Androgen & Reproductive Disorders

Metformin and PCOS: Improving Menstrual Cycle and Hormone Profiles

Metformin and PCOS: Improving Menstrual Cycle and Hormone Profiles

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Variable improvements in menses, hormones, and metabolism were seen during 24 months of metformin use in 119 women with PCOS sub-grouped by baseline weight and androgen status.

Pregnancy Rates in Women Undergoing IVF With Fresh vs Frozen Embryos

Pregnancy Rates in Women Undergoing IVF With Fresh vs Frozen Embryos

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Study evaluated the difference in the rate of ongoing pregnancy or live birth between frozen embryo transfer and fresh embryo transfer in women without polycystic ovary syndrome who were undergoing IVF.

Air Pollution May Increase Likelihood of Menstrual Irregularity

Air Pollution May Increase Likelihood of Menstrual Irregularity

Exposure to air pollution during high school is associated with a slightly higher likelihood of menstrual irregularity and longer time to regularity.

FDA Approves Somatropin Injection to Treat Growth Hormone Deficiency

FDA Approves Somatropin Injection to Treat Growth Hormone Deficiency

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The FDA has approved Zomacton, a somatropin injection, for the replacement of growth hormone in adults with GH deficiency.

States Have Considerable Disparity in High-Quality LARC Service Delivery

States Have Considerable Disparity in High-Quality LARC Service Delivery

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Medicaid policy encourages the use of long-acting reversible contraception, but state-level payment policies are inconsistent and often do not include critical aspects of care.

Hyperandrogenism May Affect Gut Microbiome Changes in PCOS

Hyperandrogenism May Affect Gut Microbiome Changes in PCOS

Researchers have found that lower alpha diversity is seen in women with polycystic ovary syndrome vs healthy women.

Estrogen Contraceptives May Increase Stroke Risk in Women With Migraine

Estrogen Contraceptives May Increase Stroke Risk in Women With Migraine

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Women with migraine with aura are at an increased risk for stroke if they are taking high-dose estrogen-containing contraceptives.

Stair-Step Clomiphene Protocol Linked to Decreased Ovulation Time in PCOS

Stair-Step Clomiphene Protocol Linked to Decreased Ovulation Time in PCOS

The stair-step clomiphene protocol is associated with decreased time to ovulation for women with polycystic ovary syndrome.

Nonhormonal Options Available for Menopause Symptom Relief

Nonhormonal Options Available for Menopause Symptom Relief

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A nonhormonal treatment option for the relief of symptoms associated with menopause is now available alongside other drug-free supplements.

Live-birth rates similar among ovulating women undergoing fresh- or frozen-embryo transfer

No differences were observed in live-birth rate, rates of implantation, clinical pregnancy, overall pregnancy loss, or ongoing pregnancy incidents between ovulatory women with infertility who received frozen-embryo or fresh-embryo transfers.

USPSTF's Final Recommendation on Menopausal HT for Chronic Disease Prevention

USPSTF's Final Recommendation on Menopausal HT for Chronic Disease Prevention

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To update its 2012 recommendation, the US Preventive Services Task Force reviewed evidence on the benefits and harms of systemic hormone therapy for the prevention of chronic conditions in postmenopausal women.

For Postmenopausal Women, Breast Cancer Risk Reduced With Modest Weight Loss

For Postmenopausal Women, Breast Cancer Risk Reduced With Modest Weight Loss

Researchers found that 3061 postmenopausal women of 61,335 developed invasive breast cancer during a mean follow-up of 11.4 years. Women with weight loss (≥5%) had a significantly lower breast cancer risk than women with stable weight.

Unapproved Drugs, Substances in Androgen Receptor Modulators Sold Online

Unapproved Drugs, Substances in Androgen Receptor Modulators Sold Online

Products marketed as selective androgen receptor modulators and sold via the internet frequently contain unapproved drugs and substances, and the amount of active compound often does not match that listed on the label.

Fertility Hormone Therapy and Cardiovascular Outcomes: What We Know

Fertility Hormone Therapy and Cardiovascular Outcomes: What We Know

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Although the use of fertility therapy has steadily increased in the past few decades, research findings pertaining to related long-term cardiovascular outcomes are scarce and conflicting.

