Type 2 Diabetes

Type 2 Diabetes Therapy Intensification: Part II: GLP-1 Agonist Adverse Effects and Fixed-Ratio Combinations

Type 2 Diabetes Therapy Intensification: Part II: GLP-1 Agonist Adverse Effects and Fixed-Ratio Combinations

When basal insulin no longer provides adequate glucose control in type 2 diabetes, a rapid-acting insulin or a glucagon-like peptide-1 receptor agonist may be used to intensify therapy.

Type 2 Diabetes Therapy Intensification: Part I: Insulin vs GLP-1 Agonists

Type 2 Diabetes Therapy Intensification: Part I: Insulin vs GLP-1 Agonists

When basal insulin no longer provides adequate glucose control in type 2 diabetes, a rapid-acting insulin or a glucagon-like peptide-1 receptor agonist may be used to intensify therapy.

Is Normal Basal Bone Metabolism Vitamin D-Dependent in Postmenopausal Women With T2D?

Is Normal Basal Bone Metabolism Vitamin D-Dependent in Postmenopausal Women With T2D?

Findings in postmenopausal women with T2DM; correlations prominent in those with higher 25(OH)D

Weekly GLP-1 Analog Improves Glycemic Control vs Glargine in T2D Inadequately Controlled on Metformin

Weekly GLP-1 Analog Improves Glycemic Control vs Glargine in T2D Inadequately Controlled on Metformin

By

A phase 3a trial evaluates whether the novel glucagon-like peptide-1 analog semaglutide substantially improved glycemic control compared with insulin glargine in patients with type 2 diabetes inadequately controlled with metformin.

Can Compression Socks Be Safely Used in Diabetics With Lower Extremity Edema?

Can Compression Socks Be Safely Used in Diabetics With Lower Extremity Edema?

By

A randomized controlled trial assessed whether mild lower extremity compression can be safely used in patients with diabetes and concurrent lower extremity edema.

Hypertension Family History May Accelerate Type 2 Diabetes Onset

Hypertension Family History May Accelerate Type 2 Diabetes Onset

By

A retrospective cohort study evaluated whether having a family history of hypertension accelerates onset of type 2 diabetes.

Urine Metabolomic Profiling: 5-HT Metabolism Contributes to DM Pathogenesis

Urine Metabolomic Profiling: 5-HT Metabolism Contributes to DM Pathogenesis

Derangements in serotonin metabolism and mitochondrial dysfunction may be inhibiting insulin secretion.

Daily Insulin Injection Vs Continuous Subcutaneous Infusion in Type 2 Diabetes

Daily Insulin Injection Vs Continuous Subcutaneous Infusion in Type 2 Diabetes

A broad range of patients with type 2 diabetes may benefit from continuous subcutaneous insulin infusion.

Inpatient Virtual Glucose Management Service Decreases Hyperglycemia, Hypoglycemia

Inpatient Virtual Glucose Management Service Decreases Hyperglycemia, Hypoglycemia

A study sought to determine if a virtual glucose management service can result in improved inpatient glycemic control.

Does Fiber Source Affect Plasma Glucose and Insulin in Type 2 Diabetes?

Does Fiber Source Affect Plasma Glucose and Insulin in Type 2 Diabetes?

By

Postprandial plasma glucose and insulin measurements were similar, regardless of fiber source.

Will Increasing Target A1C Goals Reduce Hypoglycemia Risk in Elderly Patients With T2D?

Will Increasing Target A1C Goals Reduce Hypoglycemia Risk in Elderly Patients With T2D?

By

No differences in hypoglycemia duration were reported among the hemoglobin A1c groups.

Hypovitaminosis D Associated With High 24-Hour Ambulatory BP in Type 2 Diabetes

Hypovitaminosis D Associated With High 24-Hour Ambulatory BP in Type 2 Diabetes

By

Researchers examined 24-hour and ambulatory blood pressure to determine the relationship between hypertension and low levels of vitamin D.

Circadian Preference Linked to Depression Rates in Type 2 Diabetes

Circadian Preference Linked to Depression Rates in Type 2 Diabetes

By

Patients with type 2 diabetes who prefer staying up late at night show more symptoms of depression than those who wake up and sleep earlier.

Elevated Pancreatic Polypeptide May Predict Coronary Artery Disease in T2DM

Elevated Pancreatic Polypeptide May Predict Coronary Artery Disease in T2DM

By

Pancreatic polypeptide significantly correlated with Framingham 10-year risk for coronary artery disease.

