Type 2 Diabetes Archive

Canagliflozin May Improve Renal Outcomes in Patients With Type 2 Diabetes

Canagliflozin May Improve Renal Outcomes in Patients With Type 2 Diabetes

The renal protective benefit was seen in patients with both reduced (eGFR <60mL/min/1.73m2) and preserved (eGFR ≥60mL/min/1.73m2) renal function.

Consensus Report Defines Treatment Success in β-Cell Replacement Therapy

Consensus Report Defines Treatment Success in β-Cell Replacement Therapy

IPITA and EPITA held a workshop to develop consensus for a joint statement on the definition of function and failure of current and future forms of β-cell replacement therapy.

Eating Pecans May Cut Risk for Cardiovascular Disease, Diabetes

Eating Pecans May Cut Risk for Cardiovascular Disease, Diabetes

Changes in serum insulin and homeostatic model assessment of insulin resistance and beta cell function were significantly greater compared to the control diet

Lactation Lowers Risk for T2D After Gestational Diabetes

Lactation Lowers Risk for T2D After Gestational Diabetes

For women with previous gestational diabetes, lactation is associated with reduced risk of type 2 diabetes, although there is no benefit for long-term lactation.

Skin Nodule Manipulation Leads to Adverse Drug Reactions in a T2D Patient

Skin Nodule Manipulation Leads to Adverse Drug Reactions in a T2D Patient

The patient, a 50-year old male, presented to the emergency department with palpitations and complaints of nausea, retching and diarrhea which he said started after he squeezed a nodule on his thigh.

Diabetes Treatments

Antidiabetic agents for the treatment of diabetes including maintenance and max doses.

Noninvasive CAD Screening May Reduce Cardiac Events in Individuals With Asymptomatic Diabetes

Noninvasive CAD Screening May Reduce Cardiac Events in Individuals With Asymptomatic Diabetes

Compared with standard care, noninvasive coronary artery disease screening reduced cardiac events by 27% in individuals with asymptomatic diabetes. Results justify larger, appropriately powered trials to potentially revisit current recommendations.

Diabetes Does Not Alter Anti-Osteoporotic Treatment Response

Diabetes Does Not Alter Anti-Osteoporotic Treatment Response

Anti-osteoporotic medications (mainly bisphosphonates) seem to equally prevent bone loss, especially in the lumbar spine, in patients with diabetes compared with patients without diabetes.

Grilled Meat, Chicken Increases Risk for Type 2 Diabetes in US Adults

Grilled Meat, Chicken Increases Risk for Type 2 Diabetes in US Adults

Open-flame and/or high-temperature cooking methods (such as grilling/barbecuing, broiling, or roasting) to prepare chicken and red meat are associated with an increased risk of type 2 diabetes.

Risk for Congenital Anomaly With Exposure to Insulin Analogues in the First Trimester

Risk for Congenital Anomaly With Exposure to Insulin Analogues in the First Trimester

Results suggest that first trimester use of insulin analogues does not increase the risk for a congenital anomaly in women with diabetes compared with the use of human insulin.

Successful Hepatitis C Treatment May Reduce Risk for Developing T2D

Successful Hepatitis C Treatment May Reduce Risk for Developing T2D

Among a large US cohort of patients treated for HCV, patients who achieved sustained virologic response demonstrated a substantially lower risk for development of type 2 diabetes than patients with treatment failure.

Safety, Efficacy of Degludec/Liraglutide Fixed-Ratio Combination in Uncontrolled T2D

Safety, Efficacy of Degludec/Liraglutide Fixed-Ratio Combination in Uncontrolled T2D

IDegLira provides an efficacious intensification option with noninferior glycemic control vs basal-bolus in patients with type 2 diabetes receiving 20 to 50 units of basal insulin with no renal impairment and HbA1c levels of 7% to 10%.

Bydureon Single Dose Trays to Be Discontinued

Bydureon Single Dose Trays to Be Discontinued

The Food and Drug Administration (FDA) has issued a discontinuation notice for Bydureon (exenatide extended-release; AstraZeneca) for injectable suspension Single Dose Trays.

Risk Factors for Developing Diabetic Polyneuropathy in Type 2 Diabetes

Risk Factors for Developing Diabetic Polyneuropathy in Type 2 Diabetes

Study provides stronger epidemiological evidence for obesity as a risk factor for diabetic polyneuropathy.

