Thyroid Cancer Archive

Unresected Anaplastic Thyroid Cancer Linked to Poor Overall Survival

Unresected Anaplastic Thyroid Cancer Linked to Poor Overall Survival

For patients with unresected anaplastic thyroid carcinoma, overall survival is poor, but radiation therapy dose is associated with improved survival.

USPSTF Still Recommending Against Routine Thyroid Cancer Screening

USPSTF Still Recommending Against Routine Thyroid Cancer Screening

Widespread routine thyroid cancer screening can lead to overdiagnosis and overtreatment, according to the statement.

Core-Needle Biopsy vs Fine-Needle Aspiration for Thyroid Nodules

Core-Needle Biopsy vs Fine-Needle Aspiration for Thyroid Nodules

Does core-needle biopsy perform better than repeat fine-needle aspiration for evaluating thyroid nodules?

Two Genetic Mutations Linked to Tumor Behavior in Thyroid Cancer Patients

Two Genetic Mutations Linked to Tumor Behavior in Thyroid Cancer Patients

CDC27 mutations may be associated with less aggressive behavior while SLC25A5 mutations may be associated with more aggressive behavior in papillary thyroid carcinomas.

New Agent May Offer Hope in Treating Thyroid Cancer

New Agent May Offer Hope in Treating Thyroid Cancer

The first-in-class compound CUDC-907, which is being tested for multiple myeloma and refractory lymphoma, may be promising for anaplastic thyroid cancer and poorly differentiated thyroid cancer.

Recurrence Rates Low After rhTSH for Postoperative Ablation in Low-Risk Thyroid Cancer

Recurrence Rates Low After rhTSH for Postoperative Ablation in Low-Risk Thyroid Cancer

Long-term recurrence rates appear to be low following the use of recombinant human thyrotropin for postoperative ablation in low-risk thyroid cancer.

Sequential Combination Strategy May Be Optimal in Advanced Thyroid Cancer

Sequential Combination Strategy May Be Optimal in Advanced Thyroid Cancer

Initiating treatment with the mTor inhibitor everolimus followed by the somatostatin analogue pasireotide may be beneficial in advanced thyroid cancer.

Prospective Study Confirms ATA Sonographic Pattern Risk Assessment Guidelines

Prospective Study Confirms ATA Sonographic Pattern Risk Assessment Guidelines

A new study has validated the American Thyroid Association sonographic pattern for selection of thyroid nodules undergoing ultrasound-guided fine needle aspiration.

Active Surveillance May Be Appropriate in Select Thyroid Cancer Patients

Active Surveillance May Be Appropriate in Select Thyroid Cancer Patients

Active surveillance in low-risk thyroid cancer may be better than immediate surgery in some patients.

Close Monitoring May Improve Outcomes With Lenvatinib in Differentiated Thyroid Cancer

Close Monitoring May Improve Outcomes With Lenvatinib in Differentiated Thyroid Cancer

Despite side effects, patients with differentiated thyroid cancer taking lenvatinib may experience better outcomes with close monitoring.

Liquid Biopsy May Help Predict Survival in Medullary Thyroid Carcinoma

Liquid Biopsy May Help Predict Survival in Medullary Thyroid Carcinoma

Liquid biopsy may prevent the need for unnecessary biopsies in patients with medullary thyroid carcinoma.

Study Identifies Risk Estimates for Occult Nodal Disease After Thyroidectomy

Study Identifies Risk Estimates for Occult Nodal Disease After Thyroidectomy

Researchers have identified estimates for risk of occult nodal disease of patients with papillary thyroid cancer who have undergone surgery.

Imaging After Thyroid Cancer Treatment May Not Improve Survival

Imaging After Thyroid Cancer Treatment May Not Improve Survival

More imaging tests after treatment does not always lead to an improvement in thyroid cancer patients' chances of survival.

Impact of Drug, Genomic Innovations on Thyroid Cancer Treatment

Impact of Drug, Genomic Innovations on Thyroid Cancer Treatment

There were no effective therapeutic options for advanced thyroid cancer until 5 years ago.

