Diabetes Archive

Endocrine Society: Policy and Practice Changes Necessary to Improve Access to Insulin

Endocrine Society: Policy and Practice Changes Necessary to Improve Access to Insulin

The rising cost of insulin has made it increasingly difficult for patients with diabetes to receive affordable, life-saving medication, especially patients from low-income backgrounds, patients with high deductibles, and uninsured patients.

Plasma Acylcarnitines May Indicate Risk for Type 2 Diabetes

Plasma Acylcarnitines May Indicate Risk for Type 2 Diabetes

Among individuals at a high risk for cardiovascular disease, a panel of short- and long-chain acylcarnitines was significantly associated with the incidence of type 2 diabetes.

Elevated Triglyceride Levels Affect Glycemic Control in Type 2 Diabetes

Elevated Triglyceride Levels Affect Glycemic Control in Type 2 Diabetes

Reducing triglyceride levels in patients with type 2 diabetes may help them attain more optimal glycemic control.

Large For Gestational Age a Strong Predictor of Overweight, Obesity in Childhood

Large For Gestational Age a Strong Predictor of Overweight, Obesity in Childhood

Large for gestational age (LGA) is a stronger marker than maternal diabetes for subsequently being overweight or obese in early childhood.

Sharp Increase in Projected Global Insulin Use From 2018 to 2030

Sharp Increase in Projected Global Insulin Use From 2018 to 2030

From 2018 to 2030, the insulin required to treat type 2 diabetes is expected to increase more than 20 percent.

Ezetimibe Plus Statin Therapy Reduces Ischemic Risk in Polyvascular Disease, T2D

Ezetimibe Plus Statin Therapy Reduces Ischemic Risk in Polyvascular Disease, T2D

The addition of ezetimibe to simvastatin reduced ischemic risk compared with placebo, with consistent relative risk reductions in patients with and without polyvascular disease.

Digital Obesity Treatment in Primary Care May Help Disadvantaged Patients

Digital Obesity Treatment in Primary Care May Help Disadvantaged Patients

Socioeconomically challenged patients with obesity and elevated cardiovascular risk may benefit from digital obesity treatment combined with health system resources.

Ultrasound of Deltoid Muscle May Predict Diabetes

Ultrasound of Deltoid Muscle May Predict Diabetes

The ultrasound appearance of an echogenic deltoid muscle may predict diabetes and prediabetes.

ACC Releases Recommendations for Treatment of Patients With T2D and ASCVD

ACC Releases Recommendations for Treatment of Patients With T2D and ASCVD

The American College of Cardiology published an expert consensus statement regarding decision considerations for novel cardiovascular risk reduction therapies in patients with type 2 diabetes and atherosclerotic cardiovascular disease.

Type 1 Diabetes Confers Extra Risk for Autoimmune Diseases

Type 1 Diabetes Confers Extra Risk for Autoimmune Diseases

Type 1 diabetes predisposes children and adults to autoimmune diseases, which can impair glucose metabolism and interfere with insulin therapy.

Coronary Bypass Grafting Superior to Percutaneous Coronary Intervention With Drug-Eluting Stents for Reducing Mortality in Diabetes

Coronary Bypass Grafting Superior to Percutaneous Coronary Intervention With Drug-Eluting Stents for Reducing Mortality in Diabetes

Coronary artery bypass grafting may be a superior revascularization strategy in patients with diabetes and multivessel disease.

Lifestyle Intervention Program Reduces Diabetes, Metabolic Syndrome Risk

Lifestyle Intervention Program Reduces Diabetes, Metabolic Syndrome Risk

A 12-month interdisciplinary lifestyle intervention program for prediabetic and obese patients was found to significantly reduce the risk for development of diabetes and metabolic syndrome.

Lixisenatide Associated With Beneficial Renal Outcomes in Patients With T2D

Lixisenatide Associated With Beneficial Renal Outcomes in Patients With T2D

In patients with T2D and acute coronary syndrome, treatment with the short-acting glucagon-like peptide-1 (GLP-1) receptor agonist lixisenatide reduced urinary albumin-to-creatinine ratio.

