Primary myelofibrosis/agnogenic myeloid metaplasia
Primary myelofibrosis/agnogenic primary myeloid metaplasia What every physician needs to know: Primary myelofibrosis (PMF) is a chronic malignant hematologic disorder that belongs to the family of Philadelphia chromosome negative myeloproliferative neoplasms. It is characterized by: splenomegaly, a leukoerythroblastic picture on peripheral smear, bone marrow fibrosis, cytopenias, and systemic symptoms. Approximately 60% of patients carry the…