Thyroid Cancer Rates Leveling Off

Thyroid Cancer Rates Leveling Off

The recent increase may be caused by an 'epidemic of diagnosis,' not harmful tumors, researchers said.

Thyroid Cancer Progression Slowed With Dose Escalation of IMRT

Thyroid Cancer Progression Slowed With Dose Escalation of IMRT

Local-regional failure in well-differentiated thyroid cancer mostly occurs outside of 70 Gy volume and in peri-esophageal region.

Complications After Thyroidectomy Less Likely With High-Volume Surgeons

Complications After Thyroidectomy Less Likely With High-Volume Surgeons

The risk for complications was 87% higher when a surgeon's case load is1 thyroidectomy case a year.

Study: Survival Is 'Excellent' in Pediatric Differentiated Thyroid Cancer

Study: Survival Is 'Excellent' in Pediatric Differentiated Thyroid Cancer

However, nearly one-third of patients develop lifelong complications following thyroid surgery.

Thyroid Cancer Risk Up After Breast Cancer

Thyroid Cancer Risk Up After Breast Cancer

The likelihood of developing breast or thyroid cancer as a secondary malignancy is increased following diagnosis of the other cancer.

Gene Expression Classifier May Reduce Thyroid Surgery Rate

Gene Expression Classifier May Reduce Thyroid Surgery Rate

Physicians using gene expression classifier testing said that in 86% of cases, identifying a benign result through testing and potentially avoiding surgery improved patient safety.

Second Primary Malignancies Identified Among Patients With Post-Chernobyl Papillary Thyroid Cancer

Second Primary Malignancies Identified Among Patients With Post-Chernobyl Papillary Thyroid Cancer

Second primary malignancies among patients with post-Chernobyl papillary thyroid cancer include hematological malignancies, breast carcinoma, cervical carcinoma, and colon carcinomas.

Thyroid Cancer Survivors Report Poor Quality of Life

Thyroid Cancer Survivors Report Poor Quality of Life

Patients with thyroid cancer report worse quality of life than others diagnosed with more lethal cancers.

Gene Variant, Fusion Panels Alone Do Not Rule In, Rule Out Thyroid Cancer

Gene Variant, Fusion Panels Alone Do Not Rule In, Rule Out Thyroid Cancer

Genetic alterations were found in both cancerous and benign samples.

Aggressive Multimodal Therapy May Up Survival in Anaplastic Thyroid Cancer

Aggressive Multimodal Therapy May Up Survival in Anaplastic Thyroid Cancer

Results in this expanded series reaffirm the data in the pilot study and show a 5-year overall survival rate of 43%.

Cabozantinib Improved Survival in Medullary Thyroid Cancer With RET Mutations

Cabozantinib Improved Survival in Medullary Thyroid Cancer With RET Mutations

Patients with medullary thyroid cancer taking cabonzantinib lived more than 2 years longer if their tumors had a RET mutation.

Diet Not Linked With Thyroid Cancer

Diet Not Linked With Thyroid Cancer

New results show no significant associations between dietary habits and thyroid cancer risk.

Complication Rates After Thyroidectomy Lower With High-Volume Surgeons

Complication Rates After Thyroidectomy Lower With High-Volume Surgeons

Rates lower for surgeons performing 25 or more total thyroidectomies a year.

New Nomogram Predicts Death, Recurrence Risk in Papillary Thyroid Cancer

New Nomogram Predicts Death, Recurrence Risk in Papillary Thyroid Cancer

Excellent accuracy for 10-year disease-specific death, recurrence.

Obesity May Raise Thyroid Cancer Risk

Obesity May Raise Thyroid Cancer Risk

Positive link to papillary, follicular, anaplastic thyroid cancer; inverse link for medullary thyroid cancer.

Advanced Imaging May Account for Increase in Thyroid Cancer Detection

Advanced Imaging May Account for Increase in Thyroid Cancer Detection

Many cases involve low-risk tumors where treatments could carry greater risks than benefits.

