Anti-CD20 Therapy for Immune-Mediated Diseases Linked to Increased Mortality Risk in COVID-19
Researchers examined whether treatment with CD20 inhibitors resulted in worse COVID-19 outcomes among patients with immune-mediated diseases.
All articles by Amit Akirov, MD
Does the Association of Fasting Blood Glucose With Stroke Risk Differ by Race and Sex?
Researchers investigated the sex and race differences in the association between fasting blood glucose and the risk for ischemic stroke in adults aged 45 years and older.
Reduced Efficacy of SARS-CoV-2 mRNA Vaccines in Patients With CD20 B-Cell-Depleting Treatment History
Researchers assessed the humoral and cell-mediated immune responses to SARS-CoV-2 mRNA-based vaccines in patients with a history of receiving CD20-targeted B-cell-depleting therapy.
Study Reveals Histopathologic Findings in the Muscle and Nerve in Patients With Severe COVID-19
Researchers analyzed the autopsies of patients who died from COVID-19 to understand the pathophysiology of COVID-19-related myopathy.
Does Anakinra Have a Role in the Treatment of Severe COVID-19?
Authors of a commentary assessed the role of IL-1 receptor antagonism, specifically anakinra, in the treatment of patients with severe COVID-19.
What Is the Optimal Surgical Approach to Thymectomy in Myasthenia Gravis?
This meta-analysis of studies comparing 2 or more surgical approaches vs thymectomy aimed to identify the best option for myasthenia gravis patients.
Knowledge Gap Exists on Combined Treatment Efficacy Assessed by Bone Biomarkers in Osteoporosis and Osteopenia
Study authors conducted a systematic review to assess the impact of physical activity interventions in combination with pharmacologic treatments on bone turnover biomarkers in patients with osteopenia and osteoporosis.
Inflammatory Arthritis Associated With Reduced Fertility in Men
Researchers evaluated the impact of inflammatory arthritis on several male fertility outcomes, including fertility rate and family planning.
Anakinra Reduces Need for Mechanical Ventilation and Mortality Risk in Hospitalized Nonintubated Patients With COVID-19
In this meta-analysis, study authors showed that treatment with anakinra reduced the need for invasive mechanical ventilation and mortality risk in hospitalized nonintubated patients with COVID-19.
Prior Falls, Low Grip Strength, and Elevated HbA1c Predict Fractures in Older Adults With Type 2 Diabetes
Researchers identified the clinical characteristics of fragility fractures among older adults with type 2 diabetes, in the Framingham Heart Study.
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