Type 1 Diabetes

Bone Mineral Density Loss Eventually Stabilizes in Men With Type 1 Diabetes

Bone Mineral Density Loss Eventually Stabilizes in Men With Type 1 Diabetes

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Investigators determined that reductions in bone mineral density in men with type 1 diabetes occur early in the course of the disease.

Adjunct Dapagliflozin Improves Glycemic Control But Increases Ketoacidosis in T1D

Adjunct Dapagliflozin Improves Glycemic Control But Increases Ketoacidosis in T1D

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Investigators examined safety and efficacy of adjunct therapy to insulin for patients with type 1 diabetes who are not adequately controlled.

ADA Releases Updated Guidelines for Managing Pediatric Type 1 Diabetes

ADA Releases Updated Guidelines for Managing Pediatric Type 1 Diabetes

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It is critical for us to remember that children are not little adults. Pediatric-onset diabetes is different from adult-onset diabetes due to its distinct epidemiology, pathophysiology, developmental considerations, and response to therapy.

High Albumin-to-Creatinine Ratio Associated With Increased Risk for Microalbuminuria and Future CVD in Adolescents

High Albumin-to-Creatinine Ratio Associated With Increased Risk for Microalbuminuria and Future CVD in Adolescents

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The association between albumin-to-creatinine ratio and risk for diabetic nephropathy and CVD was examined over 2 to 4 years.

Smoothing the Care Team Transition for Youth With Type 1 Diabetes

Smoothing the Care Team Transition for Youth With Type 1 Diabetes

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The transition from pediatric to adult care for type 1 diabetes should be a gradual process, with a plan to make the change when the patient is ready, not at a pre-determined time.

One in Four Older Adults With Diabetes Uses Alternative Meds

One in Four Older Adults With Diabetes Uses Alternative Meds

More than 25 percent of older U.S. adults with diabetes use some type of complementary and alternative medicine.

Reducing Diabetes Distress in Adults With T1D: A Comparison of 2 Interventions

Reducing Diabetes Distress in Adults With T1D: A Comparison of 2 Interventions

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Investigators compared 2 interventions to reduce diabetes distress and improve glycemic control in patients with T1D.

Health Coverage Interruptions Common in Adults With T1DM

Health Coverage Interruptions Common in Adults With T1DM

Interruptions in private health insurance coverage are common among U.S. adults with type 1 diabetes and are associated with an increase in glycated hemoglobin and in use of acute care services.

Risk for Heart Failure Up in ALVSD Patients With Diabetes

Risk for Heart Failure Up in ALVSD Patients With Diabetes

For patients with asymptomatic left ventricular systolic dysfunction (ALVSD), those with diabetes have increased risk of heart failure development and hospitalization.

G6 CGM System Offers Improved Accuracy in Youth and Adults With Diabetes

G6 CGM System Offers Improved Accuracy in Youth and Adults With Diabetes

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Investigators evaluate the performance of the G6 factory-calibrated continuous glucose monitoring system over 10 days.

Detecting and Treating Depression in Diabetes

Detecting and Treating Depression in Diabetes

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Comorbid depression, when not well controlled, can affect one's ability to self-manage diabetes. There can be loss of interest in making proper lifestyle choices, monitoring glucose levels, and taking one's medicines.

Anti-Thymocyte Globulin Reduced HbA1C in Newly Diagnosed Type 1 Diabetes

Anti-Thymocyte Globulin Reduced HbA1C in Newly Diagnosed Type 1 Diabetes

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Investigators examined the effects of antithymocyte globulin with or without pegylated granulocyte colony-stimulating factor on β-cell function and HbA1C.

Masked High Blood Pressure and Arterial Stiffness in Type 1 Diabetes

Masked High Blood Pressure and Arterial Stiffness in Type 1 Diabetes

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Ambulatory blood pressure monitoring in addition to office readings may effectively be able to identify individuals who are at high risk for CVD in T1D.

Hippocampal Calcification Associated With Aging, Diabetes, and Smoking

Hippocampal Calcification Associated With Aging, Diabetes, and Smoking

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Investigators aim to identify risk factors for hippocampal calcifications and to investigate the relationship between hippocampal calcifications and cognitive function.

Risk for Diabetic Retinopathy With Incretin-Based Therapies

Risk for Diabetic Retinopathy With Incretin-Based Therapies

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Investigators examined whether incretin-based therapies increase the risk for diabetic retinopathy compared with other antihyperglycemic agents.

