Type 2 Diabetes Archive
For patients with type 2 diabetes undergoing non-cardiac surgery, premedication with liraglutide is associated with reduced median plasma glucose 1 hour postoperatively.
Antidiabetic agents for the treatment of diabetes including maintenance and max doses.
A smart exendin-4 delivery device is a promising therapeutic option for type 2 diabetes that can provide safe, long-term, and on-demand Ex4 therapy.
The FDA has granted marketing clearance of the first shock wave device intended for use in the treatment of chronic, full-thickness diabetic foot ulcers.
Researchers assessed the effect of both type 2 diabetes and baseline cardiovascular disease risk on the treatment effect of intensive blood pressure lowering based on data and pooled analysis from 14,094 patients.
Risk of cardiovascular events in people with type 2 diabetes and subgroups of coronary artery disease was examined.
Steglatro is indicated as adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus, and Steglujan is indicated as adjunct when treatment with both ertugliflozin and sitagliptin are appropriate.
While there is increasing positive data for the utilization of ranolazine, a majority of the data did not come from large randomized controlled trials that looked at metabolic parameters as their primary end point.
Corticosteroids should be used with caution in patients with diabetes and mitigating factors should be considered.
Network meta-analysis provided some information on differences between DPP-4 inhibitors, traditional anti-diabetes agents, and placebo in bone fracture.
Patients from 3 sites participated in a trial examining the noninferiority of telemedicine vs standard outpatient care for diabetic foot ulcer follow-up treatment.
Urinary albumin-to-creatinine ratio can be independently associated with various adverse CV outcomes.
Study sought to determine the optimal dosing of linagliptin for the treatment of children with type 2 diabetes.
Patients with diabetes report worse quality of life with more intensified treatment, demonstrating the importance of measuring quality of life outcomes when evaluating diabetes treatments.
Investigators sought to examine whether individuals with prediabetes, based on A1c and fasting plasma glucose levels, would have a diagnosis of diabetes when using a 2-hour plasma glucose test.
In patients with diabetes, coronary artery bypass grafting may be the preferred method of revascularization, with lower rates of major adverse cardiac or cerebrovascular events.
No convincing evidence that the interplay of dietary and genetic factors related to body iron status associates with the risk of type 2 diabetes above the level expected.
A randomized controlled trial evaluated whether treatment intensification with biphasic insulin aspart 30 improved glycemic control in patients with type 2 diabetes.
There were no significant differences in coronary disease-specific health status or dyspnea benefits of chronic total occlusion PCI in patients with and without diabetes.
Findings from a new study suggest that episodes of severe hypoglycemia in patients with diabetes are associated with high rates of subsequent cardiovascular events.
A study sought to clarify whether total physical activity during the day is equally as important as achieving high levels of intensity associated with moderate-to-vigorous physical activity.
A prospective cohort study was conducted to determine if 1 hour vs 2 hour blood glucose levels were better for predicting the development of type 2 diabetes.
Patients with diabetes taking saxagliptin, sitagliptin, second-generation sulfonylureas, pioglitazone, and long-acting insulin were assessed for the risk of acute myocardial infarction.
A strong association was found in study between poor survival in elderly patients with type 2 diabetes and cardiovascular complications, especially heart failure.
Drug approval was granted through an abbreviated approval pathway, based on Humalog clinical data.
Investigators believe that type 2 diabetes risk assessment would be optimal with fasting glucose and HbA1c levels.
A remotely connected diabetes management system increased patent satisfaction and improved glycemic control in patients with insulin-treated diabetes.
Bone mineral density was evaluated annually of the lumbar spine and femoral neck.
Investigators discuss an added benefit of using DPP4 inhibitors would be a lower incidence of hypoglycemia.
Semaglutide, a once-weekly GLP-1 receptor agonist, demonstrated clinically significant reductions in HbA1c among adults with type 2 diabetes.
The Food and Drug Administration has posted a recall notification for 2 lots of Riomet 500mg/5mL due to the possibility that the liquid may be contaminated with Scopulariopsis brevicaulis.
Despite the well‐recognized correlation between weight gain and cardiovascular (CV) disease, there is little direct evidence relating to the impact of insulin‐induced weight gain on CV outcomes.
