Cardiovascular & Metabolic Disorders

LVAD in Heart Failure Linked to Improved Glycemic Control

LVAD in Heart Failure Linked to Improved Glycemic Control

By

HbA1c levels following left ventricular assist device implantation were statistically significantly lower than before surgery.

Genetic Testing Recommended for Familial Hypercholesterolemia

Genetic Testing Recommended for Familial Hypercholesterolemia

Genetic testing should become the standard of care for patients with definite or probable familial hypercholesterolemia.

Higher Aldosterone Levels Tied to Incident Type 2 Diabetes Risk

Higher Aldosterone Levels Tied to Incident Type 2 Diabetes Risk

Higher levels of aldosterone are associated with insulin resistance and incident type 2 diabetes among multiethnic individuals.

Widespread Statin Use Not Recommended in Old, Very Old

Widespread Statin Use Not Recommended in Old, Very Old

Statin use is not associated with reduced risk of atherosclerotic cardiovascular disease or all-cause mortality among older adults without type 2 diabetes.

Poststroke Statin Therapy Associated With Lower Risk for Osteoporosis, Fractures

Poststroke Statin Therapy Associated With Lower Risk for Osteoporosis, Fractures

By

A variety of underlying mechanisms may be attributed to the role of statins in preventing bone-related disorders.

Trends in Cardiovascular Deaths for US Adults With and Without Diabetes

Trends in Cardiovascular Deaths for US Adults With and Without Diabetes

By

Investigators used data from the National Health Interview Survey and follow-up mortality data to estimate trends and disparities in CVD.

Low Rates of Increasing Statin Doses After MI in Diabetes

Low Rates of Increasing Statin Doses After MI in Diabetes

By

Up-titration to a high-intensity statin occurred in only 37.7% of patients with diabetes after an acute myocardial infarction.

High Albumin-to-Creatinine Ratio Associated With Increased Risk for Microalbuminuria and Future CVD in Adolescents

High Albumin-to-Creatinine Ratio Associated With Increased Risk for Microalbuminuria and Future CVD in Adolescents

By

The association between albumin-to-creatinine ratio and risk for diabetic nephropathy and CVD was examined over 2 to 4 years.

CDC: More People With High Cholesterol Taking Medications

CDC: More People With High Cholesterol Taking Medications

There has been a substantial increase in the percentage of patients with high cholesterol over age 60 years taking lipid-lowering medications from 2005 to 2016, but such increases have not been seen among younger patients with high cholesterol.

Second-Line Sulfonylurea Therapy Linked to Cardiovascular Events in Type 2 Diabetes

Second-Line Sulfonylurea Therapy Linked to Cardiovascular Events in Type 2 Diabetes

By

Researchers assessed whether adding or switching to sulfonylureas is linked to increased risk for myocardial infarction, ischemic stroke, hypoglycemia, and all-cause mortality.

CVD Risk Independently Predicted by Poor Lifestyle Factors

CVD Risk Independently Predicted by Poor Lifestyle Factors

By

High BMI, low physical activity levels, and frequent smoking and high genetic risk increased the risk for atrial fibrillation, coronary artery disease, hypertension, stroke, and diabetes.

Statin Use and Cardiovascular Risk Perception Varies Among Races

Statin Use and Cardiovascular Risk Perception Varies Among Races

By

African American patients were less likely than white patients to be treated with any statin and at the guideline-recommended intensity.

Cardiovascular Disease Risk Lower in Women With Type 2 Diabetes

Cardiovascular Disease Risk Lower in Women With Type 2 Diabetes

By

Investigators examined gender differences in baseline characteristics and outcomes in patients with t2d and ASCVD.

Improving Sleep Quality May Reduce Cardiovascular Risk in Bipolar Disorder

Improving Sleep Quality May Reduce Cardiovascular Risk in Bipolar Disorder

The relationship between circadian rhythm and sleep measures and components of metabolic syndrome in patients with bipolar disorder.

Depression May Be Associated With Metabolic Syndrome in Older Adults

Depression May Be Associated With Metabolic Syndrome in Older Adults

Older adults with metabolic syndrome experienced higher rates of depressive symptoms compared with older adults without metabolic syndrome.

Revised Pooled Cohort Equations for CVD Risk Improve Accuracy of Estimates

Revised Pooled Cohort Equations for CVD Risk Improve Accuracy of Estimates

Investigators revised pooled cohort equations to improve clinical accuracy to predict risk for cardiovascular disease.

