Type 1 Diabetes

Glycemic Control Variations for Children, Adolescents With T1D in High-Income Countries

Glycemic Control Variations for Children, Adolescents With T1D in High-Income Countries

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Investigators examined glycemic control variations in 8 high-income countries from multicenter registries in children with type 1 diabetes.

Dual-Hormone System May Lower Time in Hypoglycemia in T1D

Dual-Hormone System May Lower Time in Hypoglycemia in T1D

For physically active adults with type 1 diabetes, the addition of glucagon delivery to a closed-loop system using wearable sensors with automated exercise detection is associated with reduced hypoglycemia.

Exceptional Glycemic Control With Very Low-Carbohydrate Diet

Exceptional Glycemic Control With Very Low-Carbohydrate Diet

For children and adults with type 1 diabetes, consuming a very low-carbohydrate diet is associated with exceptional glycemic control.

Improved glycemic control in type 1 diabetes with very low-carbohydrate diets

A survey of individuals with type 1 diabetes consuming a very low-carbohydrate diet indicated that many study participants were able to maintain glycemic control within national ideal glycemic target ranges.

FDA: REMS No Longer Needed for Inhaled Insulin Afrezza

FDA: REMS No Longer Needed for Inhaled Insulin Afrezza

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Upon review of the proposed supplemental New Drug Application (sNDA), the FDA has determined that the communication plan is no longer needed as an element of the REMS to ensure the benefits of Afrezza outweigh its risks.

Brief Educational Intervention Improves Awareness in Severe Hypoglycemia in T1D

Brief Educational Intervention Improves Awareness in Severe Hypoglycemia in T1D

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Brief structured education in addition to informed support in active insulin dose self-adjustment underpinned by targeted self-monitoring of blood glucose lead to sustained falls in severe hypoglycemia rates in individuals at high risk.

Mitochondrial, Muscle Ultrastructural Abnormalities Observed in Skeletal Muscle of Young Adults With T1D

Mitochondrial, Muscle Ultrastructural Abnormalities Observed in Skeletal Muscle of Young Adults With T1D

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The study highlights mitochondrial and autophagic differences in the muscles of young adults with type 1 diabetes with moderate glycemic control who exceed recommended activity levels.

Challenges of Long-Distance Air Travel With Type 1 Diabetes

Challenges of Long-Distance Air Travel With Type 1 Diabetes

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Long-distance air travel presents numerous unique challenges for insulin-treated patients with diabetes. More accessible and adequate sources of guidance are needed to facilitate travel planning among this patient population.

CDC Reports on Diabetes Prevalence by Type in the United States

CDC Reports on Diabetes Prevalence by Type in the United States

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The CDC conducted a study to estimate the prevalence of diagnosed diabetes among adults in 2016 by primary type.

Risk for Fetal Loss Early in Pregnancy Not Greater With Noninsulin vs Insulin Therapy

Risk for Fetal Loss Early in Pregnancy Not Greater With Noninsulin vs Insulin Therapy

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Compared to standard insulin treatment, noninsulin antidiabetic agents did not present an increased risk for fetal losses or major malformations when used in the first trimester of pregnancy.

Artificial Pancreas Treatment Efficacious for Type 1 Diabetes

Artificial Pancreas Treatment Efficacious for Type 1 Diabetes

For patients with type 1 diabetes, artificial pancreas treatment is efficacious, increasing the proportion of time spent in the near normoglycemic range.

Young Adults With Type 1 Diabetes Show Muscle Metabolic Deficiencies

Young Adults With Type 1 Diabetes Show Muscle Metabolic Deficiencies

Physically active young adults with type 1 diabetes have alterations in mitochondrial ultrastructure and bioenergetics within skeletal muscle.

Autism Does Not Affect Metabolic Control in Type 1 Diabetes

Autism Does Not Affect Metabolic Control in Type 1 Diabetes

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Awareness of ASD and its manifestations and comorbidities remain imperative in the treatment of T1D, as both conditions require long-term medical follow-up to continue improving diabetes care and metabolic control outcomes.

Distinct Mechanisms Underlie Nerve Damage in Peripheral Neuropathy in T1D vs T2D

Distinct Mechanisms Underlie Nerve Damage in Peripheral Neuropathy in T1D vs T2D

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The type of sciatic nerve lesions observed in patients with diabetic peripheral neuropathy was found to differ in type 1 and type 2 diabetes.

Pharmacists Can Help With Diabetes Management via Telemedicine

Pharmacists Can Help With Diabetes Management via Telemedicine

Telemedicine could provide real-time feedback loop and allow pharmacists to help patients self-manage.