Empagliflozin Effectively Reduces Risk for Heart Failure Hospitalization

Empagliflozin Effectively Reduces Risk for Heart Failure Hospitalization

Approximately 50% of deaths in people with type 2 diabetes worldwide, and approximately two-thirds of deaths in people with type 2 diabetes in the US are caused by cardiovascular disease.

Ketogenic Diet for the Management of T2D and Associated Long-Term Complications

Ketogenic Diet for the Management of T2D and Associated Long-Term Complications

With obesity reaching epidemic proportions, and its known association with many metabolic disorders such as type 2 diabetes, dyslipidemia, hypertension, and atherosclerosis, it is worthwhile to look at nutritional approaches to managing these chronic conditions.

Noninferior CV Outcomes for Linagliptin in T2D With High CV, Renal Risk

Noninferior CV Outcomes for Linagliptin in T2D With High CV, Renal Risk

Linagliptin added to usual care compared with placebo added to usual care resulted in a noninferior risk for a composite cardiovascular or renal outcome over a median 2.2 years.

AMA, CDC Launch Campaign to Raise Awareness About Prediabetes

AMA, CDC Launch Campaign to Raise Awareness About Prediabetes

More than one-third of Americans have prediabetes, but 90 percent of them do not know they have it.

Exposure to Maternal Diabetes Increases Risk for ADHD in Offspring

Exposure to Maternal Diabetes Increases Risk for ADHD in Offspring

The 3 main types of diabetes during pregnancy were associated with offspring ADHD risk in a hierarchical order.

High Circulating Prolactin Concentrations May Lower Risk for Type 2 Diabetes

High Circulating Prolactin Concentrations May Lower Risk for Type 2 Diabetes

High circulating total prolactin concentrations may be linked with a lower risk for type 2 diabetes in women.

Dapagliflozin Lowers Heart Failure Hospitalization Rates in High-Risk Patients With Diabetes

Dapagliflozin Lowers Heart Failure Hospitalization Rates in High-Risk Patients With Diabetes

Dapagliflozin was not associated with either a higher or lower rate of MACE compared with placebo in patients with type 2 diabetes who had or were at risk for atherosclerotic cardiovascular disease.

Direct-Acting Antiviral Therapy Reduced Risk for Incident T2D in Patients With Hepatitis C Infection

Direct-Acting Antiviral Therapy Reduced Risk for Incident T2D in Patients With Hepatitis C Infection

The study compared US administrative claims data of HCV patients with ≥12 weeks of dispensed DAA therapy (N = 17,848) to untreated HCV patients with follow-up data (N = 108,350).

ADA Issues Position Statement on Comprehensive Care for Pediatric T2D

ADA Issues Position Statement on Comprehensive Care for Pediatric T2D

The American Diabetes Association issued a position statement outlining the recognition, management, and prevention of T2D in the pediatric population.

Peer Support Reduces Hospitalizations in People With Diabetes and Depression

Peer Support Reduces Hospitalizations in People With Diabetes and Depression

Patients with diabetes and depressive symptoms who received community-based peer support for diabetes management reported less frequent acute care visits and hospitalizations than patients with diabetes without depressive symptoms.

HbA1c Variability in General Population Increases Risk for Cardiovascular Events, All-Cause Mortality

HbA1c Variability in General Population Increases Risk for Cardiovascular Events, All-Cause Mortality

People who do not have diabetes or cardiovascular disease but have high hemoglobin A1c variability tend to be at greater risk for major adverse cardiovascular events and all-cause mortality.

Multiple Daily Injections vs Insulin Pump Therapy in Pregnant Women With T1D

Multiple Daily Injections vs Insulin Pump Therapy in Pregnant Women With T1D

Pregnant women with T1D who received MDI therapy had a larger decrease in HbA1c levels and were less likely to report gestational hypertension, neonatal hypoglycemia, and NICU admissions than women who used insulin pump therapy during pregnancy.

Pathogenesis of Postprandial Hypoglycemia After Roux-en-Y Gastric Bypass in T2D

Pathogenesis of Postprandial Hypoglycemia After Roux-en-Y Gastric Bypass in T2D

Postprandial hypoglycemia may occur after Roux-en-Y gastric bypass in patients with type 2 diabetes, independent from diabetes remission.

