Cardiovascular and Metabolic Disorders

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Skin Disease and Metabolic Syndrome: Early Warning Signs of a Greater Problem

Skin Disease and Metabolic Syndrome: Early Warning Signs of a Greater Problem

Skin disorders, particularly those with known inflammatory mechanisms, may be considered potential early markers for the development of insulin resistance leading to metabolic syndrome, type 2 diabetes, and cardiovascular disease.

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Abdominal Adiposity in Adolescence Drives Cardiometabolic Dysfunction

Abdominal Adiposity in Adolescence Drives Cardiometabolic Dysfunction

Abdominal fatness in adolescence was associated with cardiometabolic dysfunction and BMI was found to be a beneficial tool for predicting effects of abdominal fat over time.

Metabolic Syndrome Highly Prevalent in Patients With Plaque Psoriasis

Metabolic Syndrome Highly Prevalent in Patients With Plaque Psoriasis

Metabolic syndrome and psoriatic arthritis were highly prevalent comorbidities in patients with plaque psoriasis.

Should Guidelines Use Higher Risk Thresholds When Recommending Statins for Primary CVD Prevention?

Should Guidelines Use Higher Risk Thresholds When Recommending Statins for Primary CVD Prevention?

Guidelines should incorporate using higher 10-year risk thresholds when recommending statins for the purpose of primary CVD prevention.

SYNTAX Score: A Predictive Scale for Adverse CV Events in Patients With Diabetes, CAD Undergoing PCI

SYNTAX Score: A Predictive Scale for Adverse CV Events in Patients With Diabetes, CAD Undergoing PCI

SYNTAX score, a validated prediction score used to estimate risk with PCI, is modestly correlated with hard cardiovascular events and is significantly correlated with major adverse cardiac and cerebrovascular events

Ezetimibe Plus Statins Modestly Reduce Cardiovascular Disease Event Risk

Ezetimibe Plus Statins Modestly Reduce Cardiovascular Disease Event Risk

Ezetimibe combined with statin therapy showed modest or moderate benefits in reducing major CVD event risk.

Omegaven Available for Pediatric Parenteral Nutrition-Associated Cholestasis

Omegaven Available for Pediatric Parenteral Nutrition-Associated Cholestasis

Fresenius Kabi announced the availability of Omegaven (fish oil triglycerides) injectable emulsion as a source of calories and fatty acids for pediatric patients with parenteral nutrition-associated cholestasis.

AHA: Statin Benefits Outweigh Risks

AHA: Statin Benefits Outweigh Risks

The data showed a <0.1% risk of statin-induced muscle injury, including rhabdomyolysis, and a ~0.001% risk of serious hepatotoxicity. Statin-induced newly diagnosed diabetes mellitus was a ~0.2% risk per year of treatment, depending on baseline risk in the patients studied.

Hypertensive Disorders in Pregnancy, Postpartum BMI Linked to T2D Risk

Hypertensive Disorders in Pregnancy, Postpartum BMI Linked to T2D Risk

Postpartum women with an elevated BMI score and a history of hypertensive disorders during pregnancy have an increased risk of developing type 2 diabetes.

Metabolically Healthy Obese Children, Adolescents at Higher Risk for CVD

Metabolically Healthy Obese Children, Adolescents at Higher Risk for CVD

Children and adolescents with metabolically healthy obesity had higher carotid intima-media thickness compared with metabolically healthy individuals who were a normal weight.

Plasma Acylcarnitines May Indicate Risk for Type 2 Diabetes

Plasma Acylcarnitines May Indicate Risk for Type 2 Diabetes

Among individuals at a high risk for cardiovascular disease, a panel of short- and long-chain acylcarnitines was significantly associated with the incidence of type 2 diabetes.

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