Type 1 Diabetes Archive

Hippocampal Calcification Associated With Aging, Diabetes, and Smoking

Hippocampal Calcification Associated With Aging, Diabetes, and Smoking

Investigators aim to identify risk factors for hippocampal calcifications and to investigate the relationship between hippocampal calcifications and cognitive function.

Masked High Blood Pressure and Arterial Stiffness in Type 1 Diabetes

Masked High Blood Pressure and Arterial Stiffness in Type 1 Diabetes

Ambulatory blood pressure monitoring in addition to office readings may effectively be able to identify individuals who are at high risk for CVD in T1D.

Anti-Thymocyte Globulin Reduced HbA1C in Newly Diagnosed Type 1 Diabetes

Anti-Thymocyte Globulin Reduced HbA1C in Newly Diagnosed Type 1 Diabetes

Investigators examined the effects of antithymocyte globulin with or without pegylated granulocyte colony-stimulating factor on β-cell function and HbA1C.

Risk for Diabetic Retinopathy With Incretin-Based Therapies

Risk for Diabetic Retinopathy With Incretin-Based Therapies

Investigators examined whether incretin-based therapies increase the risk for diabetic retinopathy compared with other antihyperglycemic agents.

PM2.5 Contributes to Burden of Diabetes Mellitus Globally

PM2.5 Contributes to Burden of Diabetes Mellitus Globally

Particulate matter (PM) with a diameter of less than 2.5 micrograms per cubic meter of air (PM2.5) makes a substantial contribution to the burden of diabetes.

Circadian System, Misalignment Have Distinct Impact on Insulin

Circadian System, Misalignment Have Distinct Impact on Insulin

The endogenous circadian system, behavioral cycle, and circadian misalignment have distinct effects on insulin sensitivity and β-cell function.

Calcium Channel Blocker May Benefit Patients With Type 1 Diabetes

Calcium Channel Blocker May Benefit Patients With Type 1 Diabetes

For this study, researchers conducted a randomized, double-blind, placebo-controlled Phase 2 trial (N=24) to assess the efficacy and safety of adding oral verapamil for 12 months to a standard insulin regimen in adults with recent-onset type 1 diabetes (age range: 18 to 45 years).

1996 to 2013 Saw Large Increase in Diabetes Spending

1996 to 2013 Saw Large Increase in Diabetes Spending

Increased spending per encounter has been the biggest driver of overall rise in spending.

Oral Insulin Choline, Geranate Ionic Liquid Shows Promise

Oral Insulin Choline, Geranate Ionic Liquid Shows Promise

Significant, sustained decrease in blood glucose levels with low insulin doses of 3 to 10 U/kg.

Prevention Program May Reduce Distress, Depression in Adolescents With T1D

Prevention Program May Reduce Distress, Depression in Adolescents With T1D

Investigators examined the effect of the Penn Resilience Program for type 1 diabetes on diabetes-related distress, depressive symptoms, resilience, diabetes self-management, and glycemic control in a cohort of adolescents.

Two Phases of C-Peptide Decline Identified in Type I Diabetes

Two Phases of C-Peptide Decline Identified in Type I Diabetes

Identifying phases of C-peptide decline may be valuable for understanding β-cell survival.

Diabetes Risk Associated With Cirrhosis, Not Chronic HCV Infection, in HIV+ Patients

Diabetes Risk Associated With Cirrhosis, Not Chronic HCV Infection, in HIV+ Patients

Cirrhosis is associated with an increased risk for diabetes mellitus among patients living with HIV.

Most Teens, Young Adults With Type 1 Diabetes Report Stigma

Most Teens, Young Adults With Type 1 Diabetes Report Stigma

Stigma is associated with two-fold higher odds of poor glycemic control after adjustment for confounders.

Mini-Dose Glucagon Helps Prevent Exercise-Induced Hypoglycemia in T1D

Mini-Dose Glucagon Helps Prevent Exercise-Induced Hypoglycemia in T1D

Mini-dose glucagon was as effective as glucose tablets for preventing hypoglycemia and may result in less post intervention hyperglycemia.

ISPAD Issues Consensus Statement on Diabetic Ketoacidosis and Hyperglycemia

ISPAD Issues Consensus Statement on Diabetic Ketoacidosis and Hyperglycemia

ISPAD recommends adjustments for fluid management regarding rehydration rates in children and adolescents with diabetes ketoacidosis.

