Diabetes Complications

High-Deductible Insurance Linked to Delayed Care for Diabetes Complications

High-Deductible Insurance Linked to Delayed Care for Diabetes Complications

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Mandated enrollment in a high-deductible insurance plan among persons with diabetes was associated with delays in seeking care for diabetes complications.

Coronary Bypass Grafting Superior to Percutaneous Coronary Intervention With Drug-Eluting Stents for Reducing Mortality in Diabetes

Coronary Bypass Grafting Superior to Percutaneous Coronary Intervention With Drug-Eluting Stents for Reducing Mortality in Diabetes

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Coronary artery bypass grafting may be a superior revascularization strategy in patients with diabetes and multivessel disease.

Type 1 Diabetes Confers Extra Risk for Autoimmune Diseases

Type 1 Diabetes Confers Extra Risk for Autoimmune Diseases

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Type 1 diabetes predisposes children and adults to autoimmune diseases, which can impair glucose metabolism and interfere with insulin therapy.

Noninferior CV Outcomes for Linagliptin in T2D With High CV, Renal Risk

Noninferior CV Outcomes for Linagliptin in T2D With High CV, Renal Risk

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Linagliptin added to usual care compared with placebo added to usual care resulted in a noninferior risk for a composite cardiovascular or renal outcome over a median 2.2 years.

Dapagliflozin Lowers Heart Failure Hospitalization Rates in High-Risk Patients With Diabetes

Dapagliflozin Lowers Heart Failure Hospitalization Rates in High-Risk Patients With Diabetes

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Dapagliflozin was not associated with either a higher or lower rate of MACE compared with placebo in patients with type 2 diabetes who had or were at risk for atherosclerotic cardiovascular disease.

Measuring Time in Range During CGM May Be Useful Outcome Metric for Clinical Trials

Measuring Time in Range During CGM May Be Useful Outcome Metric for Clinical Trials

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TIR is strongly associated with the risk of microvascular complications and should be an acceptable end point for clinical trials.

Patients With T2D and Sickle-Cell Trait at Higher Risk for Complications

Patients With T2D and Sickle-Cell Trait at Higher Risk for Complications

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Diabetic complications were more prevalent in patients with both sickle-cell trait and T2D than in patients with T2D alone.

Diabetes Education Week 2018: Patient Resources for Your Practice

Diabetes Education Week 2018: Patient Resources for Your Practice

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In recognition of National Diabetes Education Week, Endocrinology Advisor compiled a list of resources to assist clinicians when educating patients with diabetes about their condition.

Bardoxolone Methyl Leads to Weight Loss in T2D with Concurrent Chronic Kidney Disease

Bardoxolone Methyl Leads to Weight Loss in T2D with Concurrent Chronic Kidney Disease

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Treatment with bardoxolone methyl resulted in significant weight loss and showed no evidence of muscle wasting in patients with type 2 diabetes and stage IV chronic kidney disease.

Dose-Dependent Relationship Between Smoking and Cardiovascular Complications in T1D

Dose-Dependent Relationship Between Smoking and Cardiovascular Complications in T1D

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There is a dose-dependent association between smoking and coronary heart disease in patients with type 1 diabetes.

Severity of Metabolic Syndrome Indicates Risk for T2D, CVD in Prediabetes Treatment

Severity of Metabolic Syndrome Indicates Risk for T2D, CVD in Prediabetes Treatment

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Researchers analyzed how improvements in metabolic syndrome may impact the risk of developing type 2 diabetes and cardiovascular disease in patients with prediabetes.

Deep Learning Algorithm Efficiently Detects Vision-Threatening Diabetic Retinopathy

Deep Learning Algorithm Efficiently Detects Vision-Threatening Diabetic Retinopathy

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The artificial intelligence-based deep learning algorithm shows robust performance in the detection of vision-threatening referable diabetic retinopathy.

Diabetes Associated With Elevated Risk for Arthritis, Osteoporosis

Diabetes Associated With Elevated Risk for Arthritis, Osteoporosis

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Osteoarthritis was the most common form of arthritis in patients with diabetes but rheumatoid arthritis had the most pronounced association with diabetes.

Empagliflozin Treatment Positively Impacts Life Expectancy in T2D With CVD

Empagliflozin Treatment Positively Impacts Life Expectancy in T2D With CVD

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For this analysis, the authors used follow-up data from all 7020 patients included in the EMPA-REG OUTCOME trial to estimate the effect of empagliflozin on all-cause mortality vs placebo over the duration of a patient's lifetime.

Elevated HbA1c After Onset of T1D Predicts Psychiatric Comorbidity

Elevated HbA1c After Onset of T1D Predicts Psychiatric Comorbidity

High average glycated hemoglobin levels during the first two years after type 1 diabetes onset predict higher risk for psychiatric diagnoses.

