Physicians are calling on colleagues to bring up the cost of care and its potential impact when discussing treatment options with patients.

All articles by Jody A. Charnow
Novel treatments for metastatic prostate cancer have prolonged lives, but the survival benefits remain modest.
Pelvic lymph node metastases visualized on PSMA PET/CT prior to prostate cancer surgery independently predicts an increased risk for biochemical disease progression, a study found.
Strict management of secondary hyperparathyroidism may be necessary to improve prognosis in patients on dialysis who have coronary artery disease requiring percutaneous coronary intervention.
In a retrospective study, investigators found that radiofrequency ablation and parathyroidectomy for secondary hyperparathyroidism in patients on dialysis achieved intact parathyroid hormone levels in the target range in similar proportions of patients.
Case finding is more effective than population-based screening at identifying individuals with chronic kidney disease.
Patients with asymptomatic hyperuricemia who achieved serum uric acid levels of 6.0 mg/dL or less while on urate-lowering therapy had fewer gout flare episodes, a study found.
Elevated levels of serum oxalate in patients with type 2 diabetes on HD increase their risk for sudden cardiac death and other serious CV events.
Finding from a recent study could be used in patient counseling to promote healthier lifestyle choices to reduce the likelihood of prostate biopsy, according to investigators.
Lowest vs highest tertile of total hip BMD was significantly associated with a 2.2-fold increased risk for major adverse cardiovascular events, study finds.
Each 1 mg/dL rise in uric acid level was significantly associated with a 21% and 10% increased risk for cardiovascular and all-cause mortality, respectively, a study found.
Study reveals that almost 90% of men have hypogonadism at the time of hospital admission for COVID-19.
Obesity in men with metastatic castration-resistant prostate cancer is associated with decreased risks for all-cause and cancer-specific mortality compared with overweight and normal-weight men.
In a randomized controlled study, adding metformin to androgen deprivation therapy for low-tumor-volume metastatic hormone-sensitive prostate cancer significantly delayed development of castration-resistant disease.
In a study of Swedish women, gestational diabetes that progressed to type 2 diabetes was significantly associated with increased risks for chronic kidney disease and end-stage kidney disease.
In a study, renal transplant recipients in the lowest quartile of skeletal muscle attenuation had 2-fold increased risk for new-onset diabetes after transplantation.
Dapagliflozin, an oral SGLT2 inhibitor, decreased the risk of progression of focal segmental glomerulosclerosis compared with placebo, a subgroup analysis of the DAPA-CKD trial showed.
Increases in the proportion of red blood cells mediates the reduction in renal risks associated with SGLT2 inhibitor therapy in patients with type 2 diabetes and cardiovascular disease, a study found.
Visceral fat area was significantly associated with the risk for cardiovascular events and death and all-cause mortality, whereas coronary artery calcification score was not, a study found.
In a clinical trial, renal denervation was associated with decreased plasma renin activity and aldosterone levels compared with a sham procedure.
Investigators found the biggest declines in prostate, breast, and colorectal cancer screening rates among individuals in the Northeast US and those of higher socioeconomic status.
Whether successful treatment of depression reduces the risk for progression needs to be determined.
In the BETonMACE trial, CKD patients with type 2 diabetes who recently experienced acute coronary syndrome who received apabetalone had a significant 50% reduction in the risk for major cardiovascular events compared with placebo.
Finerenone vs placebo added to standard therapy was associated with a significant 18% reduction in the risk for major adverse kidney events in patients with both chronic kidney disease and type 2 diabetes mellitus.
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