Cardiovascular And Metabolic Disorders

Rheumatoid Arthritis Not as Likely to Increase CVD Risk as Diabetes

Rheumatoid Arthritis Not as Likely to Increase CVD Risk as Diabetes

Using both public and private health insurance claims data, investigators conducted a retrospective cohort study to assess cardiovascular risk in the setting of diabetes and rheumatoid arthritis.

Young Adults With Type 1 Diabetes Show Muscle Metabolic Deficiencies

Young Adults With Type 1 Diabetes Show Muscle Metabolic Deficiencies

Physically active young adults with type 1 diabetes have alterations in mitochondrial ultrastructure and bioenergetics within skeletal muscle.

Sacubitril/Valsartan May Help Preserve Kidney Function in Patients With HFrEF

Sacubitril/Valsartan May Help Preserve Kidney Function in Patients With HFrEF

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Compared with the enalapril-treated group, those treated with sacubitril/valsartan were found to have significantly slower kidney decline.

Soluble Klotho Levels Predictive of Kidney Failure in Type 2 Diabetes

Soluble Klotho Levels Predictive of Kidney Failure in Type 2 Diabetes

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In patients with type 2 diabetes and with relatively preserved estimated glomerular filtration rate, reduced levels of soluble Klotho predict renal function decline independent of traditional risk markers.

FT3 Level Associated With the Development of Metabolic Syndrome

FT3 Level Associated With the Development of Metabolic Syndrome

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Researchers designed a cohort study to examine whether serum thyroid hormone levels within the reference range are predictive factors for developing metabolic syndrome in adults.

Canagliflozin May Improve Renal Outcomes in Patients With Type 2 Diabetes

Canagliflozin May Improve Renal Outcomes in Patients With Type 2 Diabetes

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The renal protective benefit was seen in patients with both reduced (eGFR <60mL/min/1.73m2) and preserved (eGFR ≥60mL/min/1.73m2) renal function.

Menopause Symptom Severity May Predict Heart Disease

Menopause Symptom Severity May Predict Heart Disease

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Researchers examined whether menopausal symptoms, quality of life, and depression are related to arterial stiffness, a risk factor for cardiovascular disease.

Eating Pecans May Cut Risk for Cardiovascular Disease, Diabetes

Eating Pecans May Cut Risk for Cardiovascular Disease, Diabetes

Changes in serum insulin and homeostatic model assessment of insulin resistance and beta cell function were significantly greater compared to the control diet

Noninvasive CAD Screening May Reduce Cardiac Events in Individuals With Asymptomatic Diabetes

Noninvasive CAD Screening May Reduce Cardiac Events in Individuals With Asymptomatic Diabetes

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Compared with standard care, noninvasive coronary artery disease screening reduced cardiac events by 27% in individuals with asymptomatic diabetes. Results justify larger, appropriately powered trials to potentially revisit current recommendations.

Risk for Cardiovascular Disease Higher in Survivors of Testicular Cancer

Risk for Cardiovascular Disease Higher in Survivors of Testicular Cancer

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Results from the ongoing Platinum Study revealed the prevalence of risk factors for CVD among survivors of testicular cancer who received chemotherapy for their cancer.

Only Half of Adults With Familial Hypercholesterolemia on Statins

Only Half of Adults With Familial Hypercholesterolemia on Statins

Only about 50% of adults with familial hypercholesterolemia are on statin therapy, and approximately 30% of those are taking high-intensity statins.

Change in BMI During Puberty Tied to Later Heart Failure Risk in Men

Change in BMI During Puberty Tied to Later Heart Failure Risk in Men

Change in body mass index to overweight during puberty significantly increases men's risk of heart failure later in life.

Negative Symptoms Increase Cardiovascular Risk in Schizophrenia

Negative Symptoms Increase Cardiovascular Risk in Schizophrenia

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Although various clinical and psychosocial factors were associated with unhealthy lifestyle factors and higher risk for CVD, the strongest associations were with negative symptoms.

Cardiovascular Outcomes of SGLT-2i vs Other Glucose-Lowering Drugs in T2D

Cardiovascular Outcomes of SGLT-2i vs Other Glucose-Lowering Drugs in T2D

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A recent study evaluated the effects of SGLT-2i and other glucose-lowering drugs on cardiovascular event outcomes in patients with type 2 diabetes from 6 countries in 3 world regions.

Canakinumab Does Not Appear to Prevent Diabetes Onset

Canakinumab Does Not Appear to Prevent Diabetes Onset

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The new analysis focuses on the remaining 4960 patients, who had prediabetes at the start of the trial.

Effect of Menopausal Hormone Therapy on Cardiac Structure, Function

Effect of Menopausal Hormone Therapy on Cardiac Structure, Function

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Researchers examined the effect of menopausal hormone therapy on left ventricular and left atrial chamber structure and function changes, which are markers of subclinical cardiovascular disease.

Tresiba Label Updated With Data on Severe Hypoglycemia, CV Outcomes

Tresiba Label Updated With Data on Severe Hypoglycemia, CV Outcomes

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The Tresiba label was updated to reflect safety outcomes from the DEVOTE trial.

Metformin Use Linked to Reduced Risk of Statin-Associated Muscle Pain

Metformin Use Linked to Reduced Risk of Statin-Associated Muscle Pain

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Statin-associated muscle pain can hinder medication adherence which could potentially lead to an increased risk of cardiovascular events.

Effect of High Androgen Levels on Cardiovascular Risk in Postmenopausal Women

Effect of High Androgen Levels on Cardiovascular Risk in Postmenopausal Women

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Researchers conducted a prospective, population-based cohort study to assess the risk for cardiovascular disease in postmenopausal women with increased androgen levels.

Primary Prevention Outcomes With Aspirin in T2D and Heart Failure

Primary Prevention Outcomes With Aspirin in T2D and Heart Failure

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In patients with type 2 diabetes and heart failure, primary prevention with aspirin reduced all-cause mortality but increased nonfatal myocardial infarction and stroke.

Cardiovascular Function May Improve After Cure of Cushing Syndrome

Cardiovascular Function May Improve After Cure of Cushing Syndrome

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Study assessed cardiovascular function, quality of life, and mental/physical health in overt and cured Cushing syndrome.

No Cardiovascular Benefit With Fenofibrate in T2D and Hypertriglyceridemia

No Cardiovascular Benefit With Fenofibrate in T2D and Hypertriglyceridemia

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Statins were associated with a reduction in mortality but there was no significant difference in the composite end point with fenofibrates alone or in combination with statins.

Low Sperm Count Linked to Poor Metabolic, Cardiovascular, Bone Health

Low Sperm Count Linked to Poor Metabolic, Cardiovascular, Bone Health

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Researchers tested whether semen quality and reproductive function could be a marker of general health in men.

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