Chronic Hepatitis B Prevalence Higher in Type 2 Diabetes

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Patients with type 2 diabetes have higher prevalence of chronic hepatitis B infection.
Patients with type 2 diabetes have higher prevalence of chronic hepatitis B infection.

HealthDay News -- Patients with type 2 diabetes have higher prevalence of chronic hepatitis B virus infection, according to a study published in the Journal of Diabetes Investigation.

Jun Lu, PhD, from the Shanghai Jiao Tong University Affiliated Sixth People's Hospital, and colleagues investigated the prevalence of chronic hepatitis B virus status in different diabetes subtypes among a Chinese population. Participants included 381 cases with adult-onset autoimmune diabetes, 1365 patients with type 2 diabetes, and 1365 controls without diabetes.

The researchers found that patients with type 2 diabetes had higher prevalence of chronic hepatitis B than the controls in the overall population (13.5% vs 10.0%; P =.004) and among patients with normal hepatic function (13.3% vs 8.8%; P =.002). However, chronic hepatitis B status was not different between patients with adult-onset autoimmune diabetes and the controls. The odds ratio of chronic hepatitis B increased about 1.5-fold in patients with type 2 diabetes, compared with the control group, even after adjustment for age, gender, and body mass index, regardless of hepatic function.

"Further research is required to ascertain whether [chronic hepatitis B] status increases the risk of developing type 2 diabetes, or whether type 2 diabetes, but not adult-onset autoimmune diabetes, increases the risk of chronic hepatitis B," the researcher wrote.

Reference

  1. Lu J, Hou X, Tu H, et al. Hepatitis B Virus Infection Status is more prevalent in patients with type 2 diabetes [published online December 8, 2016]. J Diabetes Investig. doi:10.1111/jdi.12609.
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