Recombinant TSH Better After Thyroid Cancer Radioiodine Ablation

Recombinant TSH Better After Thyroid Cancer Radioiodine Ablation

Recombinant human TSH avoids transient health-related quality-of-life deterioration seen with thyroid hormone withdrawal.

Cervical Lymph Node Metastases Linked to Lower Survival in Thyroid Cancer

Cervical Lymph Node Metastases Linked to Lower Survival in Thyroid Cancer

Cervical lymph node metastases are associated with compromised survival in young patients with papillary thyroid cancer.

In Thyroid Cancer, Acupuncture May Effectively Treat Radioactive Iodine-Induced Anorexia

In Thyroid Cancer, Acupuncture May Effectively Treat Radioactive Iodine-Induced Anorexia

Acupuncture may be an effective treatment for patients with thyroid cancer who experience radioactive-iodine-induced (RAI)-induced anorexia.

HABP2 Mutation Confers Susceptibility to Thyroid Cancer

HABP2 Mutation Confers Susceptibility to Thyroid Cancer

HABP2 G534E variant is a susceptibility gene for familial nonmedullary thyroid cancer and functions as a dominant-negative tumor-suppressor gene.

Molecular Testing Advances Prompt Updated Thyroid Cancer Guidelines

Molecular Testing Advances Prompt Updated Thyroid Cancer Guidelines

New developments in molecular profiling have been included in an updated position statement on thyroid cancer.

Effect of Timing of Postop Radioactive Iodine Ablation in PTC

Effect of Timing of Postop Radioactive Iodine Ablation in PTC

Timing of radioactive iodine ablation doesn't affect overall survival in papillary thyroid cancer.

Sonographic Pattern Stratifies Thyroid Nodule Malignancy Risk

Sonographic Pattern Stratifies Thyroid Nodule Malignancy Risk

Sonographic pattern should be used to determine the threshold for thyroid nodule biopsy and can stratify the risk for malignancy.

Levothyroxine Dose May Differ for Obese Women After Thyroidectomy

Levothyroxine Dose May Differ for Obese Women After Thyroidectomy

Obese women who undergo thyroidectomy may require a higher dose of levothyroxine than nonobese women.

Proposed ATA Guidelines' Sonographic Patterns Performance for MTC

Proposed ATA Guidelines' Sonographic Patterns Performance for MTC

New sonographic patterns proposed in the provisional 2014 ATA guidelines perform well for medullary thyroid cancer.

ATA Releases First Guidelines for Thyroid Nodules, Thyroid Cancer in Children

ATA Releases First Guidelines for Thyroid Nodules, Thyroid Cancer in Children

The American Thyroid Association has released the first guidelines for evaluating and managing thyroid nodules and thyroid cancer in pediatric patients.

Thyroid Cancer Risk Increased After Breast Cancer

Thyroid Cancer Risk Increased After Breast Cancer

The risk for thyroid cancer appears to be increased in breast cancer survivors, especially among younger patients with invasive ductal carcinoma.

Could Dogs Sniff Out Thyroid Cancer?

Could Dogs Sniff Out Thyroid Cancer?

A trained scent dog was able to accurately identify thyroid cancer in urine samples from patients with thyroid nodules.

Sunitinib May Benefit Patients With Advanced Differentiated Thyroid Cancer

Sunitinib May Benefit Patients With Advanced Differentiated Thyroid Cancer

Sunitinib appears to exhibit significant antitumor activity in patients with advanced differentiated thyroid cancer.

Benign Thyroid Nodules May Require Less Aggressive Follow-Up

Benign Thyroid Nodules May Require Less Aggressive Follow-Up

After 5 years, less than 1% of asymptomatic nodules studied were diagnosed as thyroid cancer.

Lenvima Wins FDA Approval for Advanced Thyroid Cancer

Lenvima Wins FDA Approval for Advanced Thyroid Cancer

Drug approved to treat progressive, differentiated thyroid cancer that is refractory to radioactive iodine therapy.