ADA: T1D, T2D, GDM Before 26 Weeks Tied to Higher ASD Risk

ADA: T1D, T2D, GDM Before 26 Weeks Tied to Higher ASD Risk

Study shows increased risks of autism spectrum disorder in association with types 1, 2, gestational diabetes.

CAPPRI Scale is Feasible for Assessing Health-Related Quality of Life in Diabetic Distal Sensorimotor Polyneuropathy

CAPPRI Scale is Feasible for Assessing Health-Related Quality of Life in Diabetic Distal Sensorimotor Polyneuropathy

Investigators evaluated the performance of the CAPPRI in assessing health-related quality-of-life outcomes in patients with diabetic distal sensorimotor polyneuropathy.

Greater Deficits in Cognitive Function Examined in Diabetes

Greater Deficits in Cognitive Function Examined in Diabetes

Dual-Hormone Artificial Pancreas Reduces Glucose Variability in T1D

Dual-Hormone Artificial Pancreas Reduces Glucose Variability in T1D

Investigators conducted a randomized crossover comparison of 2 dual-hormone artificial pancreas systems — one with rapid insulin and amylin, and another with regular insulin and amylin — with a rapid insulin-alone artificial pancreas.

Improved Glycemic Control With Closed-Loop Insulin Delivery System

Improved Glycemic Control With Closed-Loop Insulin Delivery System

Researchers conducted a randomized, open-label trial to assess the effect of an automated closed-loop insulin delivery system on glycemic control in hospitalized patients.

Technosphere Inhaled Insulin Improves Glycemic Control in Type 1 Diabetes

Technosphere Inhaled Insulin Improves Glycemic Control in Type 1 Diabetes

Patients were randomly assigned to receive insulin aspart or Technosphere inhaled insulin.

MiniMed 670G System Approved for Use in Younger Patients With T1D

MiniMed 670G System Approved for Use in Younger Patients With T1D

The MiniMed 670G system measures glucose levels every 5 minutes and automatically adjusts insulin delivery to avoid highs and lows.

Safety and Performance of Omnipod HCL for Children With Type 1 Diabetes

Safety and Performance of Omnipod HCL for Children With Type 1 Diabetes

In children with type 1 diabetes, the Omnipod hybrid closed-loop personal model system was safe and performed well.

Long-Term Sotagliflozin Safe, Effective as Adjunct Therapy to Insulin in Type 1 Diabetes

Long-Term Sotagliflozin Safe, Effective as Adjunct Therapy to Insulin in Type 1 Diabetes

After insulin optimization, participants with type 1 diabetes were randomly assigned to placebo, sotagliflozin 200 mg, or sotagliflozin 400 mg with insulin.

Chronic Kidney Disease More Common in Type 2 Diabetes Than in Type 1 Diabetes

Chronic Kidney Disease More Common in Type 2 Diabetes Than in Type 1 Diabetes

Investigators examined the prevalence of chronic kidney disease in adults with type 1 diabetes compared with type 2 diabetes.

Preventing Hypoglycemia During Exercise in Type 1 Diabetes on CSII

Preventing Hypoglycemia During Exercise in Type 1 Diabetes on CSII

Reducing basal insulin delivery by 50%-80% 90 minutes before aerobic exercise better prevents hypoglycemia risk vs basal suspension or disconnection at exercise onset.

Implantable Continuous Glucose Monitoring Device Safe, Effective for Adolescents

Implantable Continuous Glucose Monitoring Device Safe, Effective for Adolescents

The safety assessment included incidence of insertion or procedure-related removal and device-related serious adverse events through 180 after insertion.

Treatment for Necrobiosis Lipoidica Gets Orphan Drug Designation

Treatment for Necrobiosis Lipoidica Gets Orphan Drug Designation

The FDA has granted Orphan Drug Designation to PCS499 (Processa Pharmaceuticals) for the treatment of necrobiosis lipoidica.

AMA: Federal Government Must Tackle Rising Insulin Prices

AMA: Federal Government Must Tackle Rising Insulin Prices

U.S. officials need to take action to control spiking insulin prices, the American Medical Association says.