Continuous Glucose Monitoring Cost-Effective in Type 1 Diabetes

Continuous Glucose Monitoring Cost-Effective in Type 1 Diabetes

For adults with type 1 diabetes with suboptimal control despite using multiple insulin injections, continuous glucose monitoring seems cost-effective, with improved glucose control.

Altered Neural Responses in Memory Processing With Type 1 Diabetes

Altered Neural Responses in Memory Processing With Type 1 Diabetes

Young adults with type 1 diabetes have altered neural responses during working memory processing.

Glycemic Extremes in T1D Effect Cognitive Skills in Children

Glycemic Extremes in T1D Effect Cognitive Skills in Children

Researchers conducted a systematic literature review to identify studies on cognitive function in children with type 1 diabetes.

Consensus Report Defines Treatment Success in β-Cell Replacement Therapy

Consensus Report Defines Treatment Success in β-Cell Replacement Therapy

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IPITA and EPITA held a workshop to develop consensus for a joint statement on the definition of function and failure of current and future forms of β-cell replacement therapy.

Diabetes Does Not Alter Anti-Osteoporotic Treatment Response

Diabetes Does Not Alter Anti-Osteoporotic Treatment Response

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Anti-osteoporotic medications (mainly bisphosphonates) seem to equally prevent bone loss, especially in the lumbar spine, in patients with diabetes compared with patients without diabetes.

Risk Factors for Cardiovascular Disease in Youth With Type 1 Diabetes

Risk Factors for Cardiovascular Disease in Youth With Type 1 Diabetes

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Early treatment of cardiovascular disease risk factors such as dyslipidemia and hypertension will have long-term benefits with low risk and cost and should be more widely used in pediatric type 1 diabetes care.

Islet Transplantation Improves Quality of Life in Type 1 Diabetes

Islet Transplantation Improves Quality of Life in Type 1 Diabetes

There are significant improvements in health-related quality of life following islet transplantation in patients with type 1 diabetes complicated by severe hypoglycemia.

Accuracy of Novel Implantable Continuous Glucose Monitoring Device Assessed

Accuracy of Novel Implantable Continuous Glucose Monitoring Device Assessed

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Researchers assessed the safety and accuracy of an implantable continuous glucose measurement in adults diagnosed with type 1 and type 2 diabetes.

Low-Grade Inflammatory Markers May Help Differentiate Diabetes Diagnoses in Adults

Low-Grade Inflammatory Markers May Help Differentiate Diabetes Diagnoses in Adults

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Study provided evidence of significant differences in median serum concentrations of circulating adipose-related inflammatory biomarkers across the main diabetes types.

Dexcom G6 Integrated Continuous Glucose Monitoring System Gets FDA Approval

Dexcom G6 Integrated Continuous Glucose Monitoring System Gets FDA Approval

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The FDA reviewed data for the device through the de novo premarket review pathway, a regulatory pathway for novel, low-to-moderate-risk devices that are not substantially equivalent to an already legally marketed device.

Toujeo Max SoloStar Gets FDA Approval for Patients With Diabetes

Toujeo Max SoloStar Gets FDA Approval for Patients With Diabetes

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Sanofi announced that the Food and Drug Administration (FDA) has approved Toujeo (insulin glargine 300 Units/mL) Max SoloStar, a long-acting insulin pen that holds 900 Units of Toujeo and provides up to 160 Units/mL per injection.

Physiologic Response to Glucagon in Type 1 Diabetes After Alcohol Consumption

Physiologic Response to Glucagon in Type 1 Diabetes After Alcohol Consumption

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Researchers assessed whether alcohol intake affects response to glucagon in individuals with type 1 diabetes.

Sotagliflozin NDA Submitted to FDA for Type 1 Diabetes

Sotagliflozin NDA Submitted to FDA for Type 1 Diabetes

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The NDA is based on results from a large placebo-controlled, phase 3 trial that included 1402 patients with type 1 diabetes who were receiving insulin therapy.

Influence of Gender on Cardiovascular Risk and Glycemic Control in T1D

Influence of Gender on Cardiovascular Risk and Glycemic Control in T1D

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Researchers assessed differences in glycemic control, major cardiovascular risk factors, diabetes-related complications, sexual dysfunction prevalence, and endothelial function in young men and women with type 1 diabetes.

Closed-Loop Insulin Delivery Offers Best Outcomes for Pregnant Women With T1D

Closed-Loop Insulin Delivery Offers Best Outcomes for Pregnant Women With T1D

For pregnant women with type 1 diabetes, a closed-loop system is associated with comparable glucose control and significantly less hypoglycemia than sensor-augmented pump therapy.

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