CARDENE IV Rx
Generic Name and Formulations:
Nicardipine HCl 2.5mg/mL; soln for slow IV infusion (after dilution to 0.1mg/mL).
Chiesi USA, Inc.
Indications for CARDENE IV:
Short-term treatment of hypertension when oral therapy is not feasible or desirable.
Individualize; see full labeling.
<18yrs: not recommended.
Advanced aortic stenosis.
Cardiac failure. Angina. Acute cerebral infarction or hemorrhage. Hepatic or renal impairment. Pheochromocytoma. For caps: measure blood pressure (BP) 1–2 hrs and 8 hrs after dosing. For IV: monitor BP before and during infusion; avoid rapid or excessive reductions; switch to oral form when possible. Pregnancy (Cat.C). Nursing mothers: not recommended.
Potentiated by cimetidine. Increases serum levels of cyclosporine, tacrolimus; monitor and adjust its dose. Possibly potentiates digoxin; monitor.
Calcium channel blocker (CCB) (dihydropyridine).
Increased angina, flushing (caps), headache, pedal edema, asthenia, dizziness, somnolence (caps), tachycardia, GI upset, sweating; ECG abnormalities, orthostatic hypotension, ventricular extrasystoles, local reactions (inj).
Caps 20mg, 30mg—contact supplier; IV (10mL amps)—10; Premixed—200mL
Endocrinology Advisor Articles
- GLP-1 Agonists Superior to DPP-4 Inhibitors for Reducing HbA1c, Weight in T2D
- Effect of HbA1c and Perioperative Glucose on Postoperative Mortality
- Semaglutide May Be Useful for Treating Obesity in People Without Diabetes
- Once-Daily Oral Contraceptive for Men Shows Promise
- Effect of Growth Hormone Treatment on BMD in Adults With Prader-Willi Syndrome
- American College of Physicians Releases 4 Guidelines for HbA1c Targets in T2D
- Dyslipidemia Drug Indications
- No Difference in Weight Loss Outcomes With Low-Fat vs Low-Carbohydrate Diet
- Damaging Effects of Gastric Bypass Surgery on Bone Mass and Microarchitecture
- Gastric Bypass Surgery Linked to Increased Risk for Nonvertebral Fractures
- Updated Clinical Practice Guidelines on Testosterone Therapy in Men With Hypogonadism
- Type 2 Diabetes Associated With Increased Fracture Risk in Postmenopausal Women
- Use of FSH in Early Diagnosis of Turner Syndrome
- Surgical Treatment Better Than Medical Therapy in Severely Obese Adolescents With T2D
- Metformin May Improve Pregnancy Outcomes in Polycystic Ovary Syndrome