Empagliflozin Effectively Reduces Risk for Heart Failure Hospitalization in T2D

Empagliflozin Effectively Reduces Risk for Heart Failure Hospitalization in T2D

Approximately 50% of deaths in people with type 2 diabetes worldwide, and approximately two-thirds of deaths in people with type 2 diabetes in the US are caused by cardiovascular disease.

Measuring Time in Range During CGM May Be Useful Outcome Metric for Clinical Trials

Measuring Time in Range During CGM May Be Useful Outcome Metric for Clinical Trials

TIR is strongly associated with the risk of microvascular complications and should be an acceptable end point for clinical trials.

Prevalence of Arthritis in Adults With Prediabetes

Prevalence of Arthritis in Adults With Prediabetes

About 1 in 3 adults with prediabetes has arthritis, and half of those with both conditions are physically inactive and/or obese.

Acute and Persistent Prothrombic Effects Observed With Antecedent Hypoglycemia in T2D

Acute and Persistent Prothrombic Effects Observed With Antecedent Hypoglycemia in T2D

Hypoglycemia was associated with early and late prothrombotic changes in the fibrin network in individuals with type 2 diabetes.

Insulins

Insulin products chart with pharmacokinetic properties.

Insulin Administration

Insulin preparations categorized by rapid-, short-, intermediate- and long-acting. Information such as the route, administration as well as the mixing of insulins is provided.

Patients With T2D and Sickle-Cell Trait at Higher Risk for Complications

Patients With T2D and Sickle-Cell Trait at Higher Risk for Complications

Diabetic complications were more prevalent in patients with both sickle-cell trait and T2D than in patients with T2D alone.

AHA, ADA Announce Joint Education Initiative to Reduce CVD Deaths in T2D

AHA, ADA Announce Joint Education Initiative to Reduce CVD Deaths in T2D

The ADA and the AHA launch a long-term awareness and education initiative for the prevention of deaths due to cardiovascular complications in patients with T2D.

Long-Term Efficacy and Safety of Dapagliflozin for Type 1 Diabetes

Long-Term Efficacy and Safety of Dapagliflozin for Type 1 Diabetes

After 52 weeks, dapagliflozin was well tolerated and led to a clinically relevant improvement in glycemic control and weight loss without additional risk for hypoglycemia.

Type 2 Diabetes May Have Adverse Effect on Parkinson Disease Symptoms, Outcomes

Type 2 Diabetes May Have Adverse Effect on Parkinson Disease Symptoms, Outcomes

Patients with both Parkinson disease and type 2 diabetes were more likely to have cardiovascular comorbidities than those with only Parkinson disease.

Hypoglycemia Following Antifungal Treatment in Patient With Type 1 Diabetes

Hypoglycemia Following Antifungal Treatment in Patient With Type 1 Diabetes

"This is the first report of decreased insulin requirements in a patient with [T1D] correlating with micafungin administration," noted the authors.

Risk for T2D Increases Following Total or Partial Colectomy

Risk for T2D Increases Following Total or Partial Colectomy

Patients who have the entire or left side of the colon removed show increased risk for developing type 2 diabetes in the 18 years following surgery.

Undiagnosed Prediabetes Prevalent in Men With Primary Infertility

Undiagnosed Prediabetes Prevalent in Men With Primary Infertility

Approximately 15% of men experiencing infertility may have undiagnosed prediabetes.

Plant-Based Diets Beneficial for Adults With Type 2 Diabetes

Plant-Based Diets Beneficial for Adults With Type 2 Diabetes

For adults with type 2 diabetes, plant-based diets can improve psychological health, quality of life, hemoglobin A1c levels, and weight.

Lipidome Profiles Stratify Risk for Type 2 Diabetes

Lipidome Profiles Stratify Risk for Type 2 Diabetes

Early detection of lipidome characteristics could help identify the early onset of type 2 diabetes.

Diabetes Education Week 2018: Patient Resources for Your Practice

Diabetes Education Week 2018: Patient Resources for Your Practice

In recognition of National Diabetes Education Week, Endocrinology Advisor compiled a list of resources to assist clinicians when educating patients with diabetes about their condition.

