Type 2 Diabetes

Direct-Acting Antiviral Therapy Reduced Risk for Incident T2D in Patients With Hepatitis C Infection

Direct-Acting Antiviral Therapy Reduced Risk for Incident T2D in Patients With Hepatitis C Infection

The study compared US administrative claims data of HCV patients with ≥12 weeks of dispensed DAA therapy (N = 17,848) to untreated HCV patients with follow-up data (N = 108,350).

Dapagliflozin Lowers Heart Failure Hospitalization Rates in High-Risk Patients With Diabetes

Dapagliflozin Lowers Heart Failure Hospitalization Rates in High-Risk Patients With Diabetes

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Dapagliflozin was not associated with either a higher or lower rate of MACE compared with placebo in patients with type 2 diabetes who had or were at risk for atherosclerotic cardiovascular disease.

High Circulating Prolactin Concentrations May Lower Risk for Type 2 Diabetes

High Circulating Prolactin Concentrations May Lower Risk for Type 2 Diabetes

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High circulating total prolactin concentrations may be linked with a lower risk for type 2 diabetes in women.

ADA Issues Position Statement on Comprehensive Care for Pediatric T2D

ADA Issues Position Statement on Comprehensive Care for Pediatric T2D

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The American Diabetes Association issued a position statement outlining the recognition, management, and prevention of T2D in the pediatric population.

Peer Support Reduces Hospitalizations in People With Diabetes and Depression

Peer Support Reduces Hospitalizations in People With Diabetes and Depression

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Patients with diabetes and depressive symptoms who received community-based peer support for diabetes management reported less frequent acute care visits and hospitalizations than patients with diabetes without depressive symptoms.

Empagliflozin Effectively Reduces Risk for Heart Failure Hospitalization in T2D

Empagliflozin Effectively Reduces Risk for Heart Failure Hospitalization in T2D

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Approximately 50% of deaths in people with type 2 diabetes worldwide, and approximately two-thirds of deaths in people with type 2 diabetes in the US are caused by cardiovascular disease.

Pathogenesis of Postprandial Hypoglycemia After Roux-en-Y Gastric Bypass in T2D

Pathogenesis of Postprandial Hypoglycemia After Roux-en-Y Gastric Bypass in T2D

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Postprandial hypoglycemia may occur after Roux-en-Y gastric bypass in patients with type 2 diabetes, independent from diabetes remission.

Acute and Persistent Prothrombic Effects Observed With Antecedent Hypoglycemia in T2D

Acute and Persistent Prothrombic Effects Observed With Antecedent Hypoglycemia in T2D

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Hypoglycemia was associated with early and late prothrombotic changes in the fibrin network in individuals with type 2 diabetes.

Extra-Glycemic Effects May Explain Different CV Outcomes With Dapagliflozin, Vildagliptin

Extra-Glycemic Effects May Explain Different CV Outcomes With Dapagliflozin, Vildagliptin

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Dapaglifozin and vildagliptin impact cardio-metabolic processes differently.

Patients With T2D and Sickle-Cell Trait at Higher Risk for Complications

Patients With T2D and Sickle-Cell Trait at Higher Risk for Complications

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Diabetic complications were more prevalent in patients with both sickle-cell trait and T2D than in patients with T2D alone.

AHA, ADA Announce Joint Education Initiative to Reduce CVD Deaths in T2D

AHA, ADA Announce Joint Education Initiative to Reduce CVD Deaths in T2D

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The ADA and the AHA launch a long-term awareness and education initiative for the prevention of deaths due to cardiovascular complications in patients with T2D.

Risk for T2D Increases Following Total or Partial Colectomy

Risk for T2D Increases Following Total or Partial Colectomy

Patients who have the entire or left side of the colon removed show increased risk for developing type 2 diabetes in the 18 years following surgery.

Type 2 Diabetes May Have Adverse Effect on Parkinson Disease Symptoms, Outcomes

Type 2 Diabetes May Have Adverse Effect on Parkinson Disease Symptoms, Outcomes

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Patients with both Parkinson disease and type 2 diabetes were more likely to have cardiovascular comorbidities than those with only Parkinson disease.

Plant-Based Diets Beneficial for Adults With Type 2 Diabetes

Plant-Based Diets Beneficial for Adults With Type 2 Diabetes

For adults with type 2 diabetes, plant-based diets can improve psychological health, quality of life, hemoglobin A1c levels, and weight.

Lipidome Profiles Stratify Risk for Type 2 Diabetes

Lipidome Profiles Stratify Risk for Type 2 Diabetes

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Early detection of lipidome characteristics could help identify the early onset of type 2 diabetes.

Diabetes Education Week 2018: Patient Resources for Your Practice

Diabetes Education Week 2018: Patient Resources for Your Practice

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In recognition of National Diabetes Education Week, Endocrinology Advisor compiled a list of resources to assist clinicians when educating patients with diabetes about their condition.