Bydureon Approved for Use With Basal Insulin for Uncontrolled T2D

Bydureon Approved for Use With Basal Insulin for Uncontrolled T2D

The DURATION-7 study examined the effect of Bydureon or placebo as add-on therapy to insulin glargine, with or without metformin, in adults with T2D.

Chronic Kidney Disease May Be Common in Veterans Prior to Diabetes Diagnosis

Chronic Kidney Disease May Be Common in Veterans Prior to Diabetes Diagnosis

The study adds insight to the extent of both racial and regional variations in the prevalence of chronic kidney disease while calling attention to the magnitude of this disease in patients prior to being diagnosed with diabetes.

Cardiovascular Outcomes of SGLT-2i vs Other Glucose-Lowering Drugs in T2D

Cardiovascular Outcomes of SGLT-2i vs Other Glucose-Lowering Drugs in T2D

A recent study evaluated the effects of SGLT-2i and other glucose-lowering drugs on cardiovascular event outcomes in patients with type 2 diabetes from 6 countries in 3 world regions.

Independent Risk Pathways Shown for Diabetes and Obesity in Adults With Serious Mental Illness

Independent Risk Pathways Shown for Diabetes and Obesity in Adults With Serious Mental Illness

Given the high risk for metabolic disorder and type 2 diabetes, clinicians should select psychotropic medications carefully and monitor metabolic conditions regularly in their patients with serious mental illness.

Canakinumab Does Not Appear to Prevent Diabetes Onset

Canakinumab Does Not Appear to Prevent Diabetes Onset

The new analysis focuses on the remaining 4960 patients, who had prediabetes at the start of the trial.

Food Insecurity Tied to Poor Glycemic Control in Diabetes

Food Insecurity Tied to Poor Glycemic Control in Diabetes

Food insecurity screening and interventions may help improve glycemic control for vulnerable patients.

Low-Grade Inflammatory Markers May Help Differentiate Diabetes Diagnoses in Adults

Low-Grade Inflammatory Markers May Help Differentiate Diabetes Diagnoses in Adults

Study provided evidence of significant differences in median serum concentrations of circulating adipose-related inflammatory biomarkers across the main diabetes types.

Tresiba Label Updated With Data on Severe Hypoglycemia, CV Outcomes

Tresiba Label Updated With Data on Severe Hypoglycemia, CV Outcomes

The Tresiba label was updated to reflect safety outcomes from the DEVOTE trial.

Toujeo Max SoloStar Gets FDA Approval for Patients With Diabetes

Toujeo Max SoloStar Gets FDA Approval for Patients With Diabetes

Sanofi announced that the Food and Drug Administration (FDA) has approved Toujeo (insulin glargine 300 Units/mL) Max SoloStar, a long-acting insulin pen that holds 900 Units of Toujeo and provides up to 160 Units/mL per injection.

Dipeptidyl Peptidase-4 Inhibitors in T2D Linked to IBD

Dipeptidyl Peptidase-4 Inhibitors in T2D Linked to IBD

Dipeptidyl peptidase-4 inhibitors are associated with increased risk of inflammatory bowel disease among patients with type 2 diabetes.

Surgical Treatment Better Than Medical Therapy in Severely Obese Adolescents With T2D

Surgical Treatment Better Than Medical Therapy in Severely Obese Adolescents With T2D

Researchers compared glycemic control in cohorts of severely obese adolescents with type 2 diabetes undergoing medical and surgical interventions.

No Cardiovascular Benefit With Fenofibrate in T2D and Hypertriglyceridemia

No Cardiovascular Benefit With Fenofibrate in T2D and Hypertriglyceridemia

Statins were associated with a reduction in mortality but there was no significant difference in the composite end point with fenofibrates alone or in combination with statins.

Primary Prevention Outcomes With Aspirin in T2D and Heart Failure

Primary Prevention Outcomes With Aspirin in T2D and Heart Failure

In patients with type 2 diabetes and heart failure, primary prevention with aspirin reduced all-cause mortality but increased nonfatal myocardial infarction and stroke.

Reducing Total Daily Insulin Dose in T2D: 3-Meal vs 6-Meal Diet

Reducing Total Daily Insulin Dose in T2D: 3-Meal vs 6-Meal Diet

In people with obesity and type 2 diabetes, a meal schedule that includes a high-energy breakfast promotes weight loss, improves diabetes, and decreases the need for insulin.

