Cardiovascular And Metabolic Disorders

Metabolic Health Predicative of Cognitive Development in Children

Metabolic Health Predicative of Cognitive Development in Children

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Researchers assessed whether current metabolic parameters are inversely associated with cognitive functioning.

Emotional Hyper-Reactivity and Cardiometabolic Risk in Remitted Bipolar Disorder

Emotional Hyper-Reactivity and Cardiometabolic Risk in Remitted Bipolar Disorder

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Patients with remitted bipolar disorder and emotional hyper-reactivity also have significantly higher levels of low-grade inflammation, hypertension, and impaired glucose metabolism, indicating a higher risk for cardiometabolic dysfunction.

 USPSTF Does Not Recommend Electrocardiography Screening in Low-Risk CVD

USPSTF Does Not Recommend Electrocardiography Screening in Low-Risk CVD

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The United States Preventive Services Task Force does not recommend screening with resting or exercise electrocardiography in asymptomatic individuals at low risk for cardiovascular disease events.

Osteoporosis Drug Shows Cardioprotective Potential at 10-Year Follow-Up

Osteoporosis Drug Shows Cardioprotective Potential at 10-Year Follow-Up

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The 1-year cardiovascular mortality hazard ratio (HR) for alendronate users was 0.33 (95% CI, 0.17 to 0.65) and 0.55 for incident myocardial infarction (95% CI, 0.34 to 0.89).

Eplerenone May Improve Cardiovascular Disease Risk in HIV

Eplerenone May Improve Cardiovascular Disease Risk in HIV

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Researchers investigated effects of eplerenone on insulin sensitivity, inflammatory indices, and other metabolic parameters in HIV.

Antipsychotics Increase Risk for Metabolic Syndrome, CVD in Younger Patients

Antipsychotics Increase Risk for Metabolic Syndrome, CVD in Younger Patients

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Younger patients treated with antipsychotics after experiencing a first episode of psychosis are at an increased risk for metabolic syndrome and cardiovascular disease.

Aortic Stiffness, Concentric LV Remodeling Linked in Type 2 Diabetes

Aortic Stiffness, Concentric LV Remodeling Linked in Type 2 Diabetes

Researchers used multiparametric cardiovascular magnetic resonance imaging to examine the correlation between aortic stiffness and LV geometry in younger adults with type 2 diabetes.

Metabolic Syndrome and Skin Disorders: Association Is More Than Skin Deep

Metabolic Syndrome and Skin Disorders: Association Is More Than Skin Deep

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Knowing that certain characteristics increase the risk for dermatology patients who may have metabolic syndrome will enable clinicians to identify patients who may have specific cardiovascular risks.

In LVSD, Diabetes Tied to Higher Risk of Heart Failure

In LVSD, Diabetes Tied to Higher Risk of Heart Failure

In patients with asymptomatic left ventricular systolic dysfunction, diabetes is associated with an increased risk of developing heart failure.

Metabolic Syndrome Frequency Assessed in Systemic Lupus Erythematosus

Metabolic Syndrome Frequency Assessed in Systemic Lupus Erythematosus

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The frequency of metabolic syndrome among patients with SLE was approximately 45%.

Rheumatoid Arthritis Not as Likely to Increase CVD Risk as Diabetes

Rheumatoid Arthritis Not as Likely to Increase CVD Risk as Diabetes

Using both public and private health insurance claims data, investigators conducted a retrospective cohort study to assess cardiovascular risk in the setting of diabetes and rheumatoid arthritis.

Young Adults With Type 1 Diabetes Show Muscle Metabolic Deficiencies

Young Adults With Type 1 Diabetes Show Muscle Metabolic Deficiencies

Physically active young adults with type 1 diabetes have alterations in mitochondrial ultrastructure and bioenergetics within skeletal muscle.

Metabolic Syndrome Associated With Higher ALT Levels in Chronic Hepatitis B

Metabolic Syndrome Associated With Higher ALT Levels in Chronic Hepatitis B

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Findings highlight the importance of screening for metabolic syndrome (MS) and the potential for MS to influence alanine aminotransferase and its interpretation in the context of HBV treatment decisions.

Sacubitril/Valsartan May Help Preserve Kidney Function in Patients With HFrEF

Sacubitril/Valsartan May Help Preserve Kidney Function in Patients With HFrEF

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Compared with the enalapril-treated group, those treated with sacubitril/valsartan were found to have significantly slower kidney decline.

