Cushings Syndrome

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Nonfunctioning Adrenal Incidentaloma Associated With Metabolic Syndrome

Nonfunctioning Adrenal Incidentaloma Associated With Metabolic Syndrome

Investigators sought to determine the frequency of metabolic syndrome in patients with nonfunctioning adrenal incidentalomas.

Positive Results for Recorlev in Phase 3 Cushing Syndrome Trial

Positive Results for Recorlev in Phase 3 Cushing Syndrome Trial

Results from this single-arm, open-label study found that 30% of patients achieved normalization of mean urinary free cortisol (UFC) after 6 months of maintenance treatment with levoketoconazole, without a dose increase (P<.25).

Azedra Approved to Treat Rare Tumors of the Adrenal Gland

Azedra Approved to Treat Rare Tumors of the Adrenal Gland

Azedra should be used by or under the control of physicians who are qualified by specific training and experience in the safe use and handling of radiopharmaceuticals.

Glucocorticoid Replacement Improves Circadian Rhythm in Adrenal Insufficiency

Glucocorticoid Replacement Improves Circadian Rhythm in Adrenal Insufficiency

Administering glucocorticoid leads to entrainment of molecular clocks in human peripheral blood mononuclear cells by regulating BMAL-1 and PER2-3.

Age-Related Differences in Manifestation of Cushing Disease Identified

Age-Related Differences in Manifestation of Cushing Disease Identified

Researchers assessed disease presentation and clinical outcomes in an older population of individuals with Cushing disease.

Cardiovascular Function May Improve After Cure of Cushing Syndrome

Cardiovascular Function May Improve After Cure of Cushing Syndrome

Study assessed cardiovascular function, quality of life, and mental/physical health in overt and cured Cushing syndrome.

Pain Perception in Adrenal Insufficiency Not Affected by Hydrocortisone Dose

Pain Perception in Adrenal Insufficiency Not Affected by Hydrocortisone Dose

Mechanical pain perception and somatosensory function in secondary adrenal insufficiency were examined.

New Research Highlights Possible Genetic Cause of Cushing's Disease

New Research Highlights Possible Genetic Cause of Cushing's Disease

The analysis led to the identification of 4 potentially pathogenic missense variants in CABLES1.

Functional Hypothalamic Amenorrhea Diagnosis and Treatment Guidelines Released

Functional Hypothalamic Amenorrhea Diagnosis and Treatment Guidelines Released

Functional hypothalamic amenorrhea should be diagnosed by exclusion.

Pediatric Endocrine Society Provides Guidance for Growth Hormone Use in Pediatric Patients

Pediatric Endocrine Society Provides Guidance for Growth Hormone Use in Pediatric Patients

The guidelines focused on idiopathic short stature, growth hormone deficiency, and primary IGF-I deficiency.

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