Effect of HbA1c and Perioperative Glucose on Postoperative Mortality

Effect of HbA1c and Perioperative Glucose on Postoperative Mortality

Perioperative glucose control may be more important than preoperative HbA1c in predicting 30-day postoperative mortality.

Separate Pathways for T2D and Obesity in Patients With Mental Illness

Separate Pathways for T2D and Obesity in Patients With Mental Illness

New research suggests that there are separate pathways for the development of type 2 diabetes and obesity in patients with serious mental illness and demonstrate that there are important effects associated with sex and race or ethnicity.

Weight Changes Influence Risk of Diabetes Over Course of Life

Weight Changes Influence Risk of Diabetes Over Course of Life

Changes in weight influence the risk of diabetes, with lower risk of diabetes for obese individuals who lose weight vs stable obesity.

Very Few People Engage in Lifestyle Behavior Changes to Reduce T2D Risk

Very Few People Engage in Lifestyle Behavior Changes to Reduce T2D Risk

Researchers conducted an analysis to better understand what proportion of adults engage in lifestyle behaviors known the reduce the risk of type 2 diabetes.

Global Costs of Diabetes Will Substantially Increase by 2030

Global Costs of Diabetes Will Substantially Increase by 2030

Researchers modeled the absolute and gross domestic product-relative economic burden of diabetes in individuals aged 20 to 79 years using epidemiological and demographic data as well as recent GDP forecasts for 180 countries.

American College of Physicians Releases 4 Guidelines for HbA1c Targets in T2D

American College of Physicians Releases 4 Guidelines for HbA1c Targets in T2D

Clinicians should reevaluate HbA1c levels and revise treatment strategies on the basis of changes in the balance of benefits and harms due to changed costs of care and patient preferences, general health, and life expectancy.

Obesity, Diabetes May Increase Risk of Reoperation After Microvascular Decompression

Obesity, Diabetes May Increase Risk of Reoperation After Microvascular Decompression

Microvascular decompression for trigeminal neuralgia, hemifacial spasm, and glossopharyngeal neuralgia was found to be a largely safe procedure, but patients with diabetes or obesity are an increased risk for reoperation within 30 days.

Pattern of Placebo Response in Oral Antihyperglycemic Agent Drug Trials

Pattern of Placebo Response in Oral Antihyperglycemic Agent Drug Trials

Placebo-treated patients with diabetes commonly experienced a reduction in HbA1c, more markedly in augmented vs exclusively placebo-controlled treatment arms.

Plasma Leptin Levels Associated With Sleep Quality in Obese Patients With T2D

Plasma Leptin Levels Associated With Sleep Quality in Obese Patients With T2D

Plasma leptin levels are independently associated with sleep quality in obese patients with type 2 diabetes, but not in those who are not obese.

Sulfonylureas and Risk of Sudden Cardiac Arrest, Ventricular Arrhythmia Examined

Sulfonylureas and Risk of Sudden Cardiac Arrest, Ventricular Arrhythmia Examined

Study examined the association between individual antidiabetic sulfonylureas and outpatient-originating sudden cardiac arrest and ventricular arrhythmia.

Ovarian Cancer in T2D: No Link Between Metformin or Statins

Ovarian Cancer in T2D: No Link Between Metformin or Statins

In women with type 2 diabetes, no evidence was found of an association between the use of metformin or statins and the incidence of ovarian cancer.

Higher Obesity-Related Cancer Risk in Women With Type 2 Diabetes

Higher Obesity-Related Cancer Risk in Women With Type 2 Diabetes

Women, not men, with T2D had an increased obesity-related standardized cancer incidence compared with women in the general population as early as 5 years before diabetes diagnosis.

Effect of Fenofibrate Varies Widely in Type 2 Diabetes

Effect of Fenofibrate Varies Widely in Type 2 Diabetes

The method of individualized treatment effect prediction of fenofibrate on major cardiovascular events risk reduction in T2D can be used to guide clinical decision-making.

Effect of Glycemic Control During Labor on Neonatal Hypoglycemia Examined

Effect of Glycemic Control During Labor on Neonatal Hypoglycemia Examined

High-quality studies are needed to determine whether tight intrapartum glycemic control is superior to more relaxed glycemic targets intrapartum for women with diabetes in pregnancy.

