Roxanne Nelson, BSN, RN

Closed-loop insulin administration appears to be better targeted and may be more effective in children with type 1 diabetes compared with sensor-augmented pump therapy.

Low-dose rituximab combined with a short course of intravenous methylprednisolone is an effective and safe alternative to high-dose steroids in thyroid eye disease.

Treatment with evolocumab significantly reduced low-density lipoprotein cholesterol but had no notable impact on glycemic measures in Chinese patients with type 2 diabetes and dyslipidemia.

Adult children of women who had gestational diabetes during pregnancy may have increased insulin resistance and be at risk for an atherogenic lipid profile.

Roux-en-Y gastric bypass worsens the inadequacy of micronutrients related to bone metabolism and is associated with secondary hyperparathyroidism and low bone mineral density values, particularly in adolescent patients.

The discontinuation of denosumab is associated with increased bone turnover markers and bone loss, but prior treatment with bisphosphonates did not seem to prevent the development of these complications.

A 50% to 80% basal rate reduction performed 90 minutes before beginning exercise will improve open-loop glucose control and decrease the risk for hypoglycemia during exercise in individuals with type 1 diabetes.

The association between precocious puberty and a wide range of preexisting medical conditions could provide additional insight into factors contributing to early pubertal onset.

An integrated collaborative care intervention resulted in modest improvements in weight loss and depressive symptoms in adults with obesity and depression.

Helicobacter pylori infection is associated with a higher risk for type 2 diabetes developing.

Lateral areal bone mineral density can identify microstructural heterogeneities that are independent of age and has advantages over anterior-posterior DXA scanning for fracture risk assessment.

Metformin can be safely prescribed to patients with diabetes and psoriasis.

Structural changes indicating diabetic nephropathy can occur very rapidly even with intensive glycemic control.

A higher body mass index was associated with increased deiodinase activity, which in turn was associated with higher levels of glucose during pregnancy.

Resting energy expenditure declined in adolescents 12 months after undergoing bariatric surgery, and metabolic adaptation was also negative from baseline.

Serum iodine levels appear to be associated with urinary iodine concentrations and thyroid function in pregnant women.

The short-term use of intravenous unacylated ghrelin infusion does not appear to have an effect on either substrate metabolism or insulin sensitivity in men with type 2 diabetes.

An earlier age of onset of puberty may be beneficial for adult bone density in Turner syndrome and type of hormone therapy may have a varying impact on adult health.

Treatment with sitagliptin had no effect on soluble CD14 when given to participants with virally suppressed HIV infection.

Compared with men, women who have diabetes experience greater changes in the cumulative burden of cardiovascular risk factors from young to middle-age adulthood.

Higher levels of vitamin D-binding protein at the time of delivery, but not during the middle of pregnancy, were associated with a lower risk for type 1 diabetes.

Both high and low niacin intake was associated with a risk for incident hip fractures in older adults.

Individuals with extreme insulin resistance have a high prevalence of thyroid nodules that do not appear to be associated with metreleptin treatment.

Both relative muscle strength and physical performance improved substantially in patients following Roux-en-Y gastric bypass surgery.

Introduction of the oral rotovirus vaccine in Australia was associated with a decline in the incidence of type 1 diabetes.

Children with normal timing of BMI peak who experienced an early adiposity rebound or without any BMI decline after infancy appear to have the highest risk of developing an adverse cardiometabolic profile in adolescence.

Increased glucose levels in middle-aged adults that include the development of diabetes are associated with a higher risk for cardiovascular disease.

Investigators evaluated whether treatment with one year of oral or transdermal administration of estrogen plus cyproterone and transdermal or intramuscular application of testosterone caused changes in serum lipids and blood pressure.

Genomic testing using next-generation sequencing may be advantageous in diagnosing patients born small for gestational age with persistent short stature.

Plasma testosterone levels are positively associated with overall body adiposity in postmenopausal women.