Cardiovascular And Metabolic Disorders

Characteristics of Acquired Partial Lipodystrophy With Metabolic Abnormalities

Characteristics of Acquired Partial Lipodystrophy With Metabolic Abnormalities

By

Investigators analyze characteristics of participants with acquired partial lipodystrophy who developed severe metabolic abnormalities.

High LDL in Young, Healthy Adults Leaves Them Vulnerable to CVD

High LDL in Young, Healthy Adults Leaves Them Vulnerable to CVD

Low-density lipoprotein cholesterol (LDL-C) and non-high density lipoprotein cholesterol (non-HDL-C) ≥160 mg/dL are independently associated with increased relative risk of cardiovascular disease (CVD) mortality in a low-risk cohort.

Assessing the Evidence of Aspirin for Primary Prevention in Diabetes

Assessing the Evidence of Aspirin for Primary Prevention in Diabetes

By

The substantial burden of cardiovascular disease in patients with diabetes has led to the exploration of various cardiovascular disease prevention strategies, including the use of aspirin.

Influence of Weight Loss, Resistance Training, and Aerobic Training on Bone Health

Influence of Weight Loss, Resistance Training, and Aerobic Training on Bone Health

By

Investigators assessed the effect of exercise modality during dietary-induced on bone health.

Antipsychotics Adversely Affect Adiposity and Insulin Sensitivity in Youths

Antipsychotics Adversely Affect Adiposity and Insulin Sensitivity in Youths

By

While antipsychotic treatments can improve behavioral symptoms, risk of hyperglycemia and weight gain should inform careful consideration of antipsychotic use in young patients.

Nutraceuticals May Benefit Patients Who Are Statin Intolerant

Nutraceuticals May Benefit Patients Who Are Statin Intolerant

By

Nutraceuticals may offer a solution to patients who cannot tolerate statins because of severe muscle pain.

In Teens, Young Adults, High BMI May Hurt Cardiovascular Health

In Teens, Young Adults, High BMI May Hurt Cardiovascular Health

Higher body mass index is likely to cause worse cardiovascular health in youth.

Nonfunctioning Adrenal Incidentaloma Associated With Metabolic Syndrome

Nonfunctioning Adrenal Incidentaloma Associated With Metabolic Syndrome

By

Investigators sought to determine the frequency of metabolic syndrome in patients with nonfunctioning adrenal incidentalomas.

Diabetes Screening Rates Suboptimal Among Patients With Rheumatoid Arthritis

Diabetes Screening Rates Suboptimal Among Patients With Rheumatoid Arthritis

By

Compliance with general population guidelines for diabetes screening was suboptimal among patients with rheumatoid arthritis.

'Good' Cholesterol May Not Be Good in Postmenopausal Women

'Good' Cholesterol May Not Be Good in Postmenopausal Women

High total HDL cholesterol in postmenopausal women may mask heart disease risk.

Metabolic Health Predicative of Cognitive Development in Children

Metabolic Health Predicative of Cognitive Development in Children

By

Researchers assessed whether current metabolic parameters are inversely associated with cognitive functioning.

Emotional Hyper-Reactivity and Cardiometabolic Risk in Remitted Bipolar Disorder

Emotional Hyper-Reactivity and Cardiometabolic Risk in Remitted Bipolar Disorder

By

Patients with remitted bipolar disorder and emotional hyper-reactivity also have significantly higher levels of low-grade inflammation, hypertension, and impaired glucose metabolism, indicating a higher risk for cardiometabolic dysfunction.

 USPSTF Does Not Recommend Electrocardiography Screening in Low-Risk CVD

USPSTF Does Not Recommend Electrocardiography Screening in Low-Risk CVD

By

The United States Preventive Services Task Force does not recommend screening with resting or exercise electrocardiography in asymptomatic individuals at low risk for cardiovascular disease events.

Osteoporosis Drug Shows Cardioprotective Potential at 10-Year Follow-Up

Osteoporosis Drug Shows Cardioprotective Potential at 10-Year Follow-Up

By

The 1-year cardiovascular mortality hazard ratio (HR) for alendronate users was 0.33 (95% CI, 0.17 to 0.65) and 0.55 for incident myocardial infarction (95% CI, 0.34 to 0.89).

Eplerenone May Improve Cardiovascular Disease Risk in HIV

Eplerenone May Improve Cardiovascular Disease Risk in HIV

By

Researchers investigated effects of eplerenone on insulin sensitivity, inflammatory indices, and other metabolic parameters in HIV.