Lenvatinib Improved Survival in I-131-Refractory Thyroid Cancer

Lenvatinib Improved Survival in I-131-Refractory Thyroid Cancer

Lenvatinib improved progression-free survival and response rate in I-131-refractory thyroid cancer.

Radioactive Iodine Improved Outcomes in Intermediate-Risk Thyroid Cancer

Radioactive Iodine Improved Outcomes in Intermediate-Risk Thyroid Cancer

Radioactive iodine therapy was associated with improved survival and reduced mortality risk.

Radiation Effects on Thyroid Nodules in Atomic Bomb Survivors

Radiation Effects on Thyroid Nodules in Atomic Bomb Survivors

Radiation effects on thyroid nodules were noted in people who survived the atomic bombings at Hiroshima and Nagasaki.

Prognostic Factors of Sorafenib Treatment Outcomes Identified

Prognostic Factors of Sorafenib Treatment Outcomes Identified

Maximum tumor size may predict outcomes after treatment with sorafenib in radioactive iodine-refractory differentiated thyroid cancer.

Next-Generation Sequencing Test Promising for Diagnosis of Indeterminate Thyroid Nodules

Next-Generation Sequencing Test Promising for Diagnosis of Indeterminate Thyroid Nodules

A next-generation sequencing panel of genetic markers may improve cancer diagnosis of indeterminate thyroid nodules.

Sex Hormones May Play Role in Follicular Thyroid Cancer

Sex Hormones May Play Role in Follicular Thyroid Cancer

Sex hormones may account for the differences between men and women in the development of follicular thyroid cancer.

New Assay May Help Guide Therapy in Papillary Thyroid Cancer

New Assay May Help Guide Therapy in Papillary Thyroid Cancer

A blood assay that measures BRAF mutation levels may be helpful in diagnosing and monitoring papillary thyroid cancer.

Moderate Thyroid Hormone Suppression Superior in Thyroid Cancer

Moderate Thyroid Hormone Suppression Superior in Thyroid Cancer

Only moderate suppression of thyroid-stimulating hormone improves outcomes in all stages of differentiated thyroid cancer.

Radioiodine Has Small Benefit in Papillary Thyroid Cancer

Radioiodine Has Small Benefit in Papillary Thyroid Cancer

Radioactive iodine therapy may slightly improve survival in papillary thyroid carcinoma.

Combining Lithium With Radioactive Iodine Therapy for Metastatic Radioiodine-Refractory Thyroid Cancer

Combining Lithium With Radioactive Iodine Therapy for Metastatic Radioiodine-Refractory Thyroid Cancer

Combining lithium with radioactive iodine therapy may improve survival in patients with metastatic radioiodine-refractory thyroid cancer.

Low-Activity I-131 Not Optimal in Differentiated Thyroid Cancer

Low-Activity I-131 Not Optimal in Differentiated Thyroid Cancer

Radioactive iodine therapy with low-activity I-131 may result in worse survival and more radiation exposure in patients with differentiated thyroid cancer.

Thyroid, Renal Cancers Increasing in Children

Thyroid, Renal Cancers Increasing in Children

The incidence of renal cancer and thyroid cancer is increasing among children and adolescents in the United States.

Thyroid Cancer, Nodular Disease Risk Increased in Acromegaly

Thyroid Cancer, Nodular Disease Risk Increased in Acromegaly

Thyroid nodular disease and thyroid cancer prevalence appears to be higher in patients with acromegaly.

Pediatric Thyroid Cancer Patients Require Long-Term Follow-Up

Pediatric Thyroid Cancer Patients Require Long-Term Follow-Up

Long-term follow-up is important in children with thyroid cancer to prevent late recurrence.

Lenvatinib Promising for Radioiodine-Resistant Thyroid Cancer

Lenvatinib Promising for Radioiodine-Resistant Thyroid Cancer

Lenvatinib, a new TKI inhibitor, delays disease progression and shows promising clinical efficacy against differentiated radioiodine-resistant thyroid cancer.

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