Colby Stong

Colby Stong is the former editor of The Clinical Advisor and Neurology Reviews and is a freelance medical writer and editor living in central Pennsylvania.

All articles by Colby Stong

Individuals on PrEP who become infected with HIV, such as those with poor adherence to treatment, may have delayed seroconversion on blood-based and oral-fluid-based rapid antibody tests.2 In one study, oral antibody reactivity was first observed a median of 125 days (range, 14-547 days) after HIV RNA or antibodies were observed in the blood.13 In another study, individuals who received PrEP were 3.49 times more likely than those on placebo to experience a delay of >100 days in detecting the infection.14 Based on these and other findings in the literature, it has been suggested that laboratory-based serum or plasma HIV tests should be used whenever possible to monitor individuals on PrEP.2 Additionally, in the setting of known or suspected poor PrEP adherence, the threshold for augmenting p24/IgM/IgG assays with NAT should be lowered.2

Cardiovascular and Metabolic Disorders

Higher Plasma Lp(a), Family History of CHD an Additive CVD Risk Factor

Colby Stong

September 1, 2020

Elevated plasma levels of lipoprotein(a) and family history of coronary heart disease (CHD) were found to be associated with a risk for cardiovascular disease.

Next post in Cardiovascular and Metabolic Disorders

Colby Stong

All articles by Colby Stong

Higher Plasma Lp(a), Family History of CHD an Additive CVD Risk Factor

Assessing the Prevalence and Treatment of Severe Hypercholesterolemia