Prevalence of Gestational Diabetes Increased From 2012 to 2016

Prevalence of Gestational Diabetes Increased From 2012 to 2016

The prevalence of gestational diabetes was 6.0 percent in 2016, with a slight increase seen from 2012 to 2016.

Intensive BP, Lipid Control in T2D May Increase Risk for Adverse Kidney Events

Intensive BP, Lipid Control in T2D May Increase Risk for Adverse Kidney Events

Intensive BP control and fenofibrate use in patients with T2D who are at high risk for CVD may increase the risk for adverse kidney events.

Increasing Incidence of Diabetes After Immune Checkpoint Inhibitor Therapy

Increasing Incidence of Diabetes After Immune Checkpoint Inhibitor Therapy

There is increased reporting of rapidly progressive diabetes associated with immune checkpoint inhibitor therapy.

Another Antihypertensive Recalled Due to Potentially Carcinogenic Impurity

Another Antihypertensive Recalled Due to Potentially Carcinogenic Impurity

The impurity was identified following laboratory testing conducted by the Food and Drug Administration (FDA); this is the first non-valsartan product that the Agency has found to contain NDEA.

Exposure to Ready-to-Eat Food Outlets Associated With Risk for Type 2 Diabetes

Exposure to Ready-to-Eat Food Outlets Associated With Risk for Type 2 Diabetes

Access to ready-to-eat outlets that sell food for instant consumption is associated with greater risk for type 2 diabetes.

Triponderal Mass Index Not Superior to BMI in Estimating Obesity Outcomes

Triponderal Mass Index Not Superior to BMI in Estimating Obesity Outcomes

Triponderal mass index alone and in combination with body mass index (BMI) or subscapular skinfold thickness was not superior to BMI alone for estimating obesity-related outcomes in adulthood.

Bardoxolone Methyl Leads to Weight Loss in T2D with Concurrent Chronic Kidney Disease

Bardoxolone Methyl Leads to Weight Loss in T2D with Concurrent Chronic Kidney Disease

Treatment with bardoxolone methyl resulted in significant weight loss and showed no evidence of muscle wasting in patients with type 2 diabetes and stage IV chronic kidney disease.

Canagliflozin Approved to Reduce Risk for Cardiovascular Events in T2D

Canagliflozin Approved to Reduce Risk for Cardiovascular Events in T2D

The effect of Invokana on CV risk was evaluated in the CANVAS (CANagliflozin cardioVascular Assessment Study) Program in >10,000 adults with T2D who had established CV disease or were at risk for CV disease with ≥2 risk factors.

Hyperglycemia, Obesity, Hypertriglyceridemia Negatively Related to CAN in T2D

Hyperglycemia, Obesity, Hypertriglyceridemia Negatively Related to CAN in T2D

Hyperglycemia, obesity, and hypertriglyceridemia in type 2 diabetes are negatively related to indices of cardiovascular autonomic neuropathy.

Weight Regain After Bariatric Surgery to Predict Clinical Outcomes

Weight Regain After Bariatric Surgery to Predict Clinical Outcomes

Measures that quantified weight regain as a percentage of maximum weight lost had the strongest association and best fit with clinical outcomes.

Early Natural Menopause Linked to Life Expectancy, Years With T2D

Early Natural Menopause Linked to Life Expectancy, Years With T2D

Compared with women who experience normal or late menopause, women who experience early natural menopause have a shorter life expectancy and spend fewer years without type 2 diabetes.

Dual GIP, GLP-1 Receptor Agonist Effective for Weight Loss, Glucose Control in T2D

Dual GIP, GLP-1 Receptor Agonist Effective for Weight Loss, Glucose Control in T2D

LY3298176, a dual GIP and GLP-1 receptor agonist, showed significantly better efficacy than dulaglutide with regard to glucose control and weight loss in type 2 diabetes.

Type 2 Diabetes an Independent Risk Factor for Coronary Artery Disease

Type 2 Diabetes an Independent Risk Factor for Coronary Artery Disease

Type 2 diabetes is an independent risk factor for sudden cardiac arrest and death in patients with coronary artery disease with preserved ejection fraction.