Stressful Life Events in Childhood and Development of Type 1 Diabetes

Stressful Life Events in Childhood and Development of Type 1 Diabetes

Children of parents experiencing stressful and severe life events in early childhood may be at risk for type 1 diabetes developing.

T1D Self-Management Varies With Adult Developmental Stages

T1D Self-Management Varies With Adult Developmental Stages

Researchers examined patterns of diabetes self-management behaviors and predictors of glycemic control in 7,153 adults enrolled in the Type 1 Diabetes Exchange clinic registry.

Asymptomatic Hypoglycemia Risk With Frequent Hypoglycemia in T1D

Asymptomatic Hypoglycemia Risk With Frequent Hypoglycemia in T1D

Investigators recorded hypoglycemic symptoms and monitored blood sugar levels by continuous glucose monitoring for 6 days.

Individuals With Type 1 Diabetes See Improvement With Continuous Glucose Monitoring

Individuals With Type 1 Diabetes See Improvement With Continuous Glucose Monitoring

Investigators seek to determine he effects of continuous glucose monitoring on daytime and nocturnal hypoglycemia in patients with type 1 diabetes.

Oral T1D Treatment Zynquista to Be Reviewed by FDA

Oral T1D Treatment Zynquista to Be Reviewed by FDA

The NDA was supported by data from the Phase 3 inTandem clinical trial program which assessed the safety and efficacy of Zynquista in ~3000 adults with inadequately controlled type 1 diabetes.

Glycemic Control Variations for Children, Adolescents With T1D in High-Income Countries

Glycemic Control Variations for Children, Adolescents With T1D in High-Income Countries

Investigators examined glycemic control variations in 8 high-income countries from multicenter registries in children with type 1 diabetes.

Dual-Hormone System May Lower Time in Hypoglycemia in T1D

Dual-Hormone System May Lower Time in Hypoglycemia in T1D

For physically active adults with type 1 diabetes, the addition of glucagon delivery to a closed-loop system using wearable sensors with automated exercise detection is associated with reduced hypoglycemia.

Exceptional Glycemic Control With Very Low-Carbohydrate Diet

Exceptional Glycemic Control With Very Low-Carbohydrate Diet

For children and adults with type 1 diabetes, consuming a very low-carbohydrate diet is associated with exceptional glycemic control.

FDA: REMS No Longer Needed for Inhaled Insulin Afrezza

FDA: REMS No Longer Needed for Inhaled Insulin Afrezza

Upon review of the proposed supplemental New Drug Application (sNDA), the FDA has determined that the communication plan is no longer needed as an element of the REMS to ensure the benefits of Afrezza outweigh its risks.

Brief Educational Intervention Improves Awareness in Severe Hypoglycemia in T1D

Brief Educational Intervention Improves Awareness in Severe Hypoglycemia in T1D

Brief structured education in addition to informed support in active insulin dose self-adjustment underpinned by targeted self-monitoring of blood glucose lead to sustained falls in severe hypoglycemia rates in individuals at high risk.

Mitochondrial, Muscle Ultrastructural Abnormalities Observed in Skeletal Muscle of Young Adults With T1D

Mitochondrial, Muscle Ultrastructural Abnormalities Observed in Skeletal Muscle of Young Adults With T1D

The study highlights mitochondrial and autophagic differences in the muscles of young adults with type 1 diabetes with moderate glycemic control who exceed recommended activity levels.

CDC Reports on Diabetes Prevalence by Type in the United States

CDC Reports on Diabetes Prevalence by Type in the United States

The CDC conducted a study to estimate the prevalence of diagnosed diabetes among adults in 2016 by primary type.

Risk for Fetal Loss Early in Pregnancy Not Greater With Noninsulin vs Insulin Therapy

Risk for Fetal Loss Early in Pregnancy Not Greater With Noninsulin vs Insulin Therapy

Compared to standard insulin treatment, noninsulin antidiabetic agents did not present an increased risk for fetal losses or major malformations when used in the first trimester of pregnancy.

Artificial Pancreas Treatment Efficacious for Type 1 Diabetes

Artificial Pancreas Treatment Efficacious for Type 1 Diabetes

For patients with type 1 diabetes, artificial pancreas treatment is efficacious, increasing the proportion of time spent in the near normoglycemic range.

