Closed-loop insulin administration appears to be better targeted and may be more effective in children with type 1 diabetes compared with sensor-augmented pump therapy.
Low-dose rituximab combined with a short course of intravenous methylprednisolone is an effective and safe alternative to high-dose steroids in thyroid eye disease.
Treatment with evolocumab significantly reduced low-density lipoprotein cholesterol but had no notable impact on glycemic measures in Chinese patients with type 2 diabetes and dyslipidemia.
Adult children of women who had gestational diabetes during pregnancy may have increased insulin resistance and be at risk for an atherogenic lipid profile.
Roux-en-Y gastric bypass worsens the inadequacy of micronutrients related to bone metabolism and is associated with secondary hyperparathyroidism and low bone mineral density values, particularly in adolescent patients.
The discontinuation of denosumab is associated with increased bone turnover markers and bone loss, but prior treatment with bisphosphonates did not seem to prevent the development of these complications.
A 50% to 80% basal rate reduction performed 90 minutes before beginning exercise will improve open-loop glucose control and decrease the risk for hypoglycemia during exercise in individuals with type 1 diabetes.
The association between precocious puberty and a wide range of preexisting medical conditions could provide additional insight into factors contributing to early pubertal onset.
An integrated collaborative care intervention resulted in modest improvements in weight loss and depressive symptoms in adults with obesity and depression.
Helicobacter pylori infection is associated with a higher risk for type 2 diabetes developing.
