Thyroid

Subclinical Thyroid Dysfunction Not Associated With Hip Fracture Risk in Older Men

Subclinical Thyroid Dysfunction Not Associated With Hip Fracture Risk in Older Men

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Findings do not support a role for subclinical thyroid dysfunction as a biomarker for bone-related outcomes in older men.

Tafinlar + Mekinist Approved for BRAF-Positive Anaplastic Thyroid Cancer

Tafinlar + Mekinist Approved for BRAF-Positive Anaplastic Thyroid Cancer

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Study data showed 57% of evaluable patients (N=23) had a partial response and 4% achieved a complete response. Among the 14 responders, 64% did not have significant tumor growths for ≥6 months.

Risk for Iodine Deficiency and Hypothyroidism High in Children on Parenteral Nutrition

Risk for Iodine Deficiency and Hypothyroidism High in Children on Parenteral Nutrition

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Study is the first to reveal a higher prevalence of iodine deficiency and hypothyroidism in children receiving chronic parenteral nutrition.

Nivolumab Associated With Thyroiditis in Patients With Cancer

Nivolumab Associated With Thyroiditis in Patients With Cancer

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Destructive thyroiditis was a frequently observed endocrine immune-related adverse event induced by nivolumab treatment and was significantly associated with the existence of anti-thyroglobulin antibodies and/or anti-thyroid peroxidase antibodies prior to treatment.

FT3 Level Associated With the Development of Metabolic Syndrome

FT3 Level Associated With the Development of Metabolic Syndrome

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Researchers designed a cohort study to examine whether serum thyroid hormone levels within the reference range are predictive factors for developing metabolic syndrome in adults.

Diagnostic Value of Shear Wave Elastography for Parathyroid Adenomas

Diagnostic Value of Shear Wave Elastography for Parathyroid Adenomas

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Shear wave elastography can be a useful tool in the preliminary diagnostics of parathyroid adenomas.

Treating Moderate to Severe Graves' Orbitopathy: Methylprednisolone Alone vs Combined With Mycophenolate

Treating Moderate to Severe Graves' Orbitopathy: Methylprednisolone Alone vs Combined With Mycophenolate

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This study is the first to investigate the efficacy and safety of add-on mycophenolate to methylprednisolone for moderate to severe Graves' orbitopathy.

Pregnancy Outcomes With Levothyroxine in Women Positive for Antithyroperoxidase Antibodies

Pregnancy Outcomes With Levothyroxine in Women Positive for Antithyroperoxidase Antibodies

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Levothyroxine treatment did not appear to improve pregnancy outcomes in women with thyroid autoantibodies undergoing in vitro fertilization and embryo transfer.

Risk for Congenital Malformations With Antithyroid Drugs

Risk for Congenital Malformations With Antithyroid Drugs

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Antithyroid drug exposure during the first trimester was associated with an increased risk for congenital malformations.

Denosumab May Increase BMD in Women With Primary Hyperparathyroidism

Denosumab May Increase BMD in Women With Primary Hyperparathyroidism

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Study assessed the effect of denosumab on bone mineral density and incident fractures in older adults with primary hyperparathyroidism who could not undergo or refused surgery.

Unexplained Infertility Linked to Higher Thyroid-Stimulating Hormone in Women

Unexplained Infertility Linked to Higher Thyroid-Stimulating Hormone in Women

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Study raises the question of whether treatment with thyroid hormone replacement for individuals with TSH levels >2.5 mIU/L may be an economical first step in treating unexplained infertility.

BMD and Parathyroid Hormone Levels in Pseudohypoparathyroidism 1B

BMD and Parathyroid Hormone Levels in Pseudohypoparathyroidism 1B

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Study showed that parathyroid hormone was a significant predictor of lumbar spine bone mineral density Z-score for pseudohypoparathyroidism 1B patients.

First trimester exposure to antithyroid drugs associated with increased risk of birth defects

First trimester exposure to anytithyroid drugs was associated with a greater risk of congenital malformations, especially for pregnant women who were given prescriptions for methimazole or both methimazole and propylthiouracil.

Thyroid hormone supplementation may be a promising treatment for idiopathic pulmonary fibrosis [PreClinical]

An enzyme involved in thyroid hormone activation was found to be elevated in patients with pulmonary fibrosis.