Intensive BP, Lipid Control in T2D May Increase Risk for Adverse Kidney Events

Intensive BP, Lipid Control in T2D May Increase Risk for Adverse Kidney Events

Intensive BP control and fenofibrate use in patients with T2D who are at high risk for CVD may increase the risk for adverse kidney events.

Exposure to Ready-to-Eat Food Outlets Associated With Risk for Type 2 Diabetes

Exposure to Ready-to-Eat Food Outlets Associated With Risk for Type 2 Diabetes

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Access to ready-to-eat outlets that sell food for instant consumption is associated with greater risk for type 2 diabetes.

Another Antihypertensive Recalled Due to Potentially Carcinogenic Impurity

Another Antihypertensive Recalled Due to Potentially Carcinogenic Impurity

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The impurity was identified following laboratory testing conducted by the Food and Drug Administration (FDA); this is the first non-valsartan product that the Agency has found to contain NDEA.

Bardoxolone Methyl Leads to Weight Loss in T2D with Concurrent Chronic Kidney Disease

Bardoxolone Methyl Leads to Weight Loss in T2D with Concurrent Chronic Kidney Disease

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Treatment with bardoxolone methyl resulted in significant weight loss and showed no evidence of muscle wasting in patients with type 2 diabetes and stage IV chronic kidney disease.

Hyperglycemia, Obesity, Hypertriglyceridemia Negatively Related to CAN in T2D

Hyperglycemia, Obesity, Hypertriglyceridemia Negatively Related to CAN in T2D

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Hyperglycemia, obesity, and hypertriglyceridemia in type 2 diabetes are negatively related to indices of cardiovascular autonomic neuropathy.

Canagliflozin Approved to Reduce Risk for Cardiovascular Events in T2D

Canagliflozin Approved to Reduce Risk for Cardiovascular Events in T2D

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The effect of Invokana on CV risk was evaluated in the CANVAS (CANagliflozin cardioVascular Assessment Study) Program in >10,000 adults with T2D who had established CV disease or were at risk for CV disease with ≥2 risk factors.

Early Natural Menopause Linked to Life Expectancy, Years With T2D

Early Natural Menopause Linked to Life Expectancy, Years With T2D

Compared with women who experience normal or late menopause, women who experience early natural menopause have a shorter life expectancy and spend fewer years without type 2 diabetes.

Type 2 Diabetes an Independent Risk Factor for Coronary Artery Disease

Type 2 Diabetes an Independent Risk Factor for Coronary Artery Disease

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Type 2 diabetes is an independent risk factor for sudden cardiac arrest and death in patients with coronary artery disease with preserved ejection fraction.

Dual GIP, GLP-1 Receptor Agonist Effective for Weight Loss, Glucose Control in T2D

Dual GIP, GLP-1 Receptor Agonist Effective for Weight Loss, Glucose Control in T2D

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LY3298176, a dual GIP and GLP-1 receptor agonist, showed significantly better efficacy than dulaglutide with regard to glucose control and weight loss in type 2 diabetes.

Gastric Banding vs Metformin for Improved Insulin Sensitivity in Mild T2D

Gastric Banding vs Metformin for Improved Insulin Sensitivity in Mild T2D

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Gastric banding and metformin resulted in similar improvements in insulin sensitivity in moderately obese adults with impaired glucose tolerance or mild T2D over a 2-year period.

Biomarkers of Dairy Fat Consumption Inversely Associated With Type 2 Diabetes Risk

Biomarkers of Dairy Fat Consumption Inversely Associated With Type 2 Diabetes Risk

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Researchers found that higher levels of fatty acid biomarkers 15:0, 17:0, and trans-16:1n7 were inversely associated with risk for T2D.

Glucose Dysregulation Begins Years Before Diabetes Diagnosis

Glucose Dysregulation Begins Years Before Diabetes Diagnosis

Individuals who develop diabetes or prediabetes have elevated fasting plasma glucose (FPG) at least 10 years before diagnosis.

Incretin-Based Therapies Not Associated With New-Onset Depression, Self-Harm in T2D

Incretin-Based Therapies Not Associated With New-Onset Depression, Self-Harm in T2D

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There was not a clinically relevant association between DPP-4 inhibitors or GLP-1 receptor agonists and depression or self-harm in type 2 diabetes.

Severity of Metabolic Syndrome Indicates Risk for T2D, CVD in Prediabetes Treatment

Severity of Metabolic Syndrome Indicates Risk for T2D, CVD in Prediabetes Treatment

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Researchers analyzed how improvements in metabolic syndrome may impact the risk of developing type 2 diabetes and cardiovascular disease in patients with prediabetes.

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