Intraplaque Hemorrhage Prevalent in Type 2 Diabetes

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Intraplaque hemorrhage was seen in nearly one quarter of patients with type 2 diabetes.
Intraplaque hemorrhage was seen in nearly one quarter of patients with type 2 diabetes.

(HealthDay News) — Intraplaque hemorrhage is prevalent in 23.3% of asymptomatic patients with type 2 diabetes, according to a study presented at the annual meeting of the Radiological Society of North America in Chicago.

Tishan Maraj, MBBS, from the Sunnybrook Research Institute in Toronto, and colleagues recruited 159 asymptomatic patients with type 2 diabetes who underwent baseline 3-dimensional magnetic resonance imaging for visualization of IPH. VesselMASS software was used to determine carotid artery vessel wall (VW) volumes and IPH volumes for a standard 32 mm segment centered at each carotid bifurcation.

The researchers found that the prevalence of IPH was 23.3% with IPH seen in both carotid arteries of 5 patients. VW volume was significantly different for IPH-positive carotid arteries vs IPH-negative arteries; after adjustment for disease duration, smoking, blood pressure, and medications, the correlation was independent from other factors that affected VW volume (age, sex, and BMI).

"It was surprising that so many diabetic patients had this feature," Maraj said in a statement. "We already knew that people with diabetes face 3 to 5 times the risk of stroke, so perhaps IPH is an early indicator of stroke risk that should be followed up."

References

  1. Maraj T, Moody AR, Singh N, et al. dvanced Atherosclerotic Disease with Intraplaque Hemorrhage is Present in Non-Stenotic Carotid Arteries of Diabetic Patients. Presented at the Radiological Society of North America Annual Meeting; November 29-December 4, 2015; Chicago, IL.
  2. 3-D MRI Shows Early Signs of Stroke Risk in Diabetic Patients [news release]. RSNA Media; November 24, 2015. https://www2.rsna.org/timssnet/media/pressreleases/14_pr_target.cfm?ID=1839. Accessed November 30, 2015.
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