Antipsychotics Increase Risk for Metabolic Syndrome, CVD in Younger Patients

Antipsychotics Increase Risk for Metabolic Syndrome, CVD in Younger Patients

By

Younger patients treated with antipsychotics after experiencing a first episode of psychosis are at an increased risk for metabolic syndrome and cardiovascular disease.

Aortic Stiffness, Concentric LV Remodeling Linked in Type 2 Diabetes

Aortic Stiffness, Concentric LV Remodeling Linked in Type 2 Diabetes

Researchers used multiparametric cardiovascular magnetic resonance imaging to examine the correlation between aortic stiffness and LV geometry in younger adults with type 2 diabetes.

Metabolic Syndrome and Skin Disorders: Association Is More Than Skin Deep

Metabolic Syndrome and Skin Disorders: Association Is More Than Skin Deep

By

Knowing that certain characteristics increase the risk for dermatology patients who may have metabolic syndrome will enable clinicians to identify patients who may have specific cardiovascular risks.

In LVSD, Diabetes Tied to Higher Risk of Heart Failure

In LVSD, Diabetes Tied to Higher Risk of Heart Failure

In patients with asymptomatic left ventricular systolic dysfunction, diabetes is associated with an increased risk of developing heart failure.

Metabolic Syndrome Frequency Assessed in Systemic Lupus Erythematosus

Metabolic Syndrome Frequency Assessed in Systemic Lupus Erythematosus

By

The frequency of metabolic syndrome among patients with SLE was approximately 45%.

Rheumatoid Arthritis Not as Likely to Increase CVD Risk as Diabetes

Rheumatoid Arthritis Not as Likely to Increase CVD Risk as Diabetes

Using both public and private health insurance claims data, investigators conducted a retrospective cohort study to assess cardiovascular risk in the setting of diabetes and rheumatoid arthritis.

Young Adults With Type 1 Diabetes Show Muscle Metabolic Deficiencies

Young Adults With Type 1 Diabetes Show Muscle Metabolic Deficiencies

Physically active young adults with type 1 diabetes have alterations in mitochondrial ultrastructure and bioenergetics within skeletal muscle.

Metabolic Syndrome Associated With Higher ALT Levels in Chronic Hepatitis B

Metabolic Syndrome Associated With Higher ALT Levels in Chronic Hepatitis B

By

Findings highlight the importance of screening for metabolic syndrome (MS) and the potential for MS to influence alanine aminotransferase and its interpretation in the context of HBV treatment decisions.

Sacubitril/Valsartan May Help Preserve Kidney Function in Patients With HFrEF

Sacubitril/Valsartan May Help Preserve Kidney Function in Patients With HFrEF

By

Compared with the enalapril-treated group, those treated with sacubitril/valsartan were found to have significantly slower kidney decline.

Soluble Klotho Levels Predictive of Kidney Failure in Type 2 Diabetes

Soluble Klotho Levels Predictive of Kidney Failure in Type 2 Diabetes

By

In patients with type 2 diabetes and with relatively preserved estimated glomerular filtration rate, reduced levels of soluble Klotho predict renal function decline independent of traditional risk markers.

FT3 Level Associated With the Development of Metabolic Syndrome

FT3 Level Associated With the Development of Metabolic Syndrome

By

Researchers designed a cohort study to examine whether serum thyroid hormone levels within the reference range are predictive factors for developing metabolic syndrome in adults.

Canagliflozin May Improve Renal Outcomes in Patients With Type 2 Diabetes

Canagliflozin May Improve Renal Outcomes in Patients With Type 2 Diabetes

By

The renal protective benefit was seen in patients with both reduced (eGFR <60mL/min/1.73m2) and preserved (eGFR ≥60mL/min/1.73m2) renal function.

Menopause Symptom Severity May Predict Heart Disease

Menopause Symptom Severity May Predict Heart Disease

By

Researchers examined whether menopausal symptoms, quality of life, and depression are related to arterial stiffness, a risk factor for cardiovascular disease.

Eating Pecans May Cut Risk for Cardiovascular Disease, Diabetes

Eating Pecans May Cut Risk for Cardiovascular Disease, Diabetes

Changes in serum insulin and homeostatic model assessment of insulin resistance and beta cell function were significantly greater compared to the control diet

Noninvasive CAD Screening May Reduce Cardiac Events in Individuals With Asymptomatic Diabetes

Noninvasive CAD Screening May Reduce Cardiac Events in Individuals With Asymptomatic Diabetes

By

Compared with standard care, noninvasive coronary artery disease screening reduced cardiac events by 27% in individuals with asymptomatic diabetes. Results justify larger, appropriately powered trials to potentially revisit current recommendations.

Sign Up for Free e-Newsletters



CME Focus