Amit Akirov, MD

Several genetic markers that were previously found to be associated with increased risk for type 2 diabetes may also affect the trajectory of glucose and insulin regulation during childhood.

Pheochromocytomas and paragangliomas may be an important cause of secondary osteoporosis.

Improving environment supportiveness may have a substantial impact on hypothalamic-pituitary-adrenocortical axis and stress-mediating systems in children.

Weight gain after smoking cessation partially attenuates the beneficial effect on cardiovascular morbidity.

Researchers assessed the efficacy and safety of different antihyperglycemic agents in patients with nonalcoholic fatty liver disease.

Reduction of triglycerides with volanesorsen therapy may significantly improve the clinical symptoms and quality of life in patients with familial chylomicronemia syndrome.

Researchers explored the effects of a telemedicine visit on care in patients with T1D.

Adolescence and emerging adulthood represent a complicated stage for patients with T1D. Access to mental health services during this transition is critical.

Inclusion of hemoglobin A1c as a factor in cardiovascular disease risk prediction scores only had modest benefit.

In one of the first studies to explore the interrelationships between hormones from different hypothalamic-pituitary-target gland axes over 24 hours, there was evidence of interaction between distinct hormonal axes.

In patients with diabetes and high cardiovascular risk, hemoglobin A1c is strongly associated with cardiovascular outcomes.

Several routinely assessed blood tests in children may be significantly affected by obesity.

The researchers suggest including information about bone-healthy lifestyle in the management of PLWHIV, as well as earlier initiation of osteoporosis prophylaxis and treatment.

Boys born small for gestational age are at a higher risk for infertility in adulthood.

Randomized controlled trials demonstrate no fracture risk reduction with vitamin D supplements alone, according to findings from a meta-analysis.

Low HDL-C may be used to monitor long-term average triglycerides and remnant cholesterol levels, similar to how high hemoglobin A1c is used to monitor long-term elevated glucose levels.

Assessment of suicide risk as part of routine pediatric type 1 diabetes care is feasible and necessary.

Older men receiving testosterone treatment with higher waist-to-hip ratio experience greater increases in noncalcified coronary plaque volume.

Extreme body weights associated with either anorexia nervosa or obesity may affect bone mineral density and bone remodeling in young women.

Resistance exercise alone or in combination with aerobic exercise was found to be better than aerobic exercise alone in reducing weight loss-induced decreases in hip BMD.

Researchers examined the association between bariatric surgery and risk for colon and rectal cancer over time.

The risk for type 1 and type 2 diabetes from childhood into adulthood is increased in preterm-born individuals.

Children of women with diabetes diagnosed before or during pregnancy are at increased risk for early-onset cardiovascular disease.

Time of thyroid function sampling may affect the diagnosis of subclinical thyroid dysfunction in patients with acute myocardial infarction.

Treatment with SGLT2 inhibitors empagliflozin and dapagliflozin may be associated with less decline in kidney function across different chronic kidney disease stages.

Researchers identified a network of lipid species jointly associated with markers of both osteoporosis and atherosclerosis.

Researchers found no association between subclinical thyroid dysfunction and bone mineral density in healthy middle-aged adults.

Significant changes in bone mass may occur after stroke and are more pronounced in the paretic limbs and during the first few months after the acute event.

The high prevalence of overweight and obesity in youth with T1D was consistent across a multinational cohort and persistent over time.

Premature menopause, defined as either surgical or natural menopause before 40 years of age, is associated with an increased risk for cardiovascular disease.