Cardiovascular & Metabolic Disorders

Cardiovascular Disease Risk Lower in Women With Type 2 Diabetes

Cardiovascular Disease Risk Lower in Women With Type 2 Diabetes

By

Investigators examined gender differences in baseline characteristics and outcomes in patients with t2d and ASCVD.

Improving Sleep Quality May Reduce Cardiovascular Risk in Bipolar Disorder

Improving Sleep Quality May Reduce Cardiovascular Risk in Bipolar Disorder

The relationship between circadian rhythm and sleep measures and components of metabolic syndrome in patients with bipolar disorder.

Depression May Be Associated With Metabolic Syndrome in Older Adults

Depression May Be Associated With Metabolic Syndrome in Older Adults

Older adults with metabolic syndrome experienced higher rates of depressive symptoms compared with older adults without metabolic syndrome.

Revised Pooled Cohort Equations for CVD Risk Improve Accuracy of Estimates

Revised Pooled Cohort Equations for CVD Risk Improve Accuracy of Estimates

Investigators revised pooled cohort equations to improve clinical accuracy to predict risk for cardiovascular disease.

Cardiovascular Outcomes in Patients With ACS, Diabetes Using Alirocumab

Cardiovascular Outcomes in Patients With ACS, Diabetes Using Alirocumab

By

Investigators examine the effects of the PCSK9 inhibitor alirocumab in patients with recent acute coronary syndrome and diabetes.

Elevated Triglycerides, Diabetes May Be Predictors of Major Cardiovascular Events

Elevated Triglycerides, Diabetes May Be Predictors of Major Cardiovascular Events

By

Investigators examined cardiovascular outcomes in patients with elevated triglyceridemia and diabetes treated with statins.

Good Sleep Tied to Better Cardiometabolic Health in Youths

Good Sleep Tied to Better Cardiometabolic Health in Youths

These results support the need to assess the role of sleep quantity and quality interventions as strategies for improving cardiovascular risk profiles of adolescents.

Sex Hormone Levels May Affect Postmenopausal Heart Disease Risk

Sex Hormone Levels May Affect Postmenopausal Heart Disease Risk

By

Researchers assessed the effect of testosterone, estradiol, dehydroepiandrosterone, and sex hormone-binding globulin levels on coronary heart disease, heart failure, and cardiovascular disease in postmenopausal women.

Fenofibrate Improves Cholesterol Levels in Type 2 Diabetes

Fenofibrate Improves Cholesterol Levels in Type 2 Diabetes

By

To understand the mechanism underlying the benefit of fenofibrate on vascular complications in patients with type 2 diabetes, investigators assessed carotid intima thickness as a marker of subclinical atherosclerosis.

Metabolic Health Maintenance Key to Preventing Cardiovascular Disease

Metabolic Health Maintenance Key to Preventing Cardiovascular Disease

By

Regardless of long-term metabolic health maintenance, obesity remains a risk factor for cardiovascular disease.

Thyroid Cancer Survivors at Higher Risk for Cardiovascular Disease

Thyroid Cancer Survivors at Higher Risk for Cardiovascular Disease

By

Investigators sought to assess the link between treatment for thyroid cancer and subsequent cardiac and vascular complications.

Depression, C-Reactive Protein, and Osteoprotegerin May Affect Dyslipidemia

Depression, C-Reactive Protein, and Osteoprotegerin May Affect Dyslipidemia

By

Investigators sought to determine whether serum lipid levels were associated with depression in patients with psychotic disorders.

Injectable Progestin-Only Contraceptives May Increase Risk for VTE

Injectable Progestin-Only Contraceptives May Increase Risk for VTE

By

Investigators examined the effect of progestin-only contraceptive on cardiometabolic outcomes, including stroke, MI, hypertension, diabetes, and VTE.

Improved calculations suggest major changes to statin, aspirin, and blood pressure medication prescribing

Updated risk calculations suggest that fewer people should be classified within the high-risk category for CVD.

Fewer Major Adverse Cardiovascular Events With New Antihyperglycemic Drugs With Lower Hypoglycemic Risk

Fewer Major Adverse Cardiovascular Events With New Antihyperglycemic Drugs With Lower Hypoglycemic Risk

By

Investigators proposed that reduction in MACE may be proportional to the magnitude of HbA1c reduction seen with newer antihyperglycemic agents.

Intensive LDL-C lowering reduces mortality in patients with higher baseline LDL-C

In this systematic review and meta-analysis, more intensive compared with less itensive LDL-C lowering was associated with a greater reduction in risk of total and cardiovascular mortality in trials of patients with higher baseline LDL-C levels.

