Pascal G. Ferzli

Are You Confident of the Diagnosis? Familial cutaneous leiomyomatosis (FCL) is an autosomal dominant genetic disease. It presents with cutaneous and uterine leiomyomas and is associated with the development of renal cancer. Characteristic findings on physical examination See the Leiomyoma chapter for a description of leiomyomas. Typically multiple pink-to-red dermal papules and nodules with minimal…

Are You Confident of the Diagnosis? What to be alert for in the history Characteristic findings on physical examination Leiomyomas are rare benign tumors that derive from the proliferation of smooth muscle cells. They present as firm, skin colored, light brown or reddish brown papules less than 2cm in size in any distribution (solitary, clustered,…