Guideline for Metformin Use for Ovulation Induction in PCOS

Guideline for Metformin Use for Ovulation Induction in PCOS

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Guideline was developed under the direction of the Practice Committee of the American Society for Reproductive Medicine.

Long-Term Progestin-Only Oral Contraceptives Reduce Pelvic Girdle Pain

Long-Term Progestin-Only Oral Contraceptives Reduce Pelvic Girdle Pain

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Long-term exposure to progestin-only oral contraceptives or to a progestin intrauterine device is associated with a small beneficial effect on pelvic girdle pain.

Does Asthma Contribute to Infertility?

Does Asthma Contribute to Infertility?

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Asthma may increase the likelihood of a woman needing fertility treatments prior to becoming pregnant.

Obesity Linked to Low Sperm Quality, Semen Volume

Obesity Linked to Low Sperm Quality, Semen Volume

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Obese men have lower semen volume, number, concentration, and motility, as well as a higher prevalence of oligospermia and asthenospermia.

Ovarian Reserve Biomarkers Not Indicative of Reduced Fertility

Ovarian Reserve Biomarkers Not Indicative of Reduced Fertility

Predicted probability of conception was not significantly lower for women with low antimüllerian hormone vs those with normal hormone levels.

Treating Endometriosis-Related Pain With Ethinylestradiol/Drospirenone Regimen

Treating Endometriosis-Related Pain With Ethinylestradiol/Drospirenone Regimen

Researchers examined the efficacy of FlexibleMIB (ethinylestradiol/drospirenone) vs placebo as therapy for endometriosis-related pain.

Predicting Metabolic Dysfunction in PCOS Through Acne, Hirsutism

Predicting Metabolic Dysfunction in PCOS Through Acne, Hirsutism

While hirsutism may indicate metabolic abnormalities, acne and androgenic alopecia are associated with other clinical hyperandrogenism manifestations.

Compounded Bioidentical Hormone Therapy in Menopause: Clinician Caution Advised

Compounded Bioidentical Hormone Therapy in Menopause: Clinician Caution Advised

Rates of cBHT prescriptions are not yet being systemically tracked, and few data exist to demonstrate the safety, efficacy, or utility of the treatment.

Endocrine Treatment in Transgender Individuals: Guidelines in Brief

Endocrine Treatment in Transgender Individuals: Guidelines in Brief

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The newly released guidelines include updated language to reflect DSM-V changes, greater flexibility in treatment, and recommendations for CVD, bone health, and prostate cancer screening.

Does Transdermal Estrogen Improve Sexual Function in Early Postmenopause?

Does Transdermal Estrogen Improve Sexual Function in Early Postmenopause?

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The Female Sexual Functioning Index was used to assess aspects of sexual function and experience in early postmenopausal women.

Does PCOS Increase T2D Event Rate?

Does PCOS Increase T2D Event Rate?

Among women with polycystic ovary syndrome, type two diabetes was more common and diagnosed at a younger age than in control groups.

Ethical Considerations in Publicly Funded Fertility Treatment

Ethical Considerations in Publicly Funded Fertility Treatment

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High costs associated with in vitro fertilization create barriers to fertility treatments that many cannot overcome.

Pregnancy Complications in Hyperandrogenic PCOS: What Are The Risks?

Pregnancy Complications in Hyperandrogenic PCOS: What Are The Risks?

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Hyperandrogenic PCOS is associated with maternal pregnancy complications, including gestational diabetes.

FDA Approves Treatment for Menopause Associated Dyspareunia

FDA Approves Treatment for Menopause Associated Dyspareunia

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Intrarosa, the first FDA approved local, non-estrogen product for treating dyspareunia, is now available.

ACOG: Guidelines for Teen Contraception Counseling

ACOG: Guidelines for Teen Contraception Counseling

Contraception conversations should take place as early as is appropriate.

AACE/ACE Updated Position Statement on Menopause

AACE/ACE Updated Position Statement on Menopause

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Although the updated statement does not change the recommendations outlined in previous treatment guidelines, the authors have added 8 new recommendations based on evidence that has emerged in the interim.

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