COX-2 Inhibitors Plus Metformin Lower Joint Replacement Rates in Osteoarthritis With T2D

COX-2 Inhibitors Plus Metformin Lower Joint Replacement Rates in Osteoarthritis With T2D

Researchers compared the effects of combined metformin and COX-2 inhibitor therapy vs COX-2 therapy alone on joint replacement surgery rates.

Efficacy of Concomitant DPP-4 Inhibitor With Insulin Glargine in T2D

Efficacy of Concomitant DPP-4 Inhibitor With Insulin Glargine in T2D

Study assessed the efficacy and safety of insulin glargine 300 U/mL vs glargine 100 U/mL with and without concomitant DPP-4 inhibitor use in people with type 2 diabetes.

Earlier Diagnosis of Type 2 Diabetes Increases Mortality Risk

Earlier Diagnosis of Type 2 Diabetes Increases Mortality Risk

Study examined the effect of age at diagnosis of type 2 diabetes on the risk of all-cause and cause-specific mortality over 15 years.

Metformin After Insulin Therapy Induction Beneficial in Long-Term

Metformin After Insulin Therapy Induction Beneficial in Long-Term

After induction short-term intensive insulin therapy, metformin is superior to intermittent IIT for maintaining beta-cell function and glycemic control over 2 years.

Greater Benefits for Patients With T2D After RYGB Surgery vs Other Management Options

Greater Benefits for Patients With T2D After RYGB Surgery vs Other Management Options

For obese adults with type 2 diabetes, Roux-en-Y gastric bypass surgery is associated with greater weight loss, lower HbA1c, and reduced cardiovascular risk compared with intensive medical diabetes and weight management.

T2D May Play a Protective Role Against Developing Aortic Diseases

T2D May Play a Protective Role Against Developing Aortic Diseases

The novel findings in this study suggest that patients with type 2 diabetes have a significantly reduced risk for short-term mortality after hospitalization for aortic aneurysm compared with population-based control subjects.

Reducing Eating Speed May Prevent Obesity in Type 2 Diabetes

Reducing Eating Speed May Prevent Obesity in Type 2 Diabetes

Eating speed can affect changes in obesity, body mass index, and waist circumference in patients with type 2 diabetes.

Diabetes Mortality Trends in Adults With Low eGFR, No Albuminuria

Diabetes Mortality Trends in Adults With Low eGFR, No Albuminuria

A recent study examined mortality trends in adults with diabetes and assessed albumin-to-creatinine ratios and estimated glomerular filtration rates.

Risk Factors for Diabetes May Be Identified 20 Years Before Diagnosis

Risk Factors for Diabetes May Be Identified 20 Years Before Diagnosis

Risk of developing type 2 diabetes is associated with subtle elevations of glucose and lipids more than 20 years before diagnosis.

Physician-Patient Communication Key for Improving Diabetes Care

Physician-Patient Communication Key for Improving Diabetes Care

Diabetes care can be improved with enhanced communication between providers and patients and improved communication between members of the primary care team.

Metformin Safe in T2D With Moderate to Severe Chronic Kidney Disease

Metformin Safe in T2D With Moderate to Severe Chronic Kidney Disease

This is the first study to have validated a metformin dose adjustment as a function of the estimated glomerular filtration rate in patients with type 2 diabetes and chronic kidney disease.

Increased Risk for Severe Hypoglycemic Events Associated With CV Outcomes

Increased Risk for Severe Hypoglycemic Events Associated With CV Outcomes

The bidirectional relationship between severe hypoglycemic events and cardiovascular outcomes suggests that there may be a common "frail" type 2 diabetes phenotype of patients who are susceptible to both of these events.

Women With T1D, T2D Receiving Increased Intervention in Pregnancy

Women With T1D, T2D Receiving Increased Intervention in Pregnancy

Higher rates of operative delivery and falling gestational age at delivery suggest that this is either reflected by, or despite, increasing obstetric intervention.

Two New Diabetes Medications Now Available

Two New Diabetes Medications Now Available

Two recently-approved diabetes treatments, a semaglutide injection and an insuline aspart injection, are now available in pharmacies across the United States.