Increased Risk for Mortality in People With Diabetes, CHD Taking Beta-Blockers

Increased Risk for Mortality in People With Diabetes, CHD Taking Beta-Blockers

By

Further studies are needed to assess whether beta-blockers are effective in reducing mortality and coronary events in patients with diabetes receiving optimal medical treatment.

Risk Factors for Cardiovascular Disease in Youth With Type 1 Diabetes

Risk Factors for Cardiovascular Disease in Youth With Type 1 Diabetes

By

Early treatment of cardiovascular disease risk factors such as dyslipidemia and hypertension will have long-term benefits with low risk and cost and should be more widely used in pediatric type 1 diabetes care.

Influence of Gender on Cardiovascular Risk and Glycemic Control in T1D

Influence of Gender on Cardiovascular Risk and Glycemic Control in T1D

By

Researchers assessed differences in glycemic control, major cardiovascular risk factors, diabetes-related complications, sexual dysfunction prevalence, and endothelial function in young men and women with type 1 diabetes.

Obesity May Increase Cardiovascular Morbidity, Mortality

Obesity May Increase Cardiovascular Morbidity, Mortality

Results provide critical perspective on cardiovascular disease associated with overweight and obesity and challenge both the obesity paradox as well as the view that overweight is associated with greater longevity.

Proliferative Diabetic Retinopathy Independently Associated With CVD in T1D

Proliferative Diabetic Retinopathy Independently Associated With CVD in T1D

By

Study found that the absence of proliferative diabetic retinopathy in those with stage 3b chronic kidney disease is associated with a lower prevalence of cardiovascular disease in patients with long duration of type 1 diabetes.

Prevalence, Effect of Undetected Diabetes in Percutaneous Coronary Intervention

Prevalence, Effect of Undetected Diabetes in Percutaneous Coronary Intervention

By

Abnormal glucose metabolism was detected in 1 out of 3 patients with nondiabetic percutaneous coronary intervention and was independently associated with a significantly higher event risk.

Sulfonylureas and Risk of Sudden Cardiac Arrest, Ventricular Arrhythmia Examined

Sulfonylureas and Risk of Sudden Cardiac Arrest, Ventricular Arrhythmia Examined

By

Study examined the association between individual antidiabetic sulfonylureas and outpatient-originating sudden cardiac arrest and ventricular arrhythmia.

Increased Adiposity Raises Myocardial Infarction Risk More in Women

Increased Adiposity Raises Myocardial Infarction Risk More in Women

Increases in waist circumference and waist-to-hip ratio are associated with a greater excess risk of myocardial infarction in women than men.

Effect of Fenofibrate Varies Widely in Type 2 Diabetes

Effect of Fenofibrate Varies Widely in Type 2 Diabetes

The method of individualized treatment effect prediction of fenofibrate on major cardiovascular events risk reduction in T2D can be used to guide clinical decision-making.

Predicting Mortality Following Acute Myocardial Infarction in Diabetes

Predicting Mortality Following Acute Myocardial Infarction in Diabetes

By

The acute-to-chronic glycemic ratio provided better prognostic insight with regard to in-hospital mortality and morbidity outcomes compared with glycemia levels at hospital admission in patients with diabetes who had an acute myocardial infarction.

Prior Authorization Requirements Greater for PCSK9 Inhibitors

Prior Authorization Requirements Greater for PCSK9 Inhibitors

Prior authorization requirements are greater for proprotein convertase subtilisin/kexin type 9 inhibitors than for other cardiometabolic drugs.

Case: A 67-Year-Old Man With Shortness of Breath After Wildfires

Case: A 67-Year-Old Man With Shortness of Breath After Wildfires

By

A patient living near an area experiencing frequent wildfires is concerned about the potential negative effect that the wildfires may have on his health.

T2D May Play a Protective Role Against Developing Aortic Diseases

T2D May Play a Protective Role Against Developing Aortic Diseases

By

The novel findings in this study suggest that patients with type 2 diabetes have a significantly reduced risk for short-term mortality after hospitalization for aortic aneurysm compared with population-based control subjects.

Reducing CV Risk in Patients With Rheumatoid Arthritis and Diabetes

Reducing CV Risk in Patients With Rheumatoid Arthritis and Diabetes

By

Abatacept conferred a greater reduction in cardiovascular risk compared with tumor necrosis factor inhibitors in patients with rheumatoid arthritis and diabetes.

Sign Up for Free e-Newsletters



CME Focus