SGLT2 Inhibitors Associated With Increased Risk for Genital Infections

SGLT2 Inhibitors Associated With Increased Risk for Genital Infections

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SGLT2 inhibitors were associated with an approximately 3-fold higher risk for developing genital infections.

Bullous Pemphigoid Risk in Patients With Diabetes Treated With DPP-4 Inhibitors

Bullous Pemphigoid Risk in Patients With Diabetes Treated With DPP-4 Inhibitors

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The association between DPP-4 inhibitor use and the risk for developing bullous pemphigoid was examined.

Association Between Urine Complement Proteins and Kidney Disease, Mortality in T2D

Association Between Urine Complement Proteins and Kidney Disease, Mortality in T2D

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Researchers suggest complement pathway activation plays a role in diabetic kidney disease progression in people with proteinuria.

Intensive Blood Pressure Therapy Lowers Cardiovascular Risk in Diabetes

Intensive Blood Pressure Therapy Lowers Cardiovascular Risk in Diabetes

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Intensive blood pressure therapy is associated with a significantly lower risk for serious cardiovascular events in the adults with diabetes.

FDA to Review Eylea for the Treatment of Non-Proliferative Diabetic Retinopathy

FDA to Review Eylea for the Treatment of Non-Proliferative Diabetic Retinopathy

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The sBLA includes results from the Phase 3 PANORAMA trial, which enrolled 402 patients with NPDR.

Diabetic Retinopathy Risk Not Increased With GLP-1 Receptor Agonist Use in T2D

Diabetic Retinopathy Risk Not Increased With GLP-1 Receptor Agonist Use in T2D

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Investigators examined whether the use of glucagon-like peptide-1 receptor agonists is associated with an increased risk for incident diabetic retinopathy.

Treating Painful Diabetic Peripheral Neuropathy With Electroacupuncture

Treating Painful Diabetic Peripheral Neuropathy With Electroacupuncture

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Investigators sought to determine the safety and efficacy of electroacupuncture for painful diabetic peripheral neuropathy.

Popliteal Sciatic Nerve Block May Increase Time to First Opioid Request in Diabetic Peripheral Neuropathy

Popliteal Sciatic Nerve Block May Increase Time to First Opioid Request in Diabetic Peripheral Neuropathy

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Patients with type 2 diabetes and diabetic peripheral neuropathy may have an increased time to first opioid request and reduced time to onset of sensory blockade after an ultrasound-guided popliteal sciatic nerve block compared with patients without neuropathy.

ISPAD Issues Consensus Statement on Diabetic Ketoacidosis and Hyperglycemia

ISPAD Issues Consensus Statement on Diabetic Ketoacidosis and Hyperglycemia

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ISPAD recommends adjustments for fluid management regarding rehydration rates in children and adolescents with diabetes ketoacidosis.

Sustained-Release Sodium Nitrite for Diabetic Neuropathic Pain Not Associated With Headaches

Sustained-Release Sodium Nitrite for Diabetic Neuropathic Pain Not Associated With Headaches

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A sustained-release formulation of sodium nitrite may not be associated with headaches and dizziness reported by patients treated with the immediate-release formulation of sodium nitrite for diabetic peripheral neuropathy.

High Risk of Death After Major Diabetes-Related Amputations

High Risk of Death After Major Diabetes-Related Amputations

There is a high risk of postoperative mortality among patients undergoing lower-limb amputation.

Repeated Ranibizumab Injections Does Not Impair Macular Perfusion

Repeated Ranibizumab Injections Does Not Impair Macular Perfusion

For patients with diabetic macular edema, repeated ranibizumab treatment does not appear to be associated with impaired macular perfusion.

FDA Approves First Shock Wave Device for Treating Diabetic Foot Ulcers

FDA Approves First Shock Wave Device for Treating Diabetic Foot Ulcers

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The FDA has granted marketing clearance of the first shock wave device intended for use in the treatment of chronic, full-thickness diabetic foot ulcers.

Spinal Cord Stimulation Reduces Pain in Diabetic Polyneuropathy

Spinal Cord Stimulation Reduces Pain in Diabetic Polyneuropathy

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As many as one-quarter of individuals with diabetes will experience painful neuropathic symptoms for which treatment is limited.

Patients With Diabetic Retinopathy Experience Barriers to Diabetes Self-Management

Patients With Diabetic Retinopathy Experience Barriers to Diabetes Self-Management

Among Asians, individuals with mild and moderate diabetic retinopathy are more likely to have fallen, and greater perceived barriers to diabetes self-management are associated with the severity of DR in an Asian population.

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