Biomarkers of Dairy Fat Consumption Inversely Associated With Type 2 Diabetes Risk

Biomarkers of Dairy Fat Consumption Inversely Associated With Type 2 Diabetes Risk

Researchers found that higher levels of fatty acid biomarkers 15:0, 17:0, and trans-16:1n7 were inversely associated with risk for T2D.

AHA, ADA, and Others Concerned Over Latest Trump Administration ACA Guidance

AHA, ADA, and Others Concerned Over Latest Trump Administration ACA Guidance

More than 25 professional medical and patient advocacy organizations are in opposition to the Trump Administration's latest effort to undermine the Affordable Care Act.

Gastric Banding vs Metformin for Improved Insulin Sensitivity in Mild T2D

Gastric Banding vs Metformin for Improved Insulin Sensitivity in Mild T2D

Gastric banding and metformin resulted in similar improvements in insulin sensitivity in moderately obese adults with impaired glucose tolerance or mild T2D over a 2-year period.

Dose-Dependent Relationship Between Smoking and Cardiovascular Complications in T1D

Dose-Dependent Relationship Between Smoking and Cardiovascular Complications in T1D

There is a dose-dependent association between smoking and coronary heart disease in patients with type 1 diabetes.

Ready-to-Use Glucagon Rescue Pen for Severe Hypoglycemia Under FDA Review

Ready-to-Use Glucagon Rescue Pen for Severe Hypoglycemia Under FDA Review

The NDA included findings from multiple Phase 3 trials evaluating the safety, efficacy, and utility of the Xeris glucagon rescue pen auto-injector to treat severe hypoglycemia vs currently available glucagon emergency kits in children, adolescents, and adults with type 1 diabetes.

Inadequate Reimbursement May Inhibit Diabetes Prevention Program

Inadequate Reimbursement May Inhibit Diabetes Prevention Program

The costs of delivering a new Medicare Diabetes Prevention Program (MDPP) may be higher than the expected reimbursement.

Incretin-Based Therapies Not Associated With New-Onset Depression, Self-Harm in T2D

Incretin-Based Therapies Not Associated With New-Onset Depression, Self-Harm in T2D

There was not a clinically relevant association between DPP-4 inhibitors or GLP-1 receptor agonists and depression or self-harm in type 2 diabetes.

Glucose Dysregulation Begins Years Before Diabetes Diagnosis

Glucose Dysregulation Begins Years Before Diabetes Diagnosis

Individuals who develop diabetes or prediabetes have elevated fasting plasma glucose (FPG) at least 10 years before diagnosis.

Bacillus Calmette-Guerin Vaccination Lowers HbA1c in Type 1 Diabetes

Bacillus Calmette-Guerin Vaccination Lowers HbA1c in Type 1 Diabetes

Bacillus Calmette-Guerin vaccination impacted blood sugar levels in T1D by causing a systemic shift in glucose metabolism from oxidative phosphorylation to aerobic glycolysis.

Severity of Metabolic Syndrome Indicates Risk for T2D, CVD in Prediabetes Treatment

Severity of Metabolic Syndrome Indicates Risk for T2D, CVD in Prediabetes Treatment

Researchers analyzed how improvements in metabolic syndrome may impact the risk of developing type 2 diabetes and cardiovascular disease in patients with prediabetes.

Patients With Diabetes Have Higher Risk for Death From Alcohol, Accidents, Suicide

Patients With Diabetes Have Higher Risk for Death From Alcohol, Accidents, Suicide

Patients with diabetes have increased mortality due to suicide, alcohol-related causes, and accidents than those without diabetes.

Deep Learning Algorithm Efficiently Detects Vision-Threatening Diabetic Retinopathy

Deep Learning Algorithm Efficiently Detects Vision-Threatening Diabetic Retinopathy

The artificial intelligence-based deep learning algorithm shows robust performance in the detection of vision-threatening referable diabetic retinopathy.

Bone-Derived Factors in the Treatment of Diabetes

Bone-Derived Factors in the Treatment of Diabetes

A growing body of research highlights the important role of bone in glucose metabolism.