Young Adults With Type 1 Diabetes Show Muscle Metabolic Deficiencies

Young Adults With Type 1 Diabetes Show Muscle Metabolic Deficiencies

Physically active young adults with type 1 diabetes have alterations in mitochondrial ultrastructure and bioenergetics within skeletal muscle.

Autism Does Not Affect Metabolic Control in Type 1 Diabetes

Autism Does Not Affect Metabolic Control in Type 1 Diabetes

Awareness of ASD and its manifestations and comorbidities remain imperative in the treatment of T1D, as both conditions require long-term medical follow-up to continue improving diabetes care and metabolic control outcomes.

Distinct Mechanisms Underlie Nerve Damage in Peripheral Neuropathy in T1D vs T2D

Distinct Mechanisms Underlie Nerve Damage in Peripheral Neuropathy in T1D vs T2D

The type of sciatic nerve lesions observed in patients with diabetic peripheral neuropathy was found to differ in type 1 and type 2 diabetes.

Continuous Glucose Monitoring Cost-Effective in Type 1 Diabetes

Continuous Glucose Monitoring Cost-Effective in Type 1 Diabetes

For adults with type 1 diabetes with suboptimal control despite using multiple insulin injections, continuous glucose monitoring seems cost-effective, with improved glucose control.

Pharmacists Can Help With Diabetes Management via Telemedicine

Pharmacists Can Help With Diabetes Management via Telemedicine

Telemedicine could provide real-time feedback loop and allow pharmacists to help patients self-manage.

Altered Neural Responses in Memory Processing With Type 1 Diabetes

Altered Neural Responses in Memory Processing With Type 1 Diabetes

Young adults with type 1 diabetes have altered neural responses during working memory processing.

Consensus Report Defines Treatment Success in β-Cell Replacement Therapy

Consensus Report Defines Treatment Success in β-Cell Replacement Therapy

IPITA and EPITA held a workshop to develop consensus for a joint statement on the definition of function and failure of current and future forms of β-cell replacement therapy.

Glycemic Extremes in T1D Effect Cognitive Skills in Children

Glycemic Extremes in T1D Effect Cognitive Skills in Children

Researchers conducted a systematic literature review to identify studies on cognitive function in children with type 1 diabetes.

Diabetes Does Not Alter Anti-Osteoporotic Treatment Response

Diabetes Does Not Alter Anti-Osteoporotic Treatment Response

Anti-osteoporotic medications (mainly bisphosphonates) seem to equally prevent bone loss, especially in the lumbar spine, in patients with diabetes compared with patients without diabetes.

Risk Factors for Cardiovascular Disease in Youth With Type 1 Diabetes

Risk Factors for Cardiovascular Disease in Youth With Type 1 Diabetes

Early treatment of cardiovascular disease risk factors such as dyslipidemia and hypertension will have long-term benefits with low risk and cost and should be more widely used in pediatric type 1 diabetes care.

Islet Transplantation Improves Quality of Life in Type 1 Diabetes

Islet Transplantation Improves Quality of Life in Type 1 Diabetes

There are significant improvements in health-related quality of life following islet transplantation in patients with type 1 diabetes complicated by severe hypoglycemia.

Accuracy of Novel Implantable Continuous Glucose Monitoring Device Assessed

Accuracy of Novel Implantable Continuous Glucose Monitoring Device Assessed

Researchers assessed the safety and accuracy of an implantable continuous glucose measurement in adults diagnosed with type 1 and type 2 diabetes.

Low-Grade Inflammatory Markers May Help Differentiate Diabetes Diagnoses in Adults

Low-Grade Inflammatory Markers May Help Differentiate Diabetes Diagnoses in Adults

Study provided evidence of significant differences in median serum concentrations of circulating adipose-related inflammatory biomarkers across the main diabetes types.

Dexcom G6 Integrated Continuous Glucose Monitoring System Gets FDA Approval

Dexcom G6 Integrated Continuous Glucose Monitoring System Gets FDA Approval

The FDA reviewed data for the device through the de novo premarket review pathway, a regulatory pathway for novel, low-to-moderate-risk devices that are not substantially equivalent to an already legally marketed device.

Toujeo Max SoloStar Gets FDA Approval for Patients With Diabetes

Toujeo Max SoloStar Gets FDA Approval for Patients With Diabetes

Sanofi announced that the Food and Drug Administration (FDA) has approved Toujeo (insulin glargine 300 Units/mL) Max SoloStar, a long-acting insulin pen that holds 900 Units of Toujeo and provides up to 160 Units/mL per injection.

