Type 2 Diabetes

Healthy Lifestyle With Diabetes Cuts Cardiovascular Risk

Healthy Lifestyle With Diabetes Cuts Cardiovascular Risk

Greater adherence to an overall healthy lifestyle is associated with a substantially lower risk for cardiovascular disease.

DPP-4 Inhibitors and Incidence of Rheumatoid Arthritis in Type 2 Diabetes

DPP-4 Inhibitors and Incidence of Rheumatoid Arthritis in Type 2 Diabetes

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Investigators sought to determine whether the use of dipeptidyl peptidase-4 inhibitors is associated with the incidence of rheumatoid arthritis.

Sitagliptin May Improve Glycemic Control Better Than Dapagliflozin in T2D With Mild Renal Insufficiency

Sitagliptin May Improve Glycemic Control Better Than Dapagliflozin in T2D With Mild Renal Insufficiency

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The safety and efficacy of sitagliptin vs dapagliflozin in patients with type 2 diabetes and renal insufficiency was examined.

Intermittent vs Continuous Energy-Restricted Diet: Effects on Glycemic Control and Weight Loss T2D

Intermittent vs Continuous Energy-Restricted Diet: Effects on Glycemic Control and Weight Loss T2D

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Intermittent energy restriction diet may be an effective alternative diet strategy for reducing HbA1c in patients with type 2 diabetes.

Second-Line Therapies Show Benefit Over Metformin Monotherapy in T2D

Second-Line Therapies Show Benefit Over Metformin Monotherapy in T2D

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Investigators assessed the effect of second-line therapies on weight, HbA1c, and treatment persistence over 18 months in patients who had received metformin monotherapy.

Dapagliflozin Plus Omega-3 Carboxylic Acids for Non-Alcoholic Fatty Liver Disease in T2D

Dapagliflozin Plus Omega-3 Carboxylic Acids for Non-Alcoholic Fatty Liver Disease in T2D

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Combination treatment with dapagliflozin plus omega-3 carboxylic acids may reduce fat content in nonalcoholic fatty liver disease.

One in Four Older Adults With Diabetes Uses Alternative Meds

One in Four Older Adults With Diabetes Uses Alternative Meds

More than 25 percent of older U.S. adults with diabetes use some type of complementary and alternative medicine.

HbA1c-Corrected FRAX Score May Better Predict Fracture Risk in Type 2 Diabetes

HbA1c-Corrected FRAX Score May Better Predict Fracture Risk in Type 2 Diabetes

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A corrected HbA1C factor may improve the ability to predict the risk for fracture by the FRAX algorithm in T2D.

Estimating Risk Factors and Trajectories for Diabetic Polyneuropathy

Estimating Risk Factors and Trajectories for Diabetic Polyneuropathy

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Investigators examined cardiometabolic risk factor trajectories in patients diagnosed with type 2 diabetes over the course of 13 years preceding diabetic polyneuropathy.

G6 CGM System Offers Improved Accuracy in Youth and Adults With Diabetes

G6 CGM System Offers Improved Accuracy in Youth and Adults With Diabetes

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Investigators evaluate the performance of the G6 factory-calibrated continuous glucose monitoring system over 10 days.

Hepatic Markers Linked to Early Predictors of Type 2 Diabetes Risk in Women

Hepatic Markers Linked to Early Predictors of Type 2 Diabetes Risk in Women

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Circulating hepatic markers may predict the risk for diabetes in women.

Diabetes Diagnosis May Impact Health Behaviors of Family

Diabetes Diagnosis May Impact Health Behaviors of Family

Partners of people with newly diagnosed diabetes have small but significant differences in health-related behavioral changes compared with partners of people without diabetes.

Risk for Heart Failure Up in ALVSD Patients With Diabetes

Risk for Heart Failure Up in ALVSD Patients With Diabetes

For patients with asymptomatic left ventricular systolic dysfunction (ALVSD), those with diabetes have increased risk of heart failure development and hospitalization.

Detecting and Treating Depression in Diabetes

Detecting and Treating Depression in Diabetes

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Comorbid depression, when not well controlled, can affect one's ability to self-manage diabetes. There can be loss of interest in making proper lifestyle choices, monitoring glucose levels, and taking one's medicines.

Hippocampal Calcification Associated With Aging, Diabetes, and Smoking

Hippocampal Calcification Associated With Aging, Diabetes, and Smoking

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Investigators aim to identify risk factors for hippocampal calcifications and to investigate the relationship between hippocampal calcifications and cognitive function.