Evaluating Surgery Performance and Care Quality in Thyroidectomy

Evaluating Surgery Performance and Care Quality in Thyroidectomy

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Investigators aimed to determine strategies for improvement to reduce complications after thyroidectomy.

Thyroid Cancer Less Likely to Progress in Pediatrics, Young Adults

Thyroid Cancer Less Likely to Progress in Pediatrics, Young Adults

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An observational study was conducted by investigators to evaluate the progression of thyroid cancer in young individuals by ultrasonography.

Validation of Ultrasound Risk Stratification Systems for Pediatric Thyroid Nodules

Validation of Ultrasound Risk Stratification Systems for Pediatric Thyroid Nodules

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Investigators assessed the utilization of ATA risk stratification and TI-RADS ultrasound based systems for the assessment of pediatric thyroid nodules.

Imaging Studies in Hypothyroidism Evaluation Linked to Unnecessary Risks

Imaging Studies in Hypothyroidism Evaluation Linked to Unnecessary Risks

Thyroid ultrasonography, which may lead to the discovery of incidental nodules, anxiety, and high cost, is not required in evaluation for hypothyroidism.

Transoral Endoscopic Thyroidectomy Vestibular Approach: Safety and Outcomes

Transoral Endoscopic Thyroidectomy Vestibular Approach: Safety and Outcomes

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The transoral endoscopic thyroidectomy vestibular approach can be a safe procedure in select patients, with outcomes similar to those of open thyroidectomy.

Wide Variation Noted in Total, Partial Thyroidectomy Rates by US Region

Wide Variation Noted in Total, Partial Thyroidectomy Rates by US Region

A 6.2-fold variation in thyroidectomy rates was noted throughout the US.

Predicting Hypocalcemia in Children Following Thyroidectomy: Is PTH Level Useful?

Predicting Hypocalcemia in Children Following Thyroidectomy: Is PTH Level Useful?

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While parathyroid hormone levels may be used to anticipate calcium decline, a "normal" PTH level does not always correctly predict postoperative calcium level.

Safety, Efficacy of Early Thyroidectomy in Pediatric MEN2

Safety, Efficacy of Early Thyroidectomy in Pediatric MEN2

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Early thyroidectomy was preventative in a majority of pediatric patients with MEN2.

Proper Treatment in Children With Congenital Hypothyroidism Can Aid Behavior

Proper Treatment in Children With Congenital Hypothyroidism Can Aid Behavior

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Both over- and undertreatment of congenital hypothyroidism can result in negative behavioral outcomes.

Central Congenital Hypothyroidism Detection in Neonates

Central Congenital Hypothyroidism Detection in Neonates

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Screening programs that measure T4 with reflex TSH in newborns with T4 below a specified cutoff have the potential to detect central congenital hypothyroidism (CCH) and have shown a higher prevalence of CCH than previously thought.

AAP Shares List of 5 Unnecessary Pediatric Tests and Procedures

AAP Shares List of 5 Unnecessary Pediatric Tests and Procedures

The American Academy of Pediatrics urges careful consideration between parents and clinicians prior to ordering these tests.

Watch and Wait: Examining Rates of Tumor Growth in Active Thyroid Surveillance

Watch and Wait: Examining Rates of Tumor Growth in Active Thyroid Surveillance

No regional or distant metastases developed during active surveillance in low-risk patients.

Does Thyroxine Tx in Hypothyroidism Cause Thyroid Cancer?

Does Thyroxine Tx in Hypothyroidism Cause Thyroid Cancer?

Irregular users of thyroxine were less likely to develop thyroid cancer compared to regular users.

Impaired Vascular Dysfunction in Primary Hyperparathyroidism May Impact Cognition

Impaired Vascular Dysfunction in Primary Hyperparathyroidism May Impact Cognition

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It has been previously reported that parathyroidectomy can reverse cognitive dysfunction associated with primary hyperparathyroidism.

Thyroid Dysfunction Not a Risk Factor for Carotid Plaque Development

Thyroid Dysfunction Not a Risk Factor for Carotid Plaque Development

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Subclinical thyroid dysfunction did not influence the cumulative incidence of new carotid plaques in healthy individuals aged 20 or older.

Radioiodine Therapy and Hemorrhagic Stoke: Are Risk Levels Increased?

Radioiodine Therapy and Hemorrhagic Stoke: Are Risk Levels Increased?

Stroke risk with I-131 therapy for thyroid cancer was examined via 2 cohorts using 1:1 propensity score matching.

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