Bariatric Surgery Reduces Macrovascular Complications in Obesity, T2D

Bariatric Surgery Reduces Macrovascular Complications in Obesity, T2D

For patients with severe obesity and type 2 diabetes, bariatric surgery is associated with a lower risk for macrovascular outcomes compared with not undergoing surgery.

Periodic Fasting May Reduce Medication Use in T2D

Periodic Fasting May Reduce Medication Use in T2D

Medically supervised, therapeutic fasting regimens can help reverse type 2 diabetes (T2D) and minimize the need for pharmacological interventions.

Cost a key consideration of WHO guidelines for diabetes treatment intensification

WHO guidelines recommend selecting sulfonylureas as the single best second-line agent for Type 2 Diabetes Mellitus (T2DM) patients.

Maternal Gluten Intake Associated With Risk for Type 1 Diabetes in Offspring

Maternal Gluten Intake Associated With Risk for Type 1 Diabetes in Offspring

There was an association between high maternal intake of gluten and an elevated risk for type 1 diabetes for the child.

Patterns of Evidence-Based Diabetes Interventions at Local Health Departments

Patterns of Evidence-Based Diabetes Interventions at Local Health Departments

Improving evidence-based decision making capacity within local health departments can lead to increased offering of evidence-based interventions for diabetes management.

Fasting Glycemic Variability Indicates Increased Risk for Type 2 Diabetes

Fasting Glycemic Variability Indicates Increased Risk for Type 2 Diabetes

Greater variation of fasting plasma glucose over time is associated with an increased risk of developing type 2 diabetes.

Domestic Refrigeration May Pose Underestimated Risk for Insulin Quality

Domestic Refrigeration May Pose Underestimated Risk for Insulin Quality

In many cases, insulin was exposed to temperatures outside the recommended range, especially when refrigerated.

Sitagliptin Provides Better Glycemic Control Than Dapagliflozin in T2D With Renal Impairment

Sitagliptin Provides Better Glycemic Control Than Dapagliflozin in T2D With Renal Impairment

Study results indicated that sitagliptin showed greater glycemic efficacy than dapagliflozin treatment.

Diabetes Associated With Elevated Risk for Arthritis, Osteoporosis

Diabetes Associated With Elevated Risk for Arthritis, Osteoporosis

Osteoarthritis was the most common form of arthritis in patients with diabetes but rheumatoid arthritis had the most pronounced association with diabetes.

Cardiovascular Outcomes for Albiglutide Treatment in T2D

Cardiovascular Outcomes for Albiglutide Treatment in T2D

For patients with type 2 diabetes and existing cardiovascular disease, albiglutide results in fewer cardiovascular events.

Empagliflozin Treatment Positively Impacts Life Expectancy in T2D With CVD

Empagliflozin Treatment Positively Impacts Life Expectancy in T2D With CVD

For this analysis, the authors used follow-up data from all 7020 patients included in the EMPA-REG OUTCOME trial to estimate the effect of empagliflozin on all-cause mortality vs placebo over the duration of a patient's lifetime.

Risk for Type 2 Diabetes, Cardiovascular Disease Elevated in Patients With Psoriatic Arthritis

Risk for Type 2 Diabetes, Cardiovascular Disease Elevated in Patients With Psoriatic Arthritis

Risk for type 2 diabetes, ischemic heart disease, and peripheral vascular disease was elevated among patients with psoriatic arthritis compared with the general population.

Exercise After Overnight Fasting Stabilizes Glucose Levels in Type 1 Diabetes

Exercise After Overnight Fasting Stabilizes Glucose Levels in Type 1 Diabetes

The effect of high-intensity interval training with a bout of moderate-intensity continuous training on glucose levels was examined in T1D.

Lorcaserin Reduces Risk for Incident Diabetes in Patients With Prediabetes

Lorcaserin Reduces Risk for Incident Diabetes in Patients With Prediabetes

In this new analysis, researchers looked at the long-term effects of the drug on diabetes prevention and remission in these patients.

