Virginia Schad, PharmD

Investigators assessed the association of hepatitis B infection and pancreatic cancer, along with predictors of pancreatic cancer and mortality.

Cirrhosis is associated with an increased risk for diabetes mellitus among patients living with HIV.

Among a large US cohort of patients treated for HCV, patients who achieved sustained virologic response demonstrated a substantially lower risk for development of type 2 diabetes than patients with treatment failure.

IDegLira provides an efficacious intensification option with noninferior glycemic control vs basal-bolus in patients with type 2 diabetes receiving 20 to 50 units of basal insulin with no renal impairment and HbA1c levels of 7% to 10%.

Study provided evidence of significant differences in median serum concentrations of circulating adipose-related inflammatory biomarkers across the main diabetes types.

Researchers conducted a prospective, population-based cohort study to assess the risk for cardiovascular disease in postmenopausal women with increased androgen levels.

Testosterone therapy is recommended in men with hypogonadism to correct symptoms of testosterone deficiency. Men who are otherwise healthy do not need to be screened for hypogonadism.

Statins were associated with a reduction in mortality but there was no significant difference in the composite end point with fenofibrates alone or in combination with statins.

Study assessed cardiovascular function, quality of life, and mental/physical health in overt and cured Cushing syndrome.

Researchers have determined that treatment for osteoporosis with teriparatide is associated with greater bone formation than treatment with zoledronic acid.

Oral micronized progesterone may diminish hot flushes and night sweats in perimenopausal women, according to research presented at ENDO 2018.

A new birth control pill for men appears to be safe when used daily for a month, with hormone responses consistent with effective contraception.

In combination with dietary and physical activity counseling, all semaglutide doses from 0.05-0.4 mg daily were tolerated and resulted in dose-related reductions in body weight among people with obesity without diabetes.

A new study presented at ENDO 2018 finds that giving 1 year of estrogen replacement to female athletes with exercise-induced menstrual irregularities improves drive for thinness, body dissatisfaction, and uncontrolled eating.

Findings demonstrated a high incidence of sodium alterations in children following transsphenoidal surgery, with a 38% combined incidence of diabetes insipidus and syndrome of inappropriate antidiuretic hormone secretion.

Researchers investigated the effects of growth hormone vs placebo, as well as the effects of sex steroid replacement therapy on bone mineral density in growth hormone-treated young adults with Prader-Willi syndrome who had attained adult height.

Abnormal glucose metabolism was detected in 1 out of 3 patients with nondiabetic percutaneous coronary intervention and was independently associated with a significantly higher event risk.

Study suggests that single-hormone artificial pancreas systems may be sufficient for overnight control even in a high-risk group of hypoglycemia-unaware participants with documented nocturnal hypoglycemia.

Researchers compared the effects of combined metformin and COX-2 inhibitor therapy vs COX-2 therapy alone on joint replacement surgery rates.

Study assessed the efficacy and safety of insulin glargine 300 U/mL vs glargine 100 U/mL with and without concomitant DPP-4 inhibitor use in people with type 2 diabetes.

Researchers observed detrimental effects of RYGB on bone turnover, mass, structure, and strength just 6 months postoperatively, and these effects persisted throughout the duration of the 12-month study.

The novel findings in this study suggest that patients with type 2 diabetes have a significantly reduced risk for short-term mortality after hospitalization for aortic aneurysm compared with population-based control subjects.

Study assessed the effect of denosumab on bone mineral density and incident fractures in older adults with primary hyperparathyroidism who could not undergo or refused surgery.

This is the first study to have validated a metformin dose adjustment as a function of the estimated glomerular filtration rate in patients with type 2 diabetes and chronic kidney disease.

The bidirectional relationship between severe hypoglycemic events and cardiovascular outcomes suggests that there may be a common “frail” type 2 diabetes phenotype of patients who are susceptible to both of these events.

ADA’s recommendations reflect the latest advances in evidence-based research to improve care for millions of people with diabetes.

Study showed that parathyroid hormone was a significant predictor of lumbar spine bone mineral density Z-score for pseudohypoparathyroidism 1B patients.

Clinical guidelines should include postpartum screening and management for all cardiovascular risk factors in women diagnosed with gestational diabetes and not restrict it to diabetes.

Balance training interventions (supervised and unsupervised) led to significant improvements in a number of physiological measures, ultimately reflected in a decline in fall risk for older adults with T2D.

In patients with an acute coronary syndrome and LDL-C >50 mg/dL, healthcare providers should consider adding ezetimibe to statin therapy to reduce the risk of cardiovascular events.