Physiologic Response to Glucagon in Type 1 Diabetes After Alcohol Consumption

Physiologic Response to Glucagon in Type 1 Diabetes After Alcohol Consumption

Researchers assessed whether alcohol intake affects response to glucagon in individuals with type 1 diabetes.

Sotagliflozin NDA Submitted to FDA for Type 1 Diabetes

Sotagliflozin NDA Submitted to FDA for Type 1 Diabetes

The NDA is based on results from a large placebo-controlled, phase 3 trial that included 1402 patients with type 1 diabetes who were receiving insulin therapy.

Influence of Gender on Cardiovascular Risk and Glycemic Control in T1D

Influence of Gender on Cardiovascular Risk and Glycemic Control in T1D

Researchers assessed differences in glycemic control, major cardiovascular risk factors, diabetes-related complications, sexual dysfunction prevalence, and endothelial function in young men and women with type 1 diabetes.

Closed-Loop Insulin Delivery Offers Best Outcomes for Pregnant Women With T1D

Closed-Loop Insulin Delivery Offers Best Outcomes for Pregnant Women With T1D

For pregnant women with type 1 diabetes, a closed-loop system is associated with comparable glucose control and significantly less hypoglycemia than sensor-augmented pump therapy.

MiniMed 670G System Improves Glycemic Outcomes in Children With T1D

MiniMed 670G System Improves Glycemic Outcomes in Children With T1D

Research findings indicate improved glycemic outcomes in children with T1D using the MiniMed 670G system, similar to those observed for adolescents and adults.

Minority Youths With T1D Have Poor Prognostic Factors, More Complications

Minority Youths With T1D Have Poor Prognostic Factors, More Complications

Researchers assessed racial and ethnic differences in outcomes among patients in the first 3 years following diagnosis of type 1 diabetes.

Proliferative Diabetic Retinopathy Independently Associated With CVD in T1D

Proliferative Diabetic Retinopathy Independently Associated With CVD in T1D

Study found that the absence of proliferative diabetic retinopathy in those with stage 3b chronic kidney disease is associated with a lower prevalence of cardiovascular disease in patients with long duration of type 1 diabetes.

Preventing Nocturnal Hypoglycemia: Single- vs Dual-Hormone Artificial Pancreas System

Preventing Nocturnal Hypoglycemia: Single- vs Dual-Hormone Artificial Pancreas System

Study suggests that single-hormone artificial pancreas systems may be sufficient for overnight control even in a high-risk group of hypoglycemia-unaware participants with documented nocturnal hypoglycemia.

Effect of Glycemic Control During Labor on Neonatal Hypoglycemia Examined

Effect of Glycemic Control During Labor on Neonatal Hypoglycemia Examined

High-quality studies are needed to determine whether tight intrapartum glycemic control is superior to more relaxed glycemic targets intrapartum for women with diabetes in pregnancy.

Parental History of T1D May Increase Risk for ADHD in Offspring

Parental History of T1D May Increase Risk for ADHD in Offspring

Researchers calculated the hazard ratio of ADHD in offspring of patients with type 1 diabetes compared with the general population.

Disordered Eating Affects HbA1c in Adolescents With Type 1 Diabetes

Disordered Eating Affects HbA1c in Adolescents With Type 1 Diabetes

For youth with type 1 diabetes, disordered eating behaviors are associated with higher hemoglobin A1c but not with measures of glycemic variability.

Women With T1D, T2D Receiving Increased Intervention in Pregnancy

Women With T1D, T2D Receiving Increased Intervention in Pregnancy

Higher rates of operative delivery and falling gestational age at delivery suggest that this is either reflected by, or despite, increasing obstetric intervention.

Genetic Variants Linked to Phenotypic Heterogeneity of Type 1 Diabetes

Genetic Variants Linked to Phenotypic Heterogeneity of Type 1 Diabetes

Transcription factor 7 like 2 genetic variants contribute to phenotypic heterogeneity of type 1 diabetes.

T1D, T2D May Have Protective Effects on Risk for Migraine

T1D, T2D May Have Protective Effects on Risk for Migraine

Results from a study investigating diabetes and migraine in the Norwegian population show that type 1 and type 2 diabetes were significantly associated with a decreased risk for migraine.

