Amit Akirov, MD

Greater alcohol consumption is associated with lower serum bone formation markers in patients living with HIV.

Treatment with zoledronic acid may be associated with an increased risk for heart failure, fracture, and mortality compared with the use of oral bisphosphonates or no treatment.

Consumption of sugar-sweetened beverages is associated with adverse changes in lipid profiles.

The American Association of Endocrine Surgeons has published the first comprehensive guidelines for safe, effective, and appropriate thyroidectomy.

There is a close association between sarcopenia and diabetic peripheral neuropathy.

The level of MFSD2a in maternal blood is a possible biomarker for disturbances of MFSD2a gene expression and may assist in predicting fetal neurodevelopment.

Bone metastases are present in more than a quarter of patients with metastatic medullary thyroid carcinoma, most often with an osteolytic morphology.

Among patients with obesity and migraine, weight loss is associated with reduction of migraine frequency, pain severity, and attack duration and disability.

In the management of PNETs it is important to differentiate between functional and nonfunctional PNETs in order to determine the course of treatment.

Thermal ablation techniques, including radiofrequency, laser, and microwave ablation, are relatively safe and effective for the treatment of papillary thyroid microcarcinoma.

Hemoglobin glycation index quantifies the magnitude and direction of interindividual variations in HbA1c that can be attributed to factors other than blood glucose levels.

Severe vitamin D deficiency was linked to lumbar degenerative disease and low back pain in postmenopausal women.

Various adipokine and cytokine concentrations may be helpful in predicting the risk for incident diabetes in healthy adults without diabetes.

In postmenopausal women with osteoporosis, 2 doses of zoledronate 5 mg at an approximately 6-year interval prevented bone loss for almost 11 years.

Individuals with hypercholesterolemia without an identifiable genetic cause may be at a relatively lower risk for CVD than those with monogenic or polygenic etiologies.

Direct oral anticoagulants are an effective and safe alternative to warfarin treatment for patients with nonvalvular atrial fibrillation and hyperthyroidism.

In most cases of overt hyperthyroidism, patients present with a constellation of symptoms, and appropriate treatment depends on the underlying mechanism.

A continuous behavioral lifestyle intervention supported by a smartphone app can assist in improving dietary intake and physical activity among pregnant women with overweight and obesity.

The association between rosiglitazone and increased cardiovascular risk, especially heart failure, was supported in a set of meta-analyses.

With the use of age-adjusted thresholds for noninvasive markers of liver steatosis and fibrosis, patients with type 2 diabetes may be referred more efficiently to specialists.

A novel dual-hormone artificial pancreas system that delivers both rapid insulin and pramlintide was found to improve glucose control.

In patients with venous thromboembolism, morbid obesity was associated with lower mortality risk.

Oral bisphosphonate treatment was not associated with increased all-cause mortality risk in patients with moderate to severe chronic kidney disease.

Chronic pancreatitis is associated with increased risk for diabetes-associated emergencies, including diabetic ketoacidosis.

Longer breastfeeding duration may protect against obesity in early childhood, while early introduction of solid foods may increase the risk for obesity.

The use of calcium dietary supplements was found to be associated with slower decline in femoral neck and lumbar spine bone mineral density across the menopausal transition.

Treatment with intravenous glucose-dependent insulinotropic polypeptide had no acute beneficial effects on appetite, energy intake, or energy expenditure in type 2 diabetes.

Higher gamma-glutamyltransferase variability was found to be significantly associated with increased risk for dementia among patients with diabetes.

Skeletal maturation is significantly delayed in boys with glucocorticoid-treated Duchenne muscular dystrophy.

Menopause is linked to unfavorable health effects in women with type 2 diabetes, but older age at menarche may be associated with a decrease in these adverse effects.