Soluble Klotho Levels Predictive of Kidney Failure in Type 2 Diabetes

Soluble Klotho Levels Predictive of Kidney Failure in Type 2 Diabetes

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In patients with type 2 diabetes and with relatively preserved estimated glomerular filtration rate, reduced levels of soluble Klotho predict renal function decline independent of traditional risk markers.

FT3 Level Associated With the Development of Metabolic Syndrome

FT3 Level Associated With the Development of Metabolic Syndrome

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Researchers designed a cohort study to examine whether serum thyroid hormone levels within the reference range are predictive factors for developing metabolic syndrome in adults.

Canagliflozin May Improve Renal Outcomes in Patients With Type 2 Diabetes

Canagliflozin May Improve Renal Outcomes in Patients With Type 2 Diabetes

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The renal protective benefit was seen in patients with both reduced (eGFR <60mL/min/1.73m2) and preserved (eGFR ≥60mL/min/1.73m2) renal function.

Menopause Symptom Severity May Predict Heart Disease

Menopause Symptom Severity May Predict Heart Disease

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Researchers examined whether menopausal symptoms, quality of life, and depression are related to arterial stiffness, a risk factor for cardiovascular disease.

Eating Pecans May Cut Risk for Cardiovascular Disease, Diabetes

Eating Pecans May Cut Risk for Cardiovascular Disease, Diabetes

Changes in serum insulin and homeostatic model assessment of insulin resistance and beta cell function were significantly greater compared to the control diet

Noninvasive CAD Screening May Reduce Cardiac Events in Individuals With Asymptomatic Diabetes

Noninvasive CAD Screening May Reduce Cardiac Events in Individuals With Asymptomatic Diabetes

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Compared with standard care, noninvasive coronary artery disease screening reduced cardiac events by 27% in individuals with asymptomatic diabetes. Results justify larger, appropriately powered trials to potentially revisit current recommendations.

Risk for Cardiovascular Disease Higher in Survivors of Testicular Cancer

Risk for Cardiovascular Disease Higher in Survivors of Testicular Cancer

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Results from the ongoing Platinum Study revealed the prevalence of risk factors for CVD among survivors of testicular cancer who received chemotherapy for their cancer.

Only Half of Adults With Familial Hypercholesterolemia on Statins

Only Half of Adults With Familial Hypercholesterolemia on Statins

Only about 50% of adults with familial hypercholesterolemia are on statin therapy, and approximately 30% of those are taking high-intensity statins.

Change in BMI During Puberty Tied to Later Heart Failure Risk in Men

Change in BMI During Puberty Tied to Later Heart Failure Risk in Men

Change in body mass index to overweight during puberty significantly increases men's risk of heart failure later in life.

Negative Symptoms Increase Cardiovascular Risk in Schizophrenia

Negative Symptoms Increase Cardiovascular Risk in Schizophrenia

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Although various clinical and psychosocial factors were associated with unhealthy lifestyle factors and higher risk for CVD, the strongest associations were with negative symptoms.

Cardiovascular Outcomes of SGLT-2i vs Other Glucose-Lowering Drugs in T2D

Cardiovascular Outcomes of SGLT-2i vs Other Glucose-Lowering Drugs in T2D

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A recent study evaluated the effects of SGLT-2i and other glucose-lowering drugs on cardiovascular event outcomes in patients with type 2 diabetes from 6 countries in 3 world regions.

Canakinumab Does Not Appear to Prevent Diabetes Onset

Canakinumab Does Not Appear to Prevent Diabetes Onset

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The new analysis focuses on the remaining 4960 patients, who had prediabetes at the start of the trial.

Effect of Menopausal Hormone Therapy on Cardiac Structure, Function

Effect of Menopausal Hormone Therapy on Cardiac Structure, Function

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Researchers examined the effect of menopausal hormone therapy on left ventricular and left atrial chamber structure and function changes, which are markers of subclinical cardiovascular disease.

Tresiba Label Updated With Data on Severe Hypoglycemia, CV Outcomes

Tresiba Label Updated With Data on Severe Hypoglycemia, CV Outcomes

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The Tresiba label was updated to reflect safety outcomes from the DEVOTE trial.

Metformin Use Linked to Reduced Risk of Statin-Associated Muscle Pain

Metformin Use Linked to Reduced Risk of Statin-Associated Muscle Pain

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Statin-associated muscle pain can hinder medication adherence which could potentially lead to an increased risk of cardiovascular events.

Effect of High Androgen Levels on Cardiovascular Risk in Postmenopausal Women

Effect of High Androgen Levels on Cardiovascular Risk in Postmenopausal Women

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Researchers conducted a prospective, population-based cohort study to assess the risk for cardiovascular disease in postmenopausal women with increased androgen levels.

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