Amit Akirov, MD

Current clinical management may contribute to overdiagnosis and overtreatment of subclinical hypothyroidism during pregnancy and postpartum.

In patients with classical congenital adrenal hyperplasia, the use of modified-release hydrocortisone may improve biochemical control.

Cross-sex hormone therapy may have a negative effect on lipid profile and glucose levels in transgender men but not in transgender women.

Kisspeptin might play a role in ovulation and successful pregnancy in patients with infertility who undergo in vitro fertilization.

Switching from daily human growth hormone to once-weekly TransCon growth hormone treatment resulted in similar safety and efficacy outcomes in pediatric patients.

A trial of combination therapy with LT4 and LT3 may be used for patients with hypothyroidism who have not benefited from LT4 alone.

Elevated hemoglobin A1c before conception is associated with increased risk for maternal morbidity among women without preexisting diabetes.

The use of bone-specific drugs, such as those for osteoporosis treatment, is linked to an increased risk for osteonecrosis of sites other than the jaw.

A scientific statement from the National Lipid Association outlines the implications of genetic testing in patients with dyslipidemia.

Pregnancy loss and recurrent pregnancy losses are strongly and consistently associated with an increased risk for later type 2 diabetes.

Treatment with statins for cardiovascular risk reduction is associated with higher levels of insulin resistance in older community-dwelling adults.

Phentermine and topiramate may aid in the efforts to reduce the occurrence of rapid weight regain after Roux-en-Y gastric bypass surgery.

Pathological brain lesions are not common on MRI in girls with central precocious puberty in the absence of signs or symptoms of CNS lesions.

High body weight variability may be associated with increased risk for all-cause dementia and Alzheimer dementia in older patients.

In Mendelian randomization analyses, obesity was not causatively linked to either benign nodular thyroid disease or thyroid cancer.

Prediabetes is not associated with cognition after stroke, whereas type 2 diabetes increases the risk for lower poststroke cognitive function.

Adolescents with obesity or type 2 diabetes are at increased risk for progression of cardiovascular risk factors and accelerated early vascular aging.

Increased weight loading was found to reduce body weight and fat mass, supporting the concept of a loading-dependent regulation of body weight.

Oocyte fatty acid composition differs between women with normal weight vs overweight or obesity and may be related to poor IVF outcomes.

Several cardiac and kidney biomarkers may be used to identify older adults with peripheral neuropathy.

Healthcare systems in New York City have partnered to support vulnerable children with obesity using a telehealth weight management program.

Experts provide recommendations for effective implementation of telehealth for diabetes care, with a focus on patient-to-clinic video encounters.

An analysis of DPP-4 inhibitors alone or with basal insulin showed that they are safe and effective for hospitalized patients with type 2 diabetes.

Management of women at increased risk for hereditary gynecologic cancer must take into consideration concerns about fertility and hormonal health.

Sleep-disordered breathing and fragmented sleep are associated with higher levels of fasting glucose and hemoglobin A1c in black adults.

Fasting hyperglycemia on the next day following mechanical thrombectomy for acute ischemic stroke is associated with worse outcomes at 3-months.

In patients with autoimmune Addison disease, there is a rapid decline in steroidogenic capacity once replacement glucocorticoid medication is started.

Age-related declines in percentage of lean body mass over time are associated with a higher risk for diabetes among healthy older men.

A narrative review summarizes recent data on the pathophysiology, epidemiology, and burden of disease and treatment of menstrual migraine.

In most cases, fine needle aspiration biopsy of thyroid nodules should be deferred to a later time when risk for COVID-19 exposure is lower.