Interventions targeting sleep duration could have a significant impact on health outcomes when considering the importance of diabetes for a wide range of diseases.
Interim analysis of the follow-up Veterans Affairs Diabetes Trial study shows that intensive glycemic control for a median of 5.6 years may have a modest beneficial effect on delaying the progression of renal disease.
Once-weekly administration of extended-release exenatide in patients with T2D at a wide range of cardiovascular risk appeared not to cause an increase in their overall cardiovascular risk.
For patients with psoriasis, an increase in body surface area affected by the disease may be associated with a greater risk of type 2 diabetes.
Empagliflozin lowered the risk of cardiovascular death vs placebo when added to standard of care in adults with both type 2 diabetes and peripheral artery disease.
The rise of brain glucose levels is blunted during hyperglycemia in adults with obesity and type 2 diabetes mellitus.
A study of the once-weekly investigational dipeptidyl peptidase-4 omarigliptin reported a clinically meaningful reduction in glycated hemoglobin that was maintained throughout the study.
The high prevalence of T2D in African American women could explain previously identified racial disparities in breast cancer incidence.
Levels of high sensitivity C-reactive protein may help risk stratify those patients with T2D and recent acute coronary syndrome at further risk of recurrent cardiovascular events.
The association between statin use and diabetes risk in a cohort of overweight and obese patients was examined.
Researchers assessed whether long-term use of long-acting insulin analogs, compared with the use of neutral protamine Hagedorn insulin, is associated with an increased risk of breast cancer in women with T2D.
Albuminuria may be an effective prognostic indicator of adverse outcomes risk in patients with diabetes.
Acarbose, an α-glucosidase inhibitor, decreased the incidence of diabetes in a population with impaired glucose tolerance who were at low risk of cardiovascular events.
Metformin is linked to a lower dementia risk compared to sulfonylureas among veterans with type 2 diabetes.
Researchers evaluated a meta-analysis of randomized controlled trials and an analysis of the FDA AE Reporting System to determine whether combination DPP4i/SGLT2i medication lowers risk of GUTI.
All dosages of oral semaglutide reduced mean HbA1c level significantly more than placebo by week 26.
People with type 2 diabetes and NOCS-NSTEMI who used incretin had a better prognosis than non-incretin users.
A study confirms whether severe hypoglycemia increases risk for all-cause mortality in patients with type 2 diabetes.
Study revealed heterogeneity in plasma glucose response to oral glucose intake beyond the established glucose criteria based on fasting plasma glucose and 2 h post-load plasma glucose levels.
Professional continuous glucose monitoring can significantly reduce the economic burden of type 2 diabetes.
Undiagnosed diabetes is a relatively small fraction of the total diabetes population when a confirmatory definition is used.
Second-line treatments are often initiated without first using first-line therapies.
Studies have not previously examined long-term risks or mortality after aortic aneurysm or dissection in people with type 2 diabetes.
Higher magnesium intake was linked to a 15% lower risk for type 2 diabetes.
Retinal sensitivity, assessed by microperimetry, is related to brain neurodegeneration in T2D.
Diabetes following pancreatic disease often requires higher use of insulin and worse glycemic control.
Study highlights the need to examine the safety of new glucose-lowering treatments specifically in patients with diabetes and heart failure and reduced ejection fraction.
People with T2D experienced greater HbA1c reductions with the addition of a DPP4 inhibitor vs placebo.
A recent population-based study is the first to examine the risk of type 2 diabetes associated with the use of antidepressant medication in children and adolescents.
Based on glycemic control and treatment method, type 2 diabetes in the heart failure population can be indicative of various risk associations.
Heart failure prevention may be an opportunity to reduce the risk of death in specific cardiovascular subcategories.
The new formulation of Bydureon BCise allows for once-weekly administration with an autoinjector pen.
The efficacy of liraglutide therapy was examined in metformin-treated subjects with obesity.
Greater prognostic advantages were associated with high-dose beta blockers in chronic heart failure with diabetes.
Overall reduction in HbA1c was higher in people with T2D vs those with T1D.
HbA1c, fasting plasma glucose, and body weight were significantly reduced in all patients taking tofogliflozin.
With a little communication, children with diabetes can still enjoy Halloween festivities.
Twenty-five percent of people with type 2 diabetes and 12% of people with type 1 diabetes had depression.