Insulin Pump Therapy Improves QoL for Adolescents With T2DM

Insulin Pump Therapy Improves QoL for Adolescents With T2DM

By

At the end of a 3-month period, adolescents with type 2 diabetes experienced decreased HbA1c levels after using insulin pump therapy.

Empagliflozin Use Supported in Patients With DM Post-Cardiac Transplantation

Empagliflozin Use Supported in Patients With DM Post-Cardiac Transplantation

By

Both mean body weight and body mass index were reduced with empagliflozin in patients with diabetes following cardiac transplant.

Systemic Anti-inflammatory Effects of Linagliptin in Type 2 Diabetes

Systemic Anti-inflammatory Effects of Linagliptin in Type 2 Diabetes

By

Linagliptin decreased HbA1c, as well as reactive oxygen species generation and plasma lipid peroxide levels.

Diabetes Incidence Rates Increase With Higher Outdoor Temperature in US

Diabetes Incidence Rates Increase With Higher Outdoor Temperature in US

By

The age-adjusted diabetes incidence rates increased per 1°C increase in temperature.

Admission Hyperglycemia Associated With Poststroke Infection, Worse Outcomes

Admission Hyperglycemia Associated With Poststroke Infection, Worse Outcomes

By

Data from 2550 patients indicated a possible relationship between admission hyperglycemia and poststroke infection.

Should Trabecular Bone Score Be Used to Assess Bone Quality in Type 2 Diabetes?

Should Trabecular Bone Score Be Used to Assess Bone Quality in Type 2 Diabetes?

By

The trabecular bone score may provides an acute, albeit indirect, measurement of bone quality in patients with type 2 diabetes.

Diabetic Retinopathy Screening Lacking Among Pediatric Patients

Diabetic Retinopathy Screening Lacking Among Pediatric Patients

Black and Latino youth were less likely to undergo an eye examination for diabetic retinopathy within 6 years of their diagnosis.

Higher Complications, Comorbidities in Youth With Type 2 Versus Type 1 Diabetes

Higher Complications, Comorbidities in Youth With Type 2 Versus Type 1 Diabetes

By

The prevalence of complications associated with type 1 and type 2 diabetes diagnosed during childhood and adolescence was compared in a multicenter, observational study.

Do Higher Temperatures Increase Diabetes Incidence?

Do Higher Temperatures Increase Diabetes Incidence?

Age-adjusted diabetes incidence increased for every 1 degree celcius temperature increase.

Factors Associated With Lack of Diabetes Disease Awareness Identified

Factors Associated With Lack of Diabetes Disease Awareness Identified

A study found approximately one-third of people with diabetes were undiagnosed or unaware of the diagnosis.

Mortality In Type 2 Diabetes Increased With Severe Hypoglycemia Episode

Mortality In Type 2 Diabetes Increased With Severe Hypoglycemia Episode

Researchers identified hypoglycemia as an "under-recognized" risk factor for death and CVD in people with type 2 diabetes.

Brief Intensive Lifestyle and Drug Therapy Beneficial in Type 2 Diabetes

Brief Intensive Lifestyle and Drug Therapy Beneficial in Type 2 Diabetes

Participants who received either an 8- or 16-week course of intensive lifestyle and drug therapy achieved hemoglobin A1c criteria for complete or partial diabetes remission.

Differential Adverse Renal Effects With Dapagliflozin, Empagliflozin in Type 2 Diabetes

Differential Adverse Renal Effects With Dapagliflozin, Empagliflozin in Type 2 Diabetes

By

A comprehensive systematic review analyzes whether specific sodium-glucose cotransporter 2 inhibitors were more likely to be associated with adverse renal events in patients with type 2 diabetes.

Update: ADA Standards of Medical Care in Diabetes Emphasize Metformin Therapy

Update: ADA Standards of Medical Care in Diabetes Emphasize Metformin Therapy

An update to the ADA's 2017 Standards of Medical Care in Diabetes indicates that, barring contraindication, patients with type 2 diabetes should undergo metformin therapy as first-line treatment.

A Clinician's Plea for More Pragmatic Clinical Trials in Diabetes

A Clinician's Plea for More Pragmatic Clinical Trials in Diabetes

By

Studies designed to address real-world challenges can potentially lead to both better-informed clinical decision making and improved outcomes.

Ethnicity-Based Variations in Type 2 Diabetes Risk

Ethnicity-Based Variations in Type 2 Diabetes Risk

Study participants of South Asian ethnicity were more more likely to develop type 2 diabetes with a BMI between 18 and 30 kg/m2.

Sign Up for Free e-Newsletters