Type 1 Diabetes Associated With Higher Rates of Serious Infection

Type 1 Diabetes Associated With Higher Rates of Serious Infection

Patients with diabetes had higher rates for all 19 infection categories with the highest incidence rate ratios seen for bone and joint infections, sepsis, and cellulitis.

No Difference in Hydrolyzed vs Conventional Formula Among Infants at Risk for T1D

No Difference in Hydrolyzed vs Conventional Formula Among Infants at Risk for T1D

Weaning to a hydrolyzed formula did not reduce the risk of type 1 diabetes in children with an increased disease risk.

Trends in CVD, Risk Factors, and Medications in Children With T1D

Trends in CVD, Risk Factors, and Medications in Children With T1D

Children with T1D had statistically significantly higher prevalence rates of hypertension, hypercholesterolemia, and used more CV medication compared with a matched diabetes-free reference cohort in the period after the onset of diabetes.

Safety of Novel Soluble Glucagon Analog for Severe Hypoglycemia in T1D Evaluated

Safety of Novel Soluble Glucagon Analog for Severe Hypoglycemia in T1D Evaluated

Dasiglucagon is well-tolerated and is associated with an early pharmacodynamic response similar to that of GlucaGen for severe hypoglycemia.

Alum-Formulated Glutamate Decarboxylase Injections Safe for Prediabetic Children

Alum-Formulated Glutamate Decarboxylase Injections Safe for Prediabetic Children

Study evaluated the safety and efficacy of autoantigen-specific therapy with alum-formulated glutamate decarboxylase in nondiabetic children with multiple islet autoantibodies.

Cumulative Risk of ESRD Decreased Over Time for T1D

Cumulative Risk of ESRD Decreased Over Time for T1D

The cumulative risk of end-stage renal disease among patients with type 1 diabetes has declined over time in Finland.

Depression and Severe Dysglycemia Associated Bidirectionally in T1D

Depression and Severe Dysglycemia Associated Bidirectionally in T1D

For patients with type 1 diabetes, there is a bidirectional association between depression and severe hypoglycemia and hyperglycemia.

Increased Risk of Type 1 Diabetes in Children With Asthma

Increased Risk of Type 1 Diabetes in Children With Asthma

A previous diagnosis of asthma increases the risk for subsequent type 1 diabetes by 41%, but a previous diagnosis of type 1 diabetes decreases the risk of subsequent asthma by 18%.

Does Genetic Susceptibility Lead to Late-Onset Type 1 Diabetes?

Does Genetic Susceptibility Lead to Late-Onset Type 1 Diabetes?

In older adults, in whom T1D is rare, patients with diabetes who are positive for autoantibodies are as likely to be false positive with T2D as true positive with T1D.

Corticosteroids Linked With Risk for Fracture, VTE, Sepsis in Diabetes

Corticosteroids Linked With Risk for Fracture, VTE, Sepsis in Diabetes

Corticosteroids should be used with caution in patients with diabetes and mitigating factors should be considered.

Vascular Endothelial Dysfunction Involved in Hypertension Development in T1D

Vascular Endothelial Dysfunction Involved in Hypertension Development in T1D

A life-course study evaluated the contribution of vascular endothelial dysfunction and inflammation to the development of hypertension in type 1 diabetes.

Real-Time Continuous Glucose Monitoring Beneficial But Challenges Remain

Real-Time Continuous Glucose Monitoring Beneficial But Challenges Remain

Although sharing of real-time continuous glucose monitoring data can create tension between patients with type 1 diabetes and family members, it can also facilitate greater empowerment and perceptions of safety among both patients and their caregivers.

Effect of SGLT2 Inhibitors on Early Metabolic Decompensation in T1D

Effect of SGLT2 Inhibitors on Early Metabolic Decompensation in T1D

Patients with T1D are not susceptible to accelerated lipolysis and ketogenesis, despite the reduction in overnight basal insulin doses during SGLT2i treatment.

Identifying Risk for Microalbuminuria in Children With Type 1 Diabetes

Identifying Risk for Microalbuminuria in Children With Type 1 Diabetes

Study sought to evaluate whether baseline autonomic dysfunction was predictive of future increases in urine albumin-creatinine ratio in pediatric patients with type 1 diabetes.