Safety, Efficacy of Semaglutide for Inadequately Controlled T2D

Safety, Efficacy of Semaglutide for Inadequately Controlled T2D

Patients with type 2 diabetes who received once-weekly semaglutide had statistically greater reductions in HbA1c and body weight compared with those treated with dulaglutide.

Updated Standards of Medical Care in Diabetes Focuses on Cardiovascular Disease

Updated Standards of Medical Care in Diabetes Focuses on Cardiovascular Disease

ADA's recommendations reflect the latest advances in evidence-based research to improve care for millions of people with diabetes.

Assessing the Link Between Chronic Migraine and Insulin Resistance

Assessing the Link Between Chronic Migraine and Insulin Resistance

Study assessed the relationship of fasting neuropeptide Y with insulin resistance, β-cell function, and glucagon-like peptide-1 secretion in nonobese female patients with chronic migraine.

Remission of T2D Possible With Strict Glycemic Control

Remission of T2D Possible With Strict Glycemic Control

Stricter glycemic control during short-term intensive insulin therapy for newly diagnosed type 2 diabetes patients is associated with a higher likelihood of remission at 1 year.

Duration of Prediabetes, Diabetes Independently Associated With Subclinical Atherosclerosis, Cardiac Dysfunction

Duration of Prediabetes, Diabetes Independently Associated With Subclinical Atherosclerosis, Cardiac Dysfunction

Data emphasize the importance of early identification and management of those at risk for diabetes and prediabetes in order to limit exposure to the adverse cardiovascular effects of a longer duration of these conditions.

Higher Risk for Adverse Pregnancy Outcomes in Women With Pregestational Diabetes on Metformin

Higher Risk for Adverse Pregnancy Outcomes in Women With Pregestational Diabetes on Metformin

Higher risks for adverse pregnancy outcomes observed in pregnant women taking metformin for pregestational diabetes are not a result of metformin, but diabetes.

Effects of Sitagliptin on Standardized Insulin Secretion, B-Cell Function

Effects of Sitagliptin on Standardized Insulin Secretion, B-Cell Function

A single dose of the dipeptidyl peptidase-4 inhibitor sitagliptin is associated with increased standardized insulin secretion, with no impact on β-cell glucose sensitivity.

Type 2 Diabetes Treatment Adherence Varies Across Medication Classes

Type 2 Diabetes Treatment Adherence Varies Across Medication Classes

There is considerable variation in adherence across medication classes for the treatment of type 2 diabetes, including sulfonylureas, thiazolidinediones, and metformin.

Gestational Diabetes May Increase Risk for Hypertension, Ischemic Heart Disease, T2D

Gestational Diabetes May Increase Risk for Hypertension, Ischemic Heart Disease, T2D

Clinical guidelines should include postpartum screening and management for all cardiovascular risk factors in women diagnosed with gestational diabetes and not restrict it to diabetes.

Update on Discontinuation of Tanzeum Injections

Update on Discontinuation of Tanzeum Injections

The initial decision to discontinue Tanzeum was announced in August 2017 due to limited prescribing of the drug and not because of safety concerns.

No Increased Risk for Type 2 Diabetes, Hypertension in Living Kidney Donors

No Increased Risk for Type 2 Diabetes, Hypertension in Living Kidney Donors

Living kidney donors have no increased risks for all-cause mortality, cardiovascular disease, hypertension, type 2 diabetes, or adverse psychological health outcomes.

T1D, T2D May Have Protective Effects on Risk for Migraine

T1D, T2D May Have Protective Effects on Risk for Migraine

Results from a study investigating diabetes and migraine in the Norwegian population show that type 1 and type 2 diabetes were significantly associated with a decreased risk for migraine.

Balance Training May Reduce Fall Risk in Older Adults With T2D

Balance Training May Reduce Fall Risk in Older Adults With T2D

Balance training interventions (supervised and unsupervised) led to significant improvements in a number of physiological measures, ultimately reflected in a decline in fall risk for older adults with T2D.

Sulfonylureas May Increase Tuberculosis Risk in Type 2 Diabetes

Sulfonylureas May Increase Tuberculosis Risk in Type 2 Diabetes

Patients with type 2 diabetes treated with sulfonylureas may be at a higher risk of contracting tuberculosis, compared with patients treated with metformin.

