Androgen & Reproductive Disorders

Undiagnosed Prediabetes Prevalent in Men With Primary Infertility

Undiagnosed Prediabetes Prevalent in Men With Primary Infertility

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Approximately 15% of men experiencing infertility may have undiagnosed prediabetes.

Cardiometabolic Disease Patterns Related to Race, Ethnicity in Midlife Women

Cardiometabolic Disease Patterns Related to Race, Ethnicity in Midlife Women

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Women entering menopause had patterns of cardiometabolic risk components related to race/ethnicity.

Oral Contraceptives Recalled Due to Incorrect Dispenser Instructions

Oral Contraceptives Recalled Due to Incorrect Dispenser Instructions

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Without proper instructions for the correct use of the Veridate dispenser pack, the patient may take the pills in the wrong order or may take an inactive "reminder" pill vs an "active" pill.

Early Natural Menopause Linked to Life Expectancy, Years With T2D

Early Natural Menopause Linked to Life Expectancy, Years With T2D

Compared with women who experience normal or late menopause, women who experience early natural menopause have a shorter life expectancy and spend fewer years without type 2 diabetes.

Bijuva Approved for Moderate to Severe Vasomotor Symptoms Due to Menopause

Bijuva Approved for Moderate to Severe Vasomotor Symptoms Due to Menopause

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Approval from the Food and Drug Administration (FDA) was supported by the Phase 3 Replenish trial which evaluated the safety and efficacy of Bijuva in generally healthy, postmenopausal women with a uterus for the treatment of moderate to severe hot flashes.

Is BPA Safe? Endocrine Society Addresses FDA Position on Commercial BPA Use

Is BPA Safe? Endocrine Society Addresses FDA Position on Commercial BPA Use

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The Endocrine Society has expressed concern regarding the FDA's position on use of BPA in commercial products.

Atherosclerosis Progression Differs According to Timing of Estradiol Therapy After Menopause

Atherosclerosis Progression Differs According to Timing of Estradiol Therapy After Menopause

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Higher levels of estradiol were inversely associated with carotid artery intima-media thickness progression in the early postmenopausal cohort but positively associated with it in the late postmenopausal group.

Fertility Rates Decreasing in US for All Urbanization Levels

Fertility Rates Decreasing in US for All Urbanization Levels

During 2007 to 2017, fertility rates decreased in the United States for each urbanization level.

Effects of Testosterone Replacement Therapy in Men With COPD

Effects of Testosterone Replacement Therapy in Men With COPD

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Middle-aged testosterone replacement therapy users with COPD had a greater reduction in hospitalizations compared with nonusers.

Levonorgestrel-Releasing Intrauterine System Approved for 5-Year Use

Levonorgestrel-Releasing Intrauterine System Approved for 5-Year Use

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The expanded approval was supposed by safety and efficacy data from the Phase 3 ACCESS IUS trial (N = 1751) in women receiving Liletta. In the trial, Liletta demonstrated >99% efficacy in preventing pregnancy for up to 5 years in a broad patient population.

Safety and Efficacy of Dimethandrolone Undecanoate as Male Contraceptive Pill

Safety and Efficacy of Dimethandrolone Undecanoate as Male Contraceptive Pill

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Daily oral administration of dimethandrolone undecanoate for 28 days in healthy men is well tolerated and has properties consistent with an effective male contraceptive.

Weight Loss May Reduce Breast Cancer Risk in Postmenopausal Women

Weight Loss May Reduce Breast Cancer Risk in Postmenopausal Women

Postmenopausal women with weight loss have a reduced risk for breast cancer.

Mistaking Legal Recourse for Evidence-Based Medical Practices in Surrogacy

Mistaking Legal Recourse for Evidence-Based Medical Practices in Surrogacy

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Paying a surrogate to carry a fetus shoehorns a fourth, and fifth, party into the already tight therapeutic triangle formed by the biological mom, fetus, and physician.

New Testosterone Replacement Therapy Approved for At-Home Self-Administration

New Testosterone Replacement Therapy Approved for At-Home Self-Administration

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Xyosted carries a Boxed Warning regarding blood pressure increases that may potentially increase the risk for major adverse cardiovascular events.

