemia and glycemic variability in patients with type 1 diabetes.
SGLT2 inhibitors were associated with an approximately 3-fold higher risk for developing genital infections.
Endocrinology Advisor Articles
- Heritability of BMI Stronger in Obesogenic Environments
- Maternal Gluten Intake Associated With Risk for Type 1 Diabetes in Offspring
- Bone-Derived Factors in the Treatment of Diabetes
- Deep Learning Algorithm Efficiently Detects Vision-Threatening Diabetic Retinopathy
- Thyroid Hormone Therapy Not Beneficial for Subclinical Hypothyroidism
- Bacillus Calmette-Guerin Vaccination Lowers HbA1c in Type 1 Diabetes
- Early Manifestations, Sex Differences May Aid in Acromegaly Diagnosis
- Predictive Variables for Permanent vs Transient Congenital Hypothyroidism
- Aetna-CVS Merger Approved
- The Progression of Health Care From Personalized Medicine to Wellness Genomics and Beyond