Adding Ezetimibe to Statin Therapy: Cardiovascular Outcomes in Diabetes

Adding Ezetimibe to Statin Therapy: Cardiovascular Outcomes in Diabetes

In patients with an acute coronary syndrome and LDL-C >50 mg/dL, healthcare providers should consider adding ezetimibe to statin therapy to reduce the risk of cardiovascular events.

Type 1 Diabetes Associated With Higher Rates of Serious Infection

Type 1 Diabetes Associated With Higher Rates of Serious Infection

Patients with diabetes had higher rates for all 19 infection categories with the highest incidence rate ratios seen for bone and joint infections, sepsis, and cellulitis.

First-line Metformin Use for Type 2 Diabetes Increases Over Last Decade

First-line Metformin Use for Type 2 Diabetes Increases Over Last Decade

Among patients with type 2 diabetes initiating antidiabetes drugs, first-line use of metformin has increased since 2005.

Differences in Modifiable Risk Factors Contribute to Increased T2D Risk Among Blacks

Differences in Modifiable Risk Factors Contribute to Increased T2D Risk Among Blacks

Differences in traditional modifiable diabetes risk factors between black and white individuals may contribute to the racial disparity in diabetes incidence in middle age.

Interactive, Personalized Simulation May Change Behavioral Intentions in T2D

Interactive, Personalized Simulation May Change Behavioral Intentions in T2D

An interactive, personalized simulation can change behavioral intentions among individuals with type 2 diabetes.

Effect of Intra-Articular Depot Betamethasone on Insulin Resistance in T2D

Effect of Intra-Articular Depot Betamethasone on Insulin Resistance in T2D

Patients identified with increased insulin resistance following intra-articular corticosteroid injection or any systemic steroid treatment might need a special emphasis regarding management and followup.

Takeout Food May Increase Adverse Health Consequences in Children

Takeout Food May Increase Adverse Health Consequences in Children

Efforts to reduce takeaway meal consumption in children could have both short-term and long-term health benefits.

Efficacy of Novel GLP-1 Receptor Agonist Drug Device Examined

Efficacy of Novel GLP-1 Receptor Agonist Drug Device Examined

In this phase 3 study, statistically and clinically meaningful improvements in HbA1c, body weight, and the proportion of patients achieving goal HbA1c <7% (53mmol/mol) were demonstrated with 2 doses of ITCA 650 vs placebo.

Higher BUN May Increase Risk for Incident Diabetes

Higher BUN May Increase Risk for Incident Diabetes

Findings showed that as the estimated glomerular filtration rate decreased and the blood urea nitrogen level increased, the risk for incident diabetes became progressively more pronounced.

QoL, Self-Management Improved in T2D With Community-Based Program

QoL, Self-Management Improved in T2D With Community-Based Program

A community-based program improves quality of life and self-management in older adults with type 2 diabetes and comorbidities.

New Formulation of Once-Weekly Exenatide Available for T2D

New Formulation of Once-Weekly Exenatide Available for T2D

A new formulation of exenatide extended-release that is supplied in a once-weekly, single-dose autoinjector device that comes prefilled with a pre-attached hidden needle, is now available.

Individualized Glycemic Control in T2D May Be Cost-Effective

Individualized Glycemic Control in T2D May Be Cost-Effective

An individualized approach to glycemic control in type 2 diabetes is likely to reduce costs and improve quality of life.

Pediatric T2D: Lower HbA1c Predicts Better Outcomes With Metformin Monotherapy

Pediatric T2D: Lower HbA1c Predicts Better Outcomes With Metformin Monotherapy

Findings accentuate the much greater concern regarding clinical outcomes in participants who did not respond to metformin monotherapy.

Long-Term Mortality Increased in Patients With T2D in All Weight Categories

Long-Term Mortality Increased in Patients With T2D in All Weight Categories

For patients with type 2 diabetes, all weight categories show increased long-term mortality, with a nadir at a body mass index of 25 to <30.

Clinical Outcomes in T2D: Low-Carbohydrate vs Calorie-Restricted Diet

Clinical Outcomes in T2D: Low-Carbohydrate vs Calorie-Restricted Diet

Well-constructed and individualized nutrition therapy programs were found to effectively reduce HbA1c and BMI in individuals with type 2 diabetes.

Weight Management With Routine Primary Care Effective for T2D Control, Remission

Weight Management With Routine Primary Care Effective for T2D Control, Remission

The DiRECT study provides the first evidence from a randomized trial of a dietary and lifestyle intervention with remission of type 2 diabetes as a primary outcome.