Light Therapy Offers Nonpharmacologic Treatment for Perimenopausal Depression

Light Therapy Offers Nonpharmacologic Treatment for Perimenopausal Depression

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Light treatments successfully corrected abnormal timing of melatonin circadian rhythms in perimenopausal women with depression and improved mood and sleep within 2 weeks.

Medicaid Expansion Programs Improve Women's Access to Reproductive Services

Medicaid Expansion Programs Improve Women's Access to Reproductive Services

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One-third of the women enrolled in Michigan's Medicaid expansion program reported improved access to birth control and family planning services.

Gestational Diabetes Associated With Increased Risk for Postpartum Depression

Gestational Diabetes Associated With Increased Risk for Postpartum Depression

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These findings suggest an increased risk for postpartum depressive symptoms in mothers with gestational diabetes, independent of depressive symptomatology during pregnancy.

Physical Activity as a Lifestyle Factor Influencing Early Menopause

Physical Activity as a Lifestyle Factor Influencing Early Menopause

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Researchers concluded that physical activity was not associated with risk for early menopause.

Oral Contraceptives Associated With Ventricular Repolarization Alterations

Oral Contraceptives Associated With Ventricular Repolarization Alterations

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Healthy nonmenopausal women taking oral contraceptives exhibited biomarkers for drug-induced torsade de pointes.

Better Training Needed to Boost LGBTQ Patient Health Care

Better Training Needed to Boost LGBTQ Patient Health Care

High-quality health care needs to be provided to lesbian, gay, bisexual, transgender, and queer (LGBTQ) patients, and improved training is necessary to deliver that care.

Clinicians Should Learn to Engage With Transgender Patients

Clinicians Should Learn to Engage With Transgender Patients

Issues to consider include how to address patients, obtaining inclusive history, and unique clinical challenges.

Guidelines for Managing Perimenopausal Depression Now Available

Guidelines for Managing Perimenopausal Depression Now Available

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The 5 topics addressed by the 11-member expert panel include epidemiology, clinical presentation, therapeutic effects of antidepressants, effects of hormone therapy, and the effectiveness of other therapies (eg, psychotherapy, exercise, natural health products).

Cross-sex hormone therapy raises risk for vascular events in transgender women

Transgender women had higher rates of venous thrombotic events with cross-sex hormones.

Characteristics of Menstrual Cycle Associated With Early Natural Menopause

Characteristics of Menstrual Cycle Associated With Early Natural Menopause

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Investigators examined the relationship between menstrual cycle characteristics in adolescence and early adulthood and the risk for early natural menopause.

AMA Opposes Proposed Cuts, Gag Orders for Reproductive Health

AMA Opposes Proposed Cuts, Gag Orders for Reproductive Health

The American Medical Association strongly objects to the Trump administration's plan to withhold federal family planning funding from Planned Parenthood and other entities.

Young Cancer Survivors Have High Risk of Endocrine Diseases

Young Cancer Survivors Have High Risk of Endocrine Diseases

Adolescent and young adult cancer survivors have a 73 percent higher risk of endocrine diseases.

Ectopic Lipid Deposition and Insulin Resistance Higher in Postmenopausal Women

Ectopic Lipid Deposition and Insulin Resistance Higher in Postmenopausal Women

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The insulin sensitivity in post- and premenopausal women along with lipid deposition in the liver and skeletal muscle was examined.

Bayer Stops U.S. Sale of Essure Birth Control Implant

Bayer Stops U.S. Sale of Essure Birth Control Implant

Amid lawsuits and plummeting sales for its Essure birth control device, Bayer announced Friday that it would cease U.S. sales of the product by the end of 2018.

No Additional Benefits With Vaginal Estradiol Tablets, Moisturizers for Postmenopausal Vulvovaginal Symptoms

No Additional Benefits With Vaginal Estradiol Tablets, Moisturizers for Postmenopausal Vulvovaginal Symptoms

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Prescribed vaginal estradiol tablets and over-the-counter vaginal moisturizers may not be more effective than placebos for postmenopausal vulvovaginal symptoms.

Nutraceuticals Containing Equol May Be Effective for Postmenopausal Symptoms

Nutraceuticals Containing Equol May Be Effective for Postmenopausal Symptoms

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Equol-containing nutraceuticals may be beneficial for postmenopausal women with vaginal symptoms.

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