The update provides guidance within 7 areas of type 2 diabetes management, including patient centered care and individualized treatment plans.
However, sulfonylurea plus insulin was linked to more hypglycemic events than insulin alone.
Referral to a commercial weight management program, such as Weight Watchers, can be effective in preventing diabetes.
Researchers have identified lasting benefits for patients with severe obesity who undergo Roux-en-Y gastric bypass surgery.
For medicare recipients it is more common to be overtreated than undertreated for diabetes.
One clinic shares results after replacing magazines with tablets allowing patients to examine their risk of developing diabetes.
Liraglutide plus usual care resulted in lower rates of diabetic kidney disease-specific outcomes in type 2 diabetes.
Researchers identified several novel plasma biomarkers that can be used to predict rapid decline in renal function in T2D, independent of traditional risk factors.
Clinicians should identify barriers to patient participation in diabetes self-management classes.
Results suggest that medication adherence is associated with reduced risk of all-cause mortality in T2D.
BMI measurement alone can also be used to determine associations between childhood and adulthood conditions.
Validation-tool identified "high risk" patients were more likely to report hypoglycemia episodes and subsequent emergence department use.
The efficacy of diagnosing diabetes or prediabetes using fasting plasma glucose vs traditional HbA1c test was examined.
The study included over 45,000 children using second-generation antipsychotic medications between 2009 and 2013.
Patients with type 2 diabetes and those with diabetes secondary to chronic pancreatitis have similarly impaired α-cell responses to oral glucose ingestion and hypoglycemia.
New monitoring system involves the placement of a small sensor wire beneath the skin surface to continuously monitor glucose levels.
Patients with MACE showed a greater extent of more severe coronary artery disease.
Researchers examined how adipocyte size reduction and fatty acid metabolism contribute to remission in type 2 diabetes following bariatric surgery.
Diacerein was well-tolerated among trial participants, and may be an acceptable adjunct treatment in type 2 diabetes.
Three hundred physically inactive or sedentary patients received either theoretical and practical counseling once-yearly for 3 years, or standard care.
Researchers identified strong inverse graded relationships between children's sleep duration, adiposity, and the presence of diabetes risk markers.
A retrospective analysis examined outcomes in patients with type 2 diabetes treated with SGLT2 vs DPP4 inhibitors.
Weight loss in people with type 2 diabetes is associated with extended life expectancy.
Women with atrial fibrillation and diabetes had a higher risk for mortality and cardiovascular complications compared with men.
Researchers examined the efficacy of cognitive behavioral group therapy on preventing weight regain or modifying cardiovascular risk factors and psychological well-being.
Worsening glycemic status is linked to increased reports of individual cardiorespiratory symptoms, including dyspnea, cough, chest pain, and arrythmia.
Among women with polycystic ovary syndrome, type two diabetes was more common and diagnosed at a younger age than in control groups.
Study results support an additional management method for glycemic control in patients with T2D.
Researchers examined the efficacy of lifestyle intervention on glycemic control in type 2 diabetes.
Over 150 variables were identified as possible hypoglycemia risk factors.
Endocrinology Advisor Articles
- Efficacy of Novel GLP-1 Receptor Agonist Drug Device Examined
- Higher BUN May Increase Risk for Incident Diabetes
- Alum-Formulated Glutamate Decarboxylase Injections Safe for Prediabetic Children
- Nonhormonal Options Available for Menopause Symptom Relief
- Hormone Therapy After Menopause Onset Reduces Stroke Risk
- New Consensus Recommendations on Use of Continuous Glucose Monitoring
- Does Genetic Susceptibility Lead to Late-Onset Type 1 Diabetes?
- Clinical Outcomes in T2D: Low-Carbohydrate vs Calorie-Restricted Diet
- New Continuous Glucose Monitoring System Now Available for Medicare Patients
- Text Message-Delivered Interventions Effective for Weight Management
- Takeout Food May Increase Adverse Health Consequences in Children
- Plasma Volume Changes Mediate Risk of CV Mortality With Empagliflozin
- Systemic Corticosteroid Use May Increase Fracture Risk in Pediatric Asthma
- Home Visit Program Significantly Lowers Rates of Obesity in Young Children
- Efficacy of Novel GLP-1 Receptor Agonist Drug Device Examined