Preoperative Liraglutide May Stabilize Postoperative Plasma Glucose in T2D

Preoperative Liraglutide May Stabilize Postoperative Plasma Glucose in T2D

For patients with type 2 diabetes undergoing non-cardiac surgery, premedication with liraglutide is associated with reduced median plasma glucose 1 hour postoperatively.

Glucose-Responsive Exendin-4 Delivery Device for T2D Holds Promise

Glucose-Responsive Exendin-4 Delivery Device for T2D Holds Promise

A smart exendin-4 delivery device is a promising therapeutic option for type 2 diabetes that can provide safe, long-term, and on-demand Ex4 therapy.

FDA Approves First Shock Wave Device for Treating Diabetic Foot Ulcers

FDA Approves First Shock Wave Device for Treating Diabetic Foot Ulcers

The FDA has granted marketing clearance of the first shock wave device intended for use in the treatment of chronic, full-thickness diabetic foot ulcers.

Intensive Blood Pressure Lowering Reduces CV Events Similarly in Patients With/Without T2D

Intensive Blood Pressure Lowering Reduces CV Events Similarly in Patients With/Without T2D

Researchers assessed the effect of both type 2 diabetes and baseline cardiovascular disease risk on the treatment effect of intensive blood pressure lowering based on data and pooled analysis from 14,094 patients.

CV Event Prediction, Risk Assessment in Type 2 Diabetes

CV Event Prediction, Risk Assessment in Type 2 Diabetes

Risk of cardiovascular events in people with type 2 diabetes and subgroups of coronary artery disease was examined.

FDA Approves 3 New Drugs for T2D in Adults

FDA Approves 3 New Drugs for T2D in Adults

Steglatro is indicated as adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus, and Steglujan is indicated as adjunct when treatment with both ertugliflozin and sitagliptin are appropriate.

Positive Antihyperglycemic, Metabolic Effects With Ranolazine in Patients With Diabetes

Positive Antihyperglycemic, Metabolic Effects With Ranolazine in Patients With Diabetes

While there is increasing positive data for the utilization of ranolazine, a majority of the data did not come from large randomized controlled trials that looked at metabolic parameters as their primary end point.

Corticosteroids Linked With Risk for Fracture, VTE, Sepsis in Diabetes

Corticosteroids Linked With Risk for Fracture, VTE, Sepsis in Diabetes

Corticosteroids should be used with caution in patients with diabetes and mitigating factors should be considered.

Alogliptin Associated With Lower Fracture Risk Than Linagliptin, Saxagliptin in T2D

Alogliptin Associated With Lower Fracture Risk Than Linagliptin, Saxagliptin in T2D

Network meta-analysis provided some information on differences between DPP-4 inhibitors, traditional anti-diabetes agents, and placebo in bone fracture.

Standard Care vs Telemedicine for Diabetic Foot Ulcer Follow-up Care

Standard Care vs Telemedicine for Diabetic Foot Ulcer Follow-up Care

Patients from 3 sites participated in a trial examining the noninferiority of telemedicine vs standard outpatient care for diabetic foot ulcer follow-up treatment.

Urinary Albumin-to-Creatinine Ratio Aids CV Risk Assessment in T2D

Urinary Albumin-to-Creatinine Ratio Aids CV Risk Assessment in T2D

Urinary albumin-to-creatinine ratio can be independently associated with various adverse CV outcomes.

Optimal Dose of Linagliptin Determined for Pediatric T2D

Optimal Dose of Linagliptin Determined for Pediatric T2D

Study sought to determine the optimal dosing of linagliptin for the treatment of children with type 2 diabetes.

Measuring Quality of Life Important When Evaluating Diabetes Treatments

Measuring Quality of Life Important When Evaluating Diabetes Treatments

Patients with diabetes report worse quality of life with more intensified treatment, demonstrating the importance of measuring quality of life outcomes when evaluating diabetes treatments.

Prediabetes Diagnosis Categorized as Diabetes With 2-Hour Plasma Glucose Test

Prediabetes Diagnosis Categorized as Diabetes With 2-Hour Plasma Glucose Test

Investigators sought to examine whether individuals with prediabetes, based on A1c and fasting plasma glucose levels, would have a diagnosis of diabetes when using a 2-hour plasma glucose test.

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