Psychosocial Benefits of a Bihormonal Bionic Pancreas System in T1D

Psychosocial Benefits of a Bihormonal Bionic Pancreas System in T1D

Participants reported improvements in many psychosocial variables associated with using an automated bihormonal bionic pancreas system relative to self-management of diabetes using their own insulin pump.

Oral Insulin Not a Reliable Preventive Strategy for Type 1 Diabetes

Oral Insulin Not a Reliable Preventive Strategy for Type 1 Diabetes

Investigators sought to delay or prevent the onset of type 1 diabetes by administering a once-daily oral insulin tablet.

New Report Standardizes Clinically Meaningful T1D Outcomes Beyond HbA1c Testing

New Report Standardizes Clinically Meaningful T1D Outcomes Beyond HbA1c Testing

Representatives from multiple associations and societies have issued a new report standardizing clinically meaningful outcome measures for type 1 diabetes, beyond using HbA1c testing.

Effects of Peer Influence in Adolescents With Type 1 Diabetes

Effects of Peer Influence in Adolescents With Type 1 Diabetes

Study underscores the need to focus on the peer context to understand the functioning of youths with type 1 diabetes.

Improving Daily Glucose Monitoring in Adolescents With Incentive-Based Approach

Improving Daily Glucose Monitoring in Adolescents With Incentive-Based Approach

Incentive-based approaches developed to improve daily adherence to a single behavioral process, such as blood glucose monitoring in adolescents, may not be as effective as multicomponent interventions that address emotional, social, and family processes of diabetes self-management.

Utilizing Trend Arrow Data in CGM Systems to Manage Diabetes in Children

Utilizing Trend Arrow Data in CGM Systems to Manage Diabetes in Children

Recommendations for utilizing trend arrow data in a mobile continuous glucose monitoring system were recently issued for pediatric patients with type 1 diabetes.

Effect of Prior Glucose Monitoring on Glycemic Outcomes With a Hybrid Closed-Loop System

Effect of Prior Glucose Monitoring on Glycemic Outcomes With a Hybrid Closed-Loop System

Patients with prior experience using a continuous glucose monitoring system may benefit from the MiniMed 670G HCL system therapy.

Remotely Connected Diabetes System Improves Glycemic Control in Insulin-Treated Diabetes

Remotely Connected Diabetes System Improves Glycemic Control in Insulin-Treated Diabetes

A remotely connected diabetes management system increased patent satisfaction and improved glycemic control in patients with insulin-treated diabetes.

Leptin Levels Associated With Risk for Preeclampsia in Women With T1D

Leptin Levels Associated With Risk for Preeclampsia in Women With T1D

Investigators believe that circulating adipokines may be associated with the development of preeclampsia in women with type 1 diabetes in the first trimester.

Improved Neonatal Outcomes With Continuous Glucose Monitoring in T1D

Improved Neonatal Outcomes With Continuous Glucose Monitoring in T1D

Investigators assess maternal hyperglycemia exposure to fetus with neonatal health outcomes.

Childhood Antibiotic Use Not Linked to Islet or Celiac Disease Autoimmunity

Childhood Antibiotic Use Not Linked to Islet or Celiac Disease Autoimmunity

Islet and celiac disease autoimmunity were defined as a positive test result for islet or tissue transglutaminase autoantibodies at 2 clinic visits at least 3 months apart.

Low Incidence of ESRD Reported in Childhood-Onset Type 1 Diabetes

Low Incidence of ESRD Reported in Childhood-Onset Type 1 Diabetes

Among patients with childhood-onset type 1 diabetes, there is a very low incidence of end-stage renal disease.

Glycemic Control Improved With Addition of Sotagliflozin to Insulin

Glycemic Control Improved With Addition of Sotagliflozin to Insulin

Study assessed the effects of sotagliflozin vs placebo with respect to glycemic control and the occurrence of severe hypoglycemia and diabetic ketoacidosis among adults with type 1 diabetes.

Adjunctive Dapagliflozin Improves Glycemic Control in T1D

Adjunctive Dapagliflozin Improves Glycemic Control in T1D

Dapagliflozin improves glycemic control in patients with inadequately controlled type 1 diabetes currently taking insulin.

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