Androgen and Reproductive Disorders
Preconception hyperandrogenism and impaired glucose tolerance are predictive of multiple obstetric and perinatal complications in women with PCOS.
Despite research suggesting that there may be increased cardiovascular risk from off-label prescription testosterone use, usage in men with coronary artery disease remains higher than in men without coronary artery disease.
A study was conducted to assess the safety, tolerability, and efficacy of methyl estradiolpropanoate, a topical soft estrogen cosmeceutical for the treatment of estrogen-deficient skin.
Oral preparations of hormone replacement therapy for the treatment of menopausal symptoms are associated with a greater risk for VTE compared with transdermal formulations.
Women born with a low birth weight have an increased risk for pregnancy complications.
Higher serum total testosterone in men and androstenedione in young men may increase the risk for anxiety disorders.
Three novel loci have been identified for polycystic ovary syndrome.
Internationally, infertility is ranked as the fifth most serious disability among women.
Vaginal estrogen use or nonuse did not carry different risks for cardiovascular outcomes, cancer outcomes, or hip fracture.
The U.S. Food and Drug Administration is implementing a number of steps for long-term safety monitoring of the permanent birth control device Essure, which will no longer be sold or distributed in the United States after Dec. 31, 2018.
Postmenopausal women with edentulism are at an increased risk for developing hypertension.
Almost two-thirds of U.S. women aged 15 to 49 years were currently using contraception in 2015 to 2017.
Intimate partner violence, sexual assault, and symptoms of posttraumatic stress disorder may be associated with menopause symptoms.
Providers should maximize women's health during the interpregnancy period, continuing care beyond the immediate postpartum period.
Men who use androgenic anabolic steroids have an increased mortality risk, a notable increase in hospitalizations, and higher prevalence of certain disorders compared with the general population.
A longer duration of infertility was associated with lower sperm concentrations and higher rates of azoospermia in men with primary infertility.
Fetal exposure to famine is associated with an increased risk for early menopause.
A high BMI is associated with reduced follicle-stimulating hormone receptor expression in human chorionic gonadotropins, reduced expression of estradiol synthesis-related genes, and reduced production of estradiol.
Oxybutynin, an anticholinergic used to treat urinary incontinence, may provide breast cancer survivors with an alternative treatment option for hot flashes, according to new research.
Phase 3 trial results assessing the intrauterine system, Liletta (levonorgestrel 52 mg), found that it had >99% efficacy in preventing pregnancy for up to 5 years; the products current Food and Drug Administration indication.
Exposure to certain endocrine disrupting chemicals may impact timing of puberty in children.
To investigate the association between hormone therapy and carpal tunnel syndrome risk, researchers conducted a secondary analysis of the Women's Health Initiative (WHI) hormone therapy trials.
Severe vulvovaginal atrophy (VVA) symptoms are associated with worse quality of life in postmenopausal women.
Drospirenone is a spironolactone analogue with antimineralocorticoid and antiandrogenic activity.
Women who undergo surgical menopause have significantly worse sleep quality than those who experience natural menopause.
Prior to starting Xyosted, the patient's baseline cardiovascular risk should be considered and blood pressure should be adequately controlled.
The year-long Phase 2b trial, funded by the National Institutes of Health, will enroll approximately 420 couples that are seeking pregnancy prevention across 3 US sites (Los Angeles, Seattle, and Kansas City).
In a select sample of men, testosterone treatment in higher doses was observed to be effective for reducing depressive symptoms.
In older men with low testosterone concentrations, testosterone therapy improves self-reported walking ability and outcomes on the 6-minute walking test.
In addition to the risk that children with CPP will not reach their adult height potential, a range of studies have noted a high risk for psychological, social, and behavioral problems in this population.
Endocrinology Advisor Articles
- Testosterone Use Remains High Among Men With Coronary Artery Disease
- Higher Risk for Venous Thromboembolism With Oral vs Transdermal HRT
- Comparing Osteoporosis Screening, Treatment Strategies in Postmenopausal Women
- Maternal Thyroid Function in Pregnancy Linked to Childhood Risk for Disease
- Primary Characteristics of PCOS Predictive of Obstetric Complications
- ADA's 2019 Standards of Medical Care in Diabetes Focus on Patient-Centered Care
- Sleep Habits Affect Insulin Sensitivity in Adolescents With Overweight, Obesity
- Levothyroxine Associated With Increased Mortality in Patients With Heart Failure
- Head-to-Head Comparison of Professional vs Personal CGM Systems in T1D
- Dual vs Triple Therapy for Metformin Treatment Intensification in Type 2 Diabetes
- Insulin Analogs vs Regular Human Insulin for Type 2 Diabetes
- Diabetic Ketoacidosis May Affect Brain Development in Children With T1D
- Higher Rates of Comorbidities Among Holocaust Survivors
- Population Health Data May Help Identify Patients at Risk for CVD
- Newborn Genomic Sequencing Can Identify Disease Risk