Cardiovascular Outcomes in Patients With ACS, Diabetes Using Alirocumab

Cardiovascular Outcomes in Patients With ACS, Diabetes Using Alirocumab

By

Investigators examine the effects of the PCSK9 inhibitor alirocumab in patients with recent acute coronary syndrome and diabetes.

Elevated Triglycerides, Diabetes May Be Predictors of Major Cardiovascular Events

Elevated Triglycerides, Diabetes May Be Predictors of Major Cardiovascular Events

By

Investigators examined cardiovascular outcomes in patients with elevated triglyceridemia and diabetes treated with statins.

Good Sleep Tied to Better Cardiometabolic Health in Youths

Good Sleep Tied to Better Cardiometabolic Health in Youths

These results support the need to assess the role of sleep quantity and quality interventions as strategies for improving cardiovascular risk profiles of adolescents.

Sex Hormone Levels May Affect Postmenopausal Heart Disease Risk

Sex Hormone Levels May Affect Postmenopausal Heart Disease Risk

By

Researchers assessed the effect of testosterone, estradiol, dehydroepiandrosterone, and sex hormone-binding globulin levels on coronary heart disease, heart failure, and cardiovascular disease in postmenopausal women.

Fenofibrate Improves Cholesterol Levels in Type 2 Diabetes

Fenofibrate Improves Cholesterol Levels in Type 2 Diabetes

By

To understand the mechanism underlying the benefit of fenofibrate on vascular complications in patients with type 2 diabetes, investigators assessed carotid intima thickness as a marker of subclinical atherosclerosis.

Metabolic Health Maintenance Key to Preventing Cardiovascular Disease

Metabolic Health Maintenance Key to Preventing Cardiovascular Disease

By

Regardless of long-term metabolic health maintenance, obesity remains a risk factor for cardiovascular disease.

Thyroid Cancer Survivors at Higher Risk for Cardiovascular Disease

Thyroid Cancer Survivors at Higher Risk for Cardiovascular Disease

By

Investigators sought to assess the link between treatment for thyroid cancer and subsequent cardiac and vascular complications.

Depression, C-Reactive Protein, and Osteoprotegerin May Affect Dyslipidemia

Depression, C-Reactive Protein, and Osteoprotegerin May Affect Dyslipidemia

By

Investigators sought to determine whether serum lipid levels were associated with depression in patients with psychotic disorders.

Injectable Progestin-Only Contraceptives May Increase Risk for VTE

Injectable Progestin-Only Contraceptives May Increase Risk for VTE

By

Investigators examined the effect of progestin-only contraceptive on cardiometabolic outcomes, including stroke, MI, hypertension, diabetes, and VTE.

Improved calculations suggest major changes to statin, aspirin, and blood pressure medication prescribing

Updated risk calculations suggest that fewer people should be classified within the high-risk category for CVD.

Fewer Major Adverse Cardiovascular Events With New Antihyperglycemic Drugs With Lower Hypoglycemic Risk

Fewer Major Adverse Cardiovascular Events With New Antihyperglycemic Drugs With Lower Hypoglycemic Risk

By

Investigators proposed that reduction in MACE may be proportional to the magnitude of HbA1c reduction seen with newer antihyperglycemic agents.

Intensive LDL-C lowering reduces mortality in patients with higher baseline LDL-C

In this systematic review and meta-analysis, more intensive compared with less itensive LDL-C lowering was associated with a greater reduction in risk of total and cardiovascular mortality in trials of patients with higher baseline LDL-C levels.

Increased Risk for Mortality in People With Diabetes, CHD Taking Beta-Blockers

Increased Risk for Mortality in People With Diabetes, CHD Taking Beta-Blockers

By

Further studies are needed to assess whether beta-blockers are effective in reducing mortality and coronary events in patients with diabetes receiving optimal medical treatment.

Risk Factors for Cardiovascular Disease in Youth With Type 1 Diabetes

Risk Factors for Cardiovascular Disease in Youth With Type 1 Diabetes

By

Early treatment of cardiovascular disease risk factors such as dyslipidemia and hypertension will have long-term benefits with low risk and cost and should be more widely used in pediatric type 1 diabetes care.

Sign Up for Free e-Newsletters



CME Focus