Updated ADA, EASD Consensus Guidelines for Managing Hyperglycemia in T2D

Updated ADA, EASD Consensus Guidelines for Managing Hyperglycemia in T2D

Recommendations in the report highlight the importance of patient-centered decision making for glycemic management and improving diet and exercise for patients with T2D.

Positive Results for Empagliflozin in Type 1 Diabetes Trials

Positive Results for Empagliflozin in Type 1 Diabetes Trials

The EASE Phase 3 program included 2 double-blind, placebo-controlled trials investigating the efficacy and safety of empagliflozin as an adjunct to insulin therapy in adults with type 1 diabetes.

FDA Issues Safety Communication Regarding Pen Needle Use

FDA Issues Safety Communication Regarding Pen Needle Use

Standard pen needles have an outer cover and removable inner needle cover, while safety pen needles have an outer cover and a fixed inner needle shield that is not removed before an injection.

Safety and Mortality Outcomes Following Pediatric Growth Hormone Therapy

Safety and Mortality Outcomes Following Pediatric Growth Hormone Therapy

Primary cancer rates and mortality risk were no higher for pediatric patients treated with growth hormone therapy.

Obesity Reduces Number of Disease-Free Years Regardless of Lifestyle

Obesity Reduces Number of Disease-Free Years Regardless of Lifestyle

Obesity is associated with loss of disease-free years irrespective of position in the social hierarchy and lifestyle.

Better Glycemic Control With Closed-Loop Insulin Delivery

Better Glycemic Control With Closed-Loop Insulin Delivery

For patients with suboptimally controlled type 1 diabetes, day-and-night hybrid closed-loop insulin delivery improves glucose control compared with sensor-augmented pump therapy.

Elevated HbA1c After Onset of T1D Predicts Psychiatric Comorbidity

Elevated HbA1c After Onset of T1D Predicts Psychiatric Comorbidity

High average glycated hemoglobin levels during the first two years after type 1 diabetes onset predict higher risk for psychiatric diagnoses.

Basal Insulin Combination Therapies With Vildagliptin or Lixisenatide Equally Effective for T2D

Basal Insulin Combination Therapies With Vildagliptin or Lixisenatide Equally Effective for T2D

Combination therapies of basal insulin with either vildagliptin or lixisenatide are similarly effective at producing glycemic control improvements.

Genetics May Identify Type 2 Diabetes Subtypes

Genetics May Identify Type 2 Diabetes Subtypes

Clusters of type 2 diabetes loci and traits have been identified.

Effects of Fixed-Ratio Pramlintide and Insulin on Postprandial Hyperglycemia in T1D

Effects of Fixed-Ratio Pramlintide and Insulin on Postprandial Hyperglycemia in T1D

Coadministration of 24 hours of fixed-ratio pramlintide and regular human insulin improves postprandial hyperglycemia and glycemic variability in patients with type 1 diabetes.

Sleep Disturbances Affect Glycemic Control in Patients With Type 2 Diabetes

Sleep Disturbances Affect Glycemic Control in Patients With Type 2 Diabetes

Findings from the study showed a graded association between shorter average sleep duration and higher HbA1c concentrations among participants with diabetes.

Many Countries Failing to Reduce Deaths From Noncommunicable Diseases

Many Countries Failing to Reduce Deaths From Noncommunicable Diseases

Many countries are falling short on targets to reduce mortality from non-communicable diseases.

SGLT2 Inhibitors Associated With Increased Risk for Genital Infections

SGLT2 Inhibitors Associated With Increased Risk for Genital Infections

SGLT2 inhibitors were associated with an approximately 3-fold higher risk for developing genital infections.

Replacing Red Meat With Poultry or Fish Lowers Type 2 Diabetes Risk

Replacing Red Meat With Poultry or Fish Lowers Type 2 Diabetes Risk

Substituting processed red meat with poultry or fish and replacing total red meat with fish were associated with a lowered risk for type 2 diabetes.

Prevalence of Diabetes in US Adults for 2013 to 2016

Prevalence of Diabetes in US Adults for 2013 to 2016

The prevalence of diabetes was 14.0 percent among U.S. adults in 2013 to 2016, with prevalence of undiagnosed diabetes 4.3 percent.

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