Second-Line Sulfonylurea Therapy Linked to Cardiovascular Events in Type 2 Diabetes

Second-Line Sulfonylurea Therapy Linked to Cardiovascular Events in Type 2 Diabetes

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Researchers assessed whether adding or switching to sulfonylureas is linked to increased risk for myocardial infarction, ischemic stroke, hypoglycemia, and all-cause mortality.

Risk for Diabetic Retinopathy With Incretin-Based Therapies

Risk for Diabetic Retinopathy With Incretin-Based Therapies

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Investigators examined whether incretin-based therapies increase the risk for diabetic retinopathy compared with other antihyperglycemic agents.

Diabetic Retinopathy May Be Independent Risk Factor for Parkinson Disease

Diabetic Retinopathy May Be Independent Risk Factor for Parkinson Disease

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Results support that there is a relationship between diabetic retinopathy and Parkinson disease.

Characteristics of Severe Hypoglycemia Identified in T2DM

Characteristics of Severe Hypoglycemia Identified in T2DM

For patients with type 2 diabetes, characteristics of those with severe hypoglycemia include having a prior diagnosis of non-severe hypoglycemia and hemoglobin A1c (HbA1c) <6 percent.

PM<sub>2.5</sub> Contributes to Burden of Diabetes Mellitus Globally

PM2.5 Contributes to Burden of Diabetes Mellitus Globally

Particulate matter (PM) with a diameter of less than 2.5 micrograms per cubic meter of air (PM2.5) makes a substantial contribution to the burden of diabetes.

Basal Insulin Analogs for Type 2 Diabetes Are Similar in Efficacy

Basal Insulin Analogs for Type 2 Diabetes Are Similar in Efficacy

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A meta-analysis was conducted to examine the safety and efficacy of basal insulin analogs for type 2 diabetes.

Trulicity Labeling Updated to Include Data on T2D Patients With CKD

Trulicity Labeling Updated to Include Data on T2D Patients With CKD

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In the AWARD-7 trial, patients who received Trulicity 0.75mg or 1.5mg in combination with mealtime insulin lispro achieved similar glycemic control with weight loss vs patients who received traditional basal-bolus insulin.

New Data Support Long-Term Cardiovascular Safety of Linagliptin in T2D

New Data Support Long-Term Cardiovascular Safety of Linagliptin in T2D

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Results showed the overall safety profile of linagliptin in study patients, including adults with kidney disease, was consistent with previous data.

Severe Hypoglycemia in Type 2 Diabetes Linked to Poor Cognitive Outcomes

Severe Hypoglycemia in Type 2 Diabetes Linked to Poor Cognitive Outcomes

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Adjustment of glucose-lowering medications in patients who are at high-risk for severe hypoglycemia may be beneficial to prevent mild cognitive impairment.

Canagliflozin Trial for T2D With CKD Stopped Early Due to Positive Results

Canagliflozin Trial for T2D With CKD Stopped Early Due to Positive Results

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A clinical trial assessing canagliflozin (Invokana; Janssen) as an addition to standard-of-care in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D) has been stopped early after meeting its pre-specified efficacy criteria.

Circadian System, Misalignment Have Distinct Impact on Insulin

Circadian System, Misalignment Have Distinct Impact on Insulin

The endogenous circadian system, behavioral cycle, and circadian misalignment have distinct effects on insulin sensitivity and β-cell function.

Travel Costs Are Considerable Part of T2DM Follow-Up Costs

Travel Costs Are Considerable Part of T2DM Follow-Up Costs

For patients with type 2 diabetes mellitus (T2DM), travel costs relating to hemoglobin A1c (HbA1c) screening constitute a substantial cost item, and self-monitoring can reduce costs.

Favorable Outcomes With Second-Generation Insulin Analogs in Type 2 Diabetes

Favorable Outcomes With Second-Generation Insulin Analogs in Type 2 Diabetes

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A retrospective, observational study was conducted to assess outcomes in patients with type 2 diabetes treated with second-generation basal insulin analogs.

β-Cell Function in Youth With Impaired Glucose Tolerance, T2D

β-Cell Function in Youth With Impaired Glucose Tolerance, T2D

Investigators examined whether β-cell function can be improved or preserved with antihyperglycemic agents in young patients.

Link Between Oral Diabetes Medications and Bullous Pemphigoid

Link Between Oral Diabetes Medications and Bullous Pemphigoid

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Finnish investigators evaluated the link between diabetes medications other than DPP-4 inhibitors and the risk for BP.

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