PM<sub>2.5</sub> Contributes to Burden of Diabetes Mellitus Globally

PM2.5 Contributes to Burden of Diabetes Mellitus Globally

Particulate matter (PM) with a diameter of less than 2.5 micrograms per cubic meter of air (PM2.5) makes a substantial contribution to the burden of diabetes.

Circadian System, Misalignment Have Distinct Impact on Insulin

Circadian System, Misalignment Have Distinct Impact on Insulin

The endogenous circadian system, behavioral cycle, and circadian misalignment have distinct effects on insulin sensitivity and β-cell function.

Calcium Channel Blocker May Benefit Patients With Type 1 Diabetes

Calcium Channel Blocker May Benefit Patients With Type 1 Diabetes

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For this study, researchers conducted a randomized, double-blind, placebo-controlled Phase 2 trial (N=24) to assess the efficacy and safety of adding oral verapamil for 12 months to a standard insulin regimen in adults with recent-onset type 1 diabetes (age range: 18 to 45 years).

1996 to 2013 Saw Large Increase in Diabetes Spending

1996 to 2013 Saw Large Increase in Diabetes Spending

Increased spending per encounter has been the biggest driver of overall rise in spending.

Oral Insulin Choline, Geranate Ionic Liquid Shows Promise

Oral Insulin Choline, Geranate Ionic Liquid Shows Promise

Significant, sustained decrease in blood glucose levels with low insulin doses of 3 to 10 U/kg.

Prevention Program May Reduce Distress, Depression in Adolescents With T1D

Prevention Program May Reduce Distress, Depression in Adolescents With T1D

Investigators examined the effect of the Penn Resilience Program for type 1 diabetes on diabetes-related distress, depressive symptoms, resilience, diabetes self-management, and glycemic control in a cohort of adolescents.

Two Phases of C-Peptide Decline Identified in Type I Diabetes

Two Phases of C-Peptide Decline Identified in Type I Diabetes

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Identifying phases of C-peptide decline may be valuable for understanding β-cell survival.

Diabetes Risk Associated With Cirrhosis, Not Chronic HCV Infection, in HIV+ Patients

Diabetes Risk Associated With Cirrhosis, Not Chronic HCV Infection, in HIV+ Patients

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Cirrhosis is associated with an increased risk for diabetes mellitus among patients living with HIV.

Most Teens, Young Adults With Type 1 Diabetes Report Stigma

Most Teens, Young Adults With Type 1 Diabetes Report Stigma

Stigma is associated with two-fold higher odds of poor glycemic control after adjustment for confounders.

Mini-Dose Glucagon Helps Prevent Exercise-Induced Hypoglycemia in T1D

Mini-Dose Glucagon Helps Prevent Exercise-Induced Hypoglycemia in T1D

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Mini-dose glucagon was as effective as glucose tablets for preventing hypoglycemia and may result in less post intervention hyperglycemia.

ISPAD Issues Consensus Statement on Diabetic Ketoacidosis and Hyperglycemia

ISPAD Issues Consensus Statement on Diabetic Ketoacidosis and Hyperglycemia

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ISPAD recommends adjustments for fluid management regarding rehydration rates in children and adolescents with diabetes ketoacidosis.

ADA: T1D, T2D, GDM Before 26 Weeks Tied to Higher ASD Risk

ADA: T1D, T2D, GDM Before 26 Weeks Tied to Higher ASD Risk

Study shows increased risks of autism spectrum disorder in association with types 1, 2, gestational diabetes.

CAPPRI Scale is Feasible for Assessing Health-Related Quality of Life in Diabetic Distal Sensorimotor Polyneuropathy

CAPPRI Scale is Feasible for Assessing Health-Related Quality of Life in Diabetic Distal Sensorimotor Polyneuropathy

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Investigators evaluated the performance of the CAPPRI in assessing health-related quality-of-life outcomes in patients with diabetic distal sensorimotor polyneuropathy.

Dual-Hormone Artificial Pancreas Reduces Glucose Variability in T1D

Dual-Hormone Artificial Pancreas Reduces Glucose Variability in T1D

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Investigators conducted a randomized crossover comparison of 2 dual-hormone artificial pancreas systems — one with rapid insulin and amylin, and another with regular insulin and amylin